IC013P Search Results


igg2b isotype control  (R&D Systems)
94
R&D Systems igg2b isotype control
a. Western blot analysis of signalling pathways in iPS-derived myeloid progenitor cells following TREM2 activation with TREM2 antibody crosslinking, or <t>IgG</t> control, in control and TREM2 R47H het patient lines. b. Quantification of pSYK, pERK1/2 and pAKT protein normalised to beta-actin; data are mean ± SEM, n=3-6 cell lines from 3 individual experiments, * P <0.05 (two-way ANOVA with Tukey’s correction), ns, non-significant.
Igg2b Isotype Control, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/IC013P/bio_rxiv__2020__09__08__288043-115-13-18?v=R%26D+Systems
Average 94 stars, based on 1 article reviews
igg2b isotype control - by Bioz Stars, 2026-07
94/100 stars
  Buy from Supplier
anti igg2b pe conjugated antibody  (R&D Systems)
92
R&D Systems anti igg2b pe conjugated antibody
a. Western blot analysis of signalling pathways in iPS-derived myeloid progenitor cells following TREM2 activation with TREM2 antibody crosslinking, or <t>IgG</t> control, in control and TREM2 R47H het patient lines. b. Quantification of pSYK, pERK1/2 and pAKT protein normalised to beta-actin; data are mean ± SEM, n=3-6 cell lines from 3 individual experiments, * P <0.05 (two-way ANOVA with Tukey’s correction), ns, non-significant.
Anti Igg2b Pe Conjugated Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/IC013P/pmc11469162-290-7-13?v=R%26D+Systems
Average 92 stars, based on 1 article reviews
anti igg2b pe conjugated antibody - by Bioz Stars, 2026-07
92/100 stars
  Buy from Supplier

Image Search Results


a. Western blot analysis of signalling pathways in iPS-derived myeloid progenitor cells following TREM2 activation with TREM2 antibody crosslinking, or IgG control, in control and TREM2 R47H het patient lines. b. Quantification of pSYK, pERK1/2 and pAKT protein normalised to beta-actin; data are mean ± SEM, n=3-6 cell lines from 3 individual experiments, * P <0.05 (two-way ANOVA with Tukey’s correction), ns, non-significant.

Journal: bioRxiv

Article Title: Microglial signalling pathway deficits associated with the R47H TREM2 variant linked to AD indicate inability to activate inflammasome

doi: 10.1101/2020.09.08.288043

Figure Lengend Snippet: a. Western blot analysis of signalling pathways in iPS-derived myeloid progenitor cells following TREM2 activation with TREM2 antibody crosslinking, or IgG control, in control and TREM2 R47H het patient lines. b. Quantification of pSYK, pERK1/2 and pAKT protein normalised to beta-actin; data are mean ± SEM, n=3-6 cell lines from 3 individual experiments, * P <0.05 (two-way ANOVA with Tukey’s correction), ns, non-significant.

Article Snippet: Myeloid progenitor cells were treated in suspension for 1 h with 5μg of IgG2B isotype control (clone 141945; R&D Systems) or αTREM2 (rat clone 237920; R&D Systems) before being treated with 10μg F(ab’)2 (Jackson #712006153) for 2 min of crosslinking.

Techniques: Western Blot, Derivative Assay, Activation Assay, Control