HM1076 Search Results


mouse anti c5ar  (Hycult Biotech)
92
Hycult Biotech mouse anti c5ar
HT decreases systemic and brain complement expression in neonatal HIE. Whole brain C1q levels in NT animals were significantly higher than HT treated animals at 8, 12, and 24 h after the initial insult (a) . There were no significant differences in the expression of whole brain C3aR (b) or <t>C5aR</t> (c) between NT and HT treated groups. C1q levels in the plasma of NT animals were significantly higher than HT treated animals at 8, 12, and 24 h after injury (d) . Systemic C3a (b) and C5a (c) levels in NT animals were significantly higher than HT treated animals at 12 and 24 after injury. The differences in C5a persisted out to 48 h. ( n = 7 animals per group, solid lines/white bars – NT; dotted lines/gray bars – HT; error bars denote ±SD, * denotes P < 0.05).
Mouse Anti C5ar, supplied by Hycult Biotech, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 92 stars, based on 1 article reviews
mouse anti c5ar - by Bioz Stars, 2025-05
92/100 stars
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HT decreases systemic and brain complement expression in neonatal HIE. Whole brain C1q levels in NT animals were significantly higher than HT treated animals at 8, 12, and 24 h after the initial insult (a) . There were no significant differences in the expression of whole brain C3aR (b) or C5aR (c) between NT and HT treated groups. C1q levels in the plasma of NT animals were significantly higher than HT treated animals at 8, 12, and 24 h after injury (d) . Systemic C3a (b) and C5a (c) levels in NT animals were significantly higher than HT treated animals at 12 and 24 after injury. The differences in C5a persisted out to 48 h. ( n = 7 animals per group, solid lines/white bars – NT; dotted lines/gray bars – HT; error bars denote ±SD, * denotes P < 0.05).

Journal: Frontiers in Neuroscience

Article Title: Therapeutic Hypothermia Inhibits the Classical Complement Pathway in a Rat Model of Neonatal Hypoxic-Ischemic Encephalopathy

doi: 10.3389/fnins.2021.616734

Figure Lengend Snippet: HT decreases systemic and brain complement expression in neonatal HIE. Whole brain C1q levels in NT animals were significantly higher than HT treated animals at 8, 12, and 24 h after the initial insult (a) . There were no significant differences in the expression of whole brain C3aR (b) or C5aR (c) between NT and HT treated groups. C1q levels in the plasma of NT animals were significantly higher than HT treated animals at 8, 12, and 24 h after injury (d) . Systemic C3a (b) and C5a (c) levels in NT animals were significantly higher than HT treated animals at 12 and 24 after injury. The differences in C5a persisted out to 48 h. ( n = 7 animals per group, solid lines/white bars – NT; dotted lines/gray bars – HT; error bars denote ±SD, * denotes P < 0.05).

Article Snippet: The membrane was blocked with 10% normal goat serum (NGS) in PBS, followed by probing with rabbit anti-C3aR (Bioss Inc., Woburn, MA, United States) or Mouse anti-C5aR (Hycult Biotech., Plymouth Meeting, PA, United States), followed by a 1:5000 goat anti-rabbit IRDye 800 secondary antibody.

Techniques: Expressing