This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the

This gene encodes a member of the RSK (ribosomal s6 kinase) family of serine/threonine kinases. This kinase phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase

AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian

The Human Mouse Rat GRP78 HSPA5 Antibody from R D Systems is a goat polyclonal antibody to GRP78 HSPA5 This antibody reacts with human mouse rat The Human Mouse Rat GRP78 HSPA5 Antibody has been

RB1 likely acts as a regulator of other genes. It forms a complex with adenovirus E1A and with SV40 large T antigen, acts as a tumor suppressor, and may bind and modulate functionally certain cellular

TrkA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase

The Human/Mouse/Rat GRP78/HSPA5 Antibody from R&D Systems is a GRP78/HSPA5 antibody to GRP78/HSPA5. This antibody reacts with Human, Mouse, Rat. The GRP78/HSPA5 antibody has been validated for the following applications: Western Blot, Simple Western.

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.