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  • 91
    Millipore antibody alm 006
    Antibody Alm 006, supplied by Millipore, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/antibody alm 006/product/Millipore
    Average 91 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    antibody alm 006 - by Bioz Stars, 2022-08
    91/100 stars
      Buy from Supplier

    92
    Alomone Labs anti ngf prongf
    Anti Ngf Prongf, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti ngf prongf/product/Alomone Labs
    Average 92 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti ngf prongf - by Bioz Stars, 2022-08
    92/100 stars
      Buy from Supplier

    94
    Alomone Labs ngf neutralizing antibody
    <t>ENT-A013,</t> ENT-A013E and ENT-A013Z protect PC12 cells against serum deprivation-induced cell death in a TrkA-dependent manner. PC12 cells were starved of serum and treated with <t>NGF,</t> ENT-A013, ENT-A013E, ENT-A013Z or vehicle in the presence or absence of a specific TrkA inhibitor GW441756 for 24 h and CellTox assay was used to quantify cell death. CellTox positive cell number was normalized to total Hoescht positive cell number in each image. Representative images from 4–9 independent experiments are shown ( A ) and quantification ( B ). Data represent ±SEM. One-way ANOVA, Tukey’s test correction: ns: non-significant; * and # p
    Ngf Neutralizing Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ngf neutralizing antibody/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    ngf neutralizing antibody - by Bioz Stars, 2022-08
    94/100 stars
      Buy from Supplier

    Image Search Results


    ENT-A013, ENT-A013E and ENT-A013Z protect PC12 cells against serum deprivation-induced cell death in a TrkA-dependent manner. PC12 cells were starved of serum and treated with NGF, ENT-A013, ENT-A013E, ENT-A013Z or vehicle in the presence or absence of a specific TrkA inhibitor GW441756 for 24 h and CellTox assay was used to quantify cell death. CellTox positive cell number was normalized to total Hoescht positive cell number in each image. Representative images from 4–9 independent experiments are shown ( A ) and quantification ( B ). Data represent ±SEM. One-way ANOVA, Tukey’s test correction: ns: non-significant; * and # p

    Journal: Biomedicines

    Article Title: Development and Biological Characterization of a Novel Selective TrkA Agonist with Neuroprotective Properties against Amyloid Toxicity

    doi: 10.3390/biomedicines10030614

    Figure Lengend Snippet: ENT-A013, ENT-A013E and ENT-A013Z protect PC12 cells against serum deprivation-induced cell death in a TrkA-dependent manner. PC12 cells were starved of serum and treated with NGF, ENT-A013, ENT-A013E, ENT-A013Z or vehicle in the presence or absence of a specific TrkA inhibitor GW441756 for 24 h and CellTox assay was used to quantify cell death. CellTox positive cell number was normalized to total Hoescht positive cell number in each image. Representative images from 4–9 independent experiments are shown ( A ) and quantification ( B ). Data represent ±SEM. One-way ANOVA, Tukey’s test correction: ns: non-significant; * and # p

    Article Snippet: For neurite outgrowth assay, cells were cultured for 5 days in vitro with medium deprived of NGF in the presence of ENT-A013 (500 nM, every 48 h), along with NGF-neutralizing antibody.

    Techniques:

    Docking poses of the two ENT-A013 isomers, ENT-A013E and ENT-A013Z, in sites 1a and 1b at the two symmetry-related TrkA-D5—NGF interfaces of the neurotrophin-receptor complex. The close-up views show residues lining the two sites. TrkA-D5 and NGF are shown in green and blue cartoon representation, respectively, with selected residues in stick representation colored by atom type. The compounds are shown in orange stick representation.

    Journal: Biomedicines

    Article Title: Development and Biological Characterization of a Novel Selective TrkA Agonist with Neuroprotective Properties against Amyloid Toxicity

    doi: 10.3390/biomedicines10030614

    Figure Lengend Snippet: Docking poses of the two ENT-A013 isomers, ENT-A013E and ENT-A013Z, in sites 1a and 1b at the two symmetry-related TrkA-D5—NGF interfaces of the neurotrophin-receptor complex. The close-up views show residues lining the two sites. TrkA-D5 and NGF are shown in green and blue cartoon representation, respectively, with selected residues in stick representation colored by atom type. The compounds are shown in orange stick representation.

    Article Snippet: For neurite outgrowth assay, cells were cultured for 5 days in vitro with medium deprived of NGF in the presence of ENT-A013 (500 nM, every 48 h), along with NGF-neutralizing antibody.

    Techniques: