PCS-200-013 Search Results


primary epidermal melanocytes  (ATCC)
99
ATCC primary epidermal melanocytes
K‐Means Elbow Plot and Hierarchical Clustering Dendrogram comparing <t>melanocytes</t> and SK‐MEL‐2 cells using morphological, positional, geometric, phaseshift, roughness, and texture parameters. The K‐Means Elbow Plot (A) characterizes the optimal number of data clusters within the melanocyte and SK‐MEL‐2 data sets, as demonstrated by the “elbow” in the plot. The Hierarchical Clustering Dendrogram (B) visualizes the clustering of data points based on their similarity. The great height difference before breaking into two branches demonstrates a great difference between the two cell lines. These findings from the K‐Means Elbow Plot and Hierarchical Clustering Dendrograms suggest that the selected features highlight the differences between melanocytes and SK‐MEL‐2 cells. The plots were visualized using R (version 4.0.5). Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.
Primary Epidermal Melanocytes, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/primary epidermal melanocytes/product/ATCC
Average 99 stars, based on 1 article reviews
primary epidermal melanocytes - by Bioz Stars, 2026-02
99/100 stars
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pcs-200-013  (LGC Standards)
95
LGC Standards pcs-200-013
K‐Means Elbow Plot and Hierarchical Clustering Dendrogram comparing <t>melanocytes</t> and SK‐MEL‐2 cells using morphological, positional, geometric, phaseshift, roughness, and texture parameters. The K‐Means Elbow Plot (A) characterizes the optimal number of data clusters within the melanocyte and SK‐MEL‐2 data sets, as demonstrated by the “elbow” in the plot. The Hierarchical Clustering Dendrogram (B) visualizes the clustering of data points based on their similarity. The great height difference before breaking into two branches demonstrates a great difference between the two cell lines. These findings from the K‐Means Elbow Plot and Hierarchical Clustering Dendrograms suggest that the selected features highlight the differences between melanocytes and SK‐MEL‐2 cells. The plots were visualized using R (version 4.0.5). Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.
Pcs 200 013, supplied by LGC Standards, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pcs-200-013/product/LGC Standards
Average 95 stars, based on 1 article reviews
pcs-200-013 - by Bioz Stars, 2026-02
95/100 stars
  Buy from Supplier

Image Search Results


K‐Means Elbow Plot and Hierarchical Clustering Dendrogram comparing melanocytes and SK‐MEL‐2 cells using morphological, positional, geometric, phaseshift, roughness, and texture parameters. The K‐Means Elbow Plot (A) characterizes the optimal number of data clusters within the melanocyte and SK‐MEL‐2 data sets, as demonstrated by the “elbow” in the plot. The Hierarchical Clustering Dendrogram (B) visualizes the clustering of data points based on their similarity. The great height difference before breaking into two branches demonstrates a great difference between the two cell lines. These findings from the K‐Means Elbow Plot and Hierarchical Clustering Dendrograms suggest that the selected features highlight the differences between melanocytes and SK‐MEL‐2 cells. The plots were visualized using R (version 4.0.5). Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Journal: Cell Biochemistry and Function

Article Title: Morphological and Optical Characterization of NRAS‐Mutant Melanoma Cells and Primary Melanocytes via Quantitative Phase Imaging With Digital Holographic Microscopy

doi: 10.1002/cbf.70156

Figure Lengend Snippet: K‐Means Elbow Plot and Hierarchical Clustering Dendrogram comparing melanocytes and SK‐MEL‐2 cells using morphological, positional, geometric, phaseshift, roughness, and texture parameters. The K‐Means Elbow Plot (A) characterizes the optimal number of data clusters within the melanocyte and SK‐MEL‐2 data sets, as demonstrated by the “elbow” in the plot. The Hierarchical Clustering Dendrogram (B) visualizes the clustering of data points based on their similarity. The great height difference before breaking into two branches demonstrates a great difference between the two cell lines. These findings from the K‐Means Elbow Plot and Hierarchical Clustering Dendrograms suggest that the selected features highlight the differences between melanocytes and SK‐MEL‐2 cells. The plots were visualized using R (version 4.0.5). Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Article Snippet: Primary epidermal melanocytes (HEMa, ATCC PCS‐200‐013) were cultured in a medium consisting of Dermal Cell Basal Medium (ATCC PCS‐200‐030) and the Adult Melanocyte Growth Kit (ATCC PCS‐200‐042) at 37°C with 5% CO 2 .

Techniques:

Violin plots of morphological features for melanocytes versus SK‐MEL‐2 melanoma cells. The melanocytes exhibited smaller, less polarized distributions of (A) average areas, (B) boxed breadth, and (C) boxed length, suggesting smaller areas with narrower sets of dimensions than SK‐MEL‐2 cells. The SK‐MEL‐2 cells exhibited similar values to the melanocytes, however, in (D) eccentricity and (E) hull convexity, suggesting similar elongation with convex shapes. The melanocytes exhibited greater (F) irregular boundaries with lower (G) optical volumes, (H) perimeter lengths, and (I) shape convexities. Additionally, melanocytes exhibited lower, more concentrated (J) optical path length avg, (K) optical path length max, (L) optical thickness avg, and (M) optical thickness max, indicating smaller thicknesses and path lengths than the SK‐MEL‐2 cells. Melanocytes are represented in the color blue, and SK‐MEL‐2 cells are visualized in the color orange. The plots were generated in R (version 4.4.0), and the statistical significance was indicated as **** for p < 0.0001 comparing the two cell lines. Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Journal: Cell Biochemistry and Function

Article Title: Morphological and Optical Characterization of NRAS‐Mutant Melanoma Cells and Primary Melanocytes via Quantitative Phase Imaging With Digital Holographic Microscopy

doi: 10.1002/cbf.70156

Figure Lengend Snippet: Violin plots of morphological features for melanocytes versus SK‐MEL‐2 melanoma cells. The melanocytes exhibited smaller, less polarized distributions of (A) average areas, (B) boxed breadth, and (C) boxed length, suggesting smaller areas with narrower sets of dimensions than SK‐MEL‐2 cells. The SK‐MEL‐2 cells exhibited similar values to the melanocytes, however, in (D) eccentricity and (E) hull convexity, suggesting similar elongation with convex shapes. The melanocytes exhibited greater (F) irregular boundaries with lower (G) optical volumes, (H) perimeter lengths, and (I) shape convexities. Additionally, melanocytes exhibited lower, more concentrated (J) optical path length avg, (K) optical path length max, (L) optical thickness avg, and (M) optical thickness max, indicating smaller thicknesses and path lengths than the SK‐MEL‐2 cells. Melanocytes are represented in the color blue, and SK‐MEL‐2 cells are visualized in the color orange. The plots were generated in R (version 4.4.0), and the statistical significance was indicated as **** for p < 0.0001 comparing the two cell lines. Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Article Snippet: Primary epidermal melanocytes (HEMa, ATCC PCS‐200‐013) were cultured in a medium consisting of Dermal Cell Basal Medium (ATCC PCS‐200‐030) and the Adult Melanocyte Growth Kit (ATCC PCS‐200‐042) at 37°C with 5% CO 2 .

Techniques: Generated

Violin plots of positional and geometric parameters for melanocytes versus SK‐MEL‐2 cells. The SK‐MEL‐2 cells exhibited more distributed values across the (A) boxed center position X and (B) Y; (C) centroid position X and (D) Y; and (E) peak position X and (F) Y, suggesting greater variation in the location of the geometric center and center of mass. Melanocytes are represented in the color blue, and SK‐MEL‐2 cells are visualized in the color orange. The plots were generated in R (version 4.4.0), and the statistical significance was indicated as **** for p < 0.0001 comparing the two cell lines. Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Journal: Cell Biochemistry and Function

Article Title: Morphological and Optical Characterization of NRAS‐Mutant Melanoma Cells and Primary Melanocytes via Quantitative Phase Imaging With Digital Holographic Microscopy

doi: 10.1002/cbf.70156

Figure Lengend Snippet: Violin plots of positional and geometric parameters for melanocytes versus SK‐MEL‐2 cells. The SK‐MEL‐2 cells exhibited more distributed values across the (A) boxed center position X and (B) Y; (C) centroid position X and (D) Y; and (E) peak position X and (F) Y, suggesting greater variation in the location of the geometric center and center of mass. Melanocytes are represented in the color blue, and SK‐MEL‐2 cells are visualized in the color orange. The plots were generated in R (version 4.4.0), and the statistical significance was indicated as **** for p < 0.0001 comparing the two cell lines. Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Article Snippet: Primary epidermal melanocytes (HEMa, ATCC PCS‐200‐013) were cultured in a medium consisting of Dermal Cell Basal Medium (ATCC PCS‐200‐030) and the Adult Melanocyte Growth Kit (ATCC PCS‐200‐042) at 37°C with 5% CO 2 .

Techniques: Generated

Violin plots of phaseshift and roughness parameters for melanocytes versus SK‐MEL‐2 cells. The SK‐MEL‐2 cells exhibited greater, more distributed values for (A) phaseshift avg, (B) phaseshift std. dev, and (C) phaseshift sum, indicating greater phase shifts. The melanocytes exhibited greater (D) roughness avg, suggesting rougher surfaces compared to the SK‐MEL‐2 cells. Melanocytes are represented in the color blue, and SK‐MEL‐2 cells are visualized in the color orange. The plots were generated in R (version 4.4.0), and the statistical significance was indicated as **** for p < 0.0001 comparing the two cell lines. Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Journal: Cell Biochemistry and Function

Article Title: Morphological and Optical Characterization of NRAS‐Mutant Melanoma Cells and Primary Melanocytes via Quantitative Phase Imaging With Digital Holographic Microscopy

doi: 10.1002/cbf.70156

Figure Lengend Snippet: Violin plots of phaseshift and roughness parameters for melanocytes versus SK‐MEL‐2 cells. The SK‐MEL‐2 cells exhibited greater, more distributed values for (A) phaseshift avg, (B) phaseshift std. dev, and (C) phaseshift sum, indicating greater phase shifts. The melanocytes exhibited greater (D) roughness avg, suggesting rougher surfaces compared to the SK‐MEL‐2 cells. Melanocytes are represented in the color blue, and SK‐MEL‐2 cells are visualized in the color orange. The plots were generated in R (version 4.4.0), and the statistical significance was indicated as **** for p < 0.0001 comparing the two cell lines. Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Article Snippet: Primary epidermal melanocytes (HEMa, ATCC PCS‐200‐013) were cultured in a medium consisting of Dermal Cell Basal Medium (ATCC PCS‐200‐030) and the Adult Melanocyte Growth Kit (ATCC PCS‐200‐042) at 37°C with 5% CO 2 .

Techniques: Generated

Violin plots of texture parameters for melanocytes versus SK‐MEL‐2 cells. The melanocytes exhibited greater, more concentrated values in (A) texture clustershade, but lower values in (B) texture clustertendency. The SK‐MEL‐2 cells exhibited lower (C) texture contrast but greater (D) texture correlation and (E) texture energy, suggesting greater uniformity in image texture. Additionally, the melanocytes exhibited greater (F) texture entropy but smaller (G) texture max. prob. and (H) texture homogeneity, suggesting more melanocyte nonuniformity and complexity. The plots were visualized in R (version 4.4.0), with melanocytes in blue and SK‐MEL‐2 cells in orange. Statistical significance was indicated as **** for p < 0.0001 comparing the two cell lines. Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Journal: Cell Biochemistry and Function

Article Title: Morphological and Optical Characterization of NRAS‐Mutant Melanoma Cells and Primary Melanocytes via Quantitative Phase Imaging With Digital Holographic Microscopy

doi: 10.1002/cbf.70156

Figure Lengend Snippet: Violin plots of texture parameters for melanocytes versus SK‐MEL‐2 cells. The melanocytes exhibited greater, more concentrated values in (A) texture clustershade, but lower values in (B) texture clustertendency. The SK‐MEL‐2 cells exhibited lower (C) texture contrast but greater (D) texture correlation and (E) texture energy, suggesting greater uniformity in image texture. Additionally, the melanocytes exhibited greater (F) texture entropy but smaller (G) texture max. prob. and (H) texture homogeneity, suggesting more melanocyte nonuniformity and complexity. The plots were visualized in R (version 4.4.0), with melanocytes in blue and SK‐MEL‐2 cells in orange. Statistical significance was indicated as **** for p < 0.0001 comparing the two cell lines. Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Article Snippet: Primary epidermal melanocytes (HEMa, ATCC PCS‐200‐013) were cultured in a medium consisting of Dermal Cell Basal Medium (ATCC PCS‐200‐030) and the Adult Melanocyte Growth Kit (ATCC PCS‐200‐042) at 37°C with 5% CO 2 .

Techniques:

PCA and t‐SNE plots comparing melanocytes and SK‐MEL‐2 cells using morphological, positional, geometric, phaseshift, roughness, and texture parameters. The PCA plot (A) simplifies and separates the data across the first two principal components (PC1, PC2), visualizing variance while maintaining the global structure of the data. The t‐SNE plot (B) simplifies the high‐dimensional data and visualizes it across the two t‐SNE axes, maintaining the local structure of the data to a greater degree than the PCA plot. The clear separation between the melanocyte and SK‐MEL‐2 clusters in both the PCA and t‐SNE plots suggests significant differences between the two cell lines in terms of the parameters measured. The plots were generated in Python. Melanocytes are represented in the color blue, and SK‐MEL‐2 cells are visualized in the color orange. Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Journal: Cell Biochemistry and Function

Article Title: Morphological and Optical Characterization of NRAS‐Mutant Melanoma Cells and Primary Melanocytes via Quantitative Phase Imaging With Digital Holographic Microscopy

doi: 10.1002/cbf.70156

Figure Lengend Snippet: PCA and t‐SNE plots comparing melanocytes and SK‐MEL‐2 cells using morphological, positional, geometric, phaseshift, roughness, and texture parameters. The PCA plot (A) simplifies and separates the data across the first two principal components (PC1, PC2), visualizing variance while maintaining the global structure of the data. The t‐SNE plot (B) simplifies the high‐dimensional data and visualizes it across the two t‐SNE axes, maintaining the local structure of the data to a greater degree than the PCA plot. The clear separation between the melanocyte and SK‐MEL‐2 clusters in both the PCA and t‐SNE plots suggests significant differences between the two cell lines in terms of the parameters measured. The plots were generated in Python. Melanocytes are represented in the color blue, and SK‐MEL‐2 cells are visualized in the color orange. Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Article Snippet: Primary epidermal melanocytes (HEMa, ATCC PCS‐200‐013) were cultured in a medium consisting of Dermal Cell Basal Medium (ATCC PCS‐200‐030) and the Adult Melanocyte Growth Kit (ATCC PCS‐200‐042) at 37°C with 5% CO 2 .

Techniques: Generated

Ranked Feature Importance Diagram in differentiating melanocytes from SK‐MEL‐2 cells based on the Random Forest model. The Ranked Feature Importance Diagram reveals the parameters most significant in differentiating between the melanocytes and SK‐MEL‐2 cells. The optical parameters were demonstrated as the most significant, while the roughness parameters were the least significant. The diagram was generated using R (version 4.0.5). Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Journal: Cell Biochemistry and Function

Article Title: Morphological and Optical Characterization of NRAS‐Mutant Melanoma Cells and Primary Melanocytes via Quantitative Phase Imaging With Digital Holographic Microscopy

doi: 10.1002/cbf.70156

Figure Lengend Snippet: Ranked Feature Importance Diagram in differentiating melanocytes from SK‐MEL‐2 cells based on the Random Forest model. The Ranked Feature Importance Diagram reveals the parameters most significant in differentiating between the melanocytes and SK‐MEL‐2 cells. The optical parameters were demonstrated as the most significant, while the roughness parameters were the least significant. The diagram was generated using R (version 4.0.5). Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Article Snippet: Primary epidermal melanocytes (HEMa, ATCC PCS‐200‐013) were cultured in a medium consisting of Dermal Cell Basal Medium (ATCC PCS‐200‐030) and the Adult Melanocyte Growth Kit (ATCC PCS‐200‐042) at 37°C with 5% CO 2 .

Techniques: Generated

Mean area, volume, and diameter of melanocytes versus SK‐MEL‐2 cells over 48 h. Bar graphs highlighted the general increase in SK‐MEL‐2 (A) mean cell area, (B) mean cell volume, and (C) mean cell diameter at 0, 12, 24, 36, and 48 h, while the melanocytes remained relatively consistent. Melanocytes are represented in the color blue, and SK‐MEL‐2 cells are visualized in the color orange. The plots were generated in R (version 4.4.0). Error bars represent the standard deviation of the measurements, exhibiting variability and possible significance across the parameters measured. Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Journal: Cell Biochemistry and Function

Article Title: Morphological and Optical Characterization of NRAS‐Mutant Melanoma Cells and Primary Melanocytes via Quantitative Phase Imaging With Digital Holographic Microscopy

doi: 10.1002/cbf.70156

Figure Lengend Snippet: Mean area, volume, and diameter of melanocytes versus SK‐MEL‐2 cells over 48 h. Bar graphs highlighted the general increase in SK‐MEL‐2 (A) mean cell area, (B) mean cell volume, and (C) mean cell diameter at 0, 12, 24, 36, and 48 h, while the melanocytes remained relatively consistent. Melanocytes are represented in the color blue, and SK‐MEL‐2 cells are visualized in the color orange. The plots were generated in R (version 4.4.0). Error bars represent the standard deviation of the measurements, exhibiting variability and possible significance across the parameters measured. Analysis included 21,908 melanocyte measurements and 21,908 SK‐MEL‐2 measurements.

Article Snippet: Primary epidermal melanocytes (HEMa, ATCC PCS‐200‐013) were cultured in a medium consisting of Dermal Cell Basal Medium (ATCC PCS‐200‐030) and the Adult Melanocyte Growth Kit (ATCC PCS‐200‐042) at 37°C with 5% CO 2 .

Techniques: Generated, Standard Deviation