HM2401 Search Results


90
Hycult Biotech human plasma
Human Plasma, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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86
Hycult Biotech in house biotinylated mouse anti human h ficolin
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91
Hycult Biotech complement c3b ic3b c3d
Protective effects of pravastatin. Glomerular lesions were evaluated by immunohistochemistry. The glomerular lesions observed during and after preeclampsia (PE), characterized by increased tissue factor, fibrin, and complement <t>C3b/iC3b/C3d</t> expression/deposition are focal, and within the affected glomeruli, the pathological markers are global. Collagen deposition and α-smooth muscle actin (ASMA) expression in the glomeruli from mothers after PE are also focal and global. Representative images of the affected glomeruli are shown. (A) Immunohistochemical (IHC) detection of tissue factor, fibrin, and complement activation product C3b/iC3b/C3d in glomeruli from maternal kidneys harvested before, during, and after pregnancy in control mice, PE mice, and PE+PRAV mice. Scale bar: 20 μm. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. (B) IHC detection of collagen I (red fluorescence) and ASMA (green fluorescence) staining in maternal kidneys after normal pregnancies (control) and preeclamptic pregnancies (untreated [PE] and treated with pravastatin [PE+PRAV]). Scale bar: 50 μm. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. (C) Quantification of IHC staining of tissue factor, fibrin, and C3b/iC3b/C3d and collagen I and ASMA using ImageJ. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. Red squares represent the mean. Comparisons between groups were performed by 1-way ANOVA with Bonferroni’s post hoc test.*P < 0.01, statistically different from control at same time.
Complement C3b Ic3b C3d, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 91 stars, based on 1 article reviews
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86
Hycult Biotech anti masp2
Protective effects of pravastatin. Glomerular lesions were evaluated by immunohistochemistry. The glomerular lesions observed during and after preeclampsia (PE), characterized by increased tissue factor, fibrin, and complement <t>C3b/iC3b/C3d</t> expression/deposition are focal, and within the affected glomeruli, the pathological markers are global. Collagen deposition and α-smooth muscle actin (ASMA) expression in the glomeruli from mothers after PE are also focal and global. Representative images of the affected glomeruli are shown. (A) Immunohistochemical (IHC) detection of tissue factor, fibrin, and complement activation product C3b/iC3b/C3d in glomeruli from maternal kidneys harvested before, during, and after pregnancy in control mice, PE mice, and PE+PRAV mice. Scale bar: 20 μm. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. (B) IHC detection of collagen I (red fluorescence) and ASMA (green fluorescence) staining in maternal kidneys after normal pregnancies (control) and preeclamptic pregnancies (untreated [PE] and treated with pravastatin [PE+PRAV]). Scale bar: 50 μm. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. (C) Quantification of IHC staining of tissue factor, fibrin, and C3b/iC3b/C3d and collagen I and ASMA using ImageJ. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. Red squares represent the mean. Comparisons between groups were performed by 1-way ANOVA with Bonferroni’s post hoc test.*P < 0.01, statistically different from control at same time.
Anti Masp2, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti masp2/product/Hycult Biotech
Average 86 stars, based on 1 article reviews
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90
METTLER TOLEDO potentiometer mettler lab hm240
Protective effects of pravastatin. Glomerular lesions were evaluated by immunohistochemistry. The glomerular lesions observed during and after preeclampsia (PE), characterized by increased tissue factor, fibrin, and complement <t>C3b/iC3b/C3d</t> expression/deposition are focal, and within the affected glomeruli, the pathological markers are global. Collagen deposition and α-smooth muscle actin (ASMA) expression in the glomeruli from mothers after PE are also focal and global. Representative images of the affected glomeruli are shown. (A) Immunohistochemical (IHC) detection of tissue factor, fibrin, and complement activation product C3b/iC3b/C3d in glomeruli from maternal kidneys harvested before, during, and after pregnancy in control mice, PE mice, and PE+PRAV mice. Scale bar: 20 μm. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. (B) IHC detection of collagen I (red fluorescence) and ASMA (green fluorescence) staining in maternal kidneys after normal pregnancies (control) and preeclamptic pregnancies (untreated [PE] and treated with pravastatin [PE+PRAV]). Scale bar: 50 μm. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. (C) Quantification of IHC staining of tissue factor, fibrin, and C3b/iC3b/C3d and collagen I and ASMA using ImageJ. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. Red squares represent the mean. Comparisons between groups were performed by 1-way ANOVA with Bonferroni’s post hoc test.*P < 0.01, statistically different from control at same time.
Potentiometer Mettler Lab Hm240, supplied by METTLER TOLEDO, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/potentiometer mettler lab hm240/product/METTLER TOLEDO
Average 90 stars, based on 1 article reviews
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Image Search Results


Protective effects of pravastatin. Glomerular lesions were evaluated by immunohistochemistry. The glomerular lesions observed during and after preeclampsia (PE), characterized by increased tissue factor, fibrin, and complement C3b/iC3b/C3d expression/deposition are focal, and within the affected glomeruli, the pathological markers are global. Collagen deposition and α-smooth muscle actin (ASMA) expression in the glomeruli from mothers after PE are also focal and global. Representative images of the affected glomeruli are shown. (A) Immunohistochemical (IHC) detection of tissue factor, fibrin, and complement activation product C3b/iC3b/C3d in glomeruli from maternal kidneys harvested before, during, and after pregnancy in control mice, PE mice, and PE+PRAV mice. Scale bar: 20 μm. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. (B) IHC detection of collagen I (red fluorescence) and ASMA (green fluorescence) staining in maternal kidneys after normal pregnancies (control) and preeclamptic pregnancies (untreated [PE] and treated with pravastatin [PE+PRAV]). Scale bar: 50 μm. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. (C) Quantification of IHC staining of tissue factor, fibrin, and C3b/iC3b/C3d and collagen I and ASMA using ImageJ. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. Red squares represent the mean. Comparisons between groups were performed by 1-way ANOVA with Bonferroni’s post hoc test.*P < 0.01, statistically different from control at same time.

Journal: JCI Insight

Article Title: Pravastatin therapy during preeclampsia prevents long-term adverse health effects in mice

doi: 10.1172/jci.insight.120147

Figure Lengend Snippet: Protective effects of pravastatin. Glomerular lesions were evaluated by immunohistochemistry. The glomerular lesions observed during and after preeclampsia (PE), characterized by increased tissue factor, fibrin, and complement C3b/iC3b/C3d expression/deposition are focal, and within the affected glomeruli, the pathological markers are global. Collagen deposition and α-smooth muscle actin (ASMA) expression in the glomeruli from mothers after PE are also focal and global. Representative images of the affected glomeruli are shown. (A) Immunohistochemical (IHC) detection of tissue factor, fibrin, and complement activation product C3b/iC3b/C3d in glomeruli from maternal kidneys harvested before, during, and after pregnancy in control mice, PE mice, and PE+PRAV mice. Scale bar: 20 μm. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. (B) IHC detection of collagen I (red fluorescence) and ASMA (green fluorescence) staining in maternal kidneys after normal pregnancies (control) and preeclamptic pregnancies (untreated [PE] and treated with pravastatin [PE+PRAV]). Scale bar: 50 μm. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. (C) Quantification of IHC staining of tissue factor, fibrin, and C3b/iC3b/C3d and collagen I and ASMA using ImageJ. Five to six images per experimental group (n = 6–7 mice/group) and ten glomeruli per slide were analyzed. Red squares represent the mean. Comparisons between groups were performed by 1-way ANOVA with Bonferroni’s post hoc test.*P < 0.01, statistically different from control at same time.

Article Snippet: Kidney cryostatic sections (5 μm) were then incubated with primary antibodies directed to mouse fibrinogen/fibrin (Abcam, ab34269), tissue factor (Abcam, ab151748), and complement C3b/iC3b/C3d (Hycult Biotech, mAb 3/26) followed by incubation with specific secondary IgG antibodies conjugated with FITC (Abcam).

Techniques: Immunohistochemistry, Expressing, Immunohistochemical staining, Activation Assay, Fluorescence, Staining