ACT-014 Search Results


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Alomone Labs primary antibodies octn1
Localization of novel organic cation transporter 1 <t>(OCTN1)</t> in the eye cross-sections. OCTN1 immunoreactivity in anterior (cornea, lens, and ciliary body) and posterior (peripheral and central retina, RPE/Choroid) segments of the eyes of (A,D,G,J,M,P) WT controls, (B,E,H,K,N,Q) non-treated 5XFAD, and (C,F,I,L,O,R) Ergo-treated 5XFAD, respectively are illustrated. (S) OCTN1 labeled whole eye cross-section to illustrates the anterior and posterior segments that were used for pixel count analysis. OCTN1 immunoreactivity in the (T) whole eye, (U) anterior, and (V) posterior segments were compared across the three animal groups and illustrated using scatter plots. White arrowheads indicate OCTN1 labeling in the eye cross-sections. Significance levels of p < 0.05 are indicated as * p < 0.05 and ** p < 0.01. Scale bar, 20 μm; bright green, OCTN1; blue, DAPI. OCTN1, organic novel cation transporter 1; WT, C57BL/6J wildtype; NFL, nerve fiber layer; GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; RPE, retinal pigment epithelium.
Primary Antibodies Octn1, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Localization of novel organic cation transporter 1 (OCTN1) in the eye cross-sections. OCTN1 immunoreactivity in anterior (cornea, lens, and ciliary body) and posterior (peripheral and central retina, RPE/Choroid) segments of the eyes of (A,D,G,J,M,P) WT controls, (B,E,H,K,N,Q) non-treated 5XFAD, and (C,F,I,L,O,R) Ergo-treated 5XFAD, respectively are illustrated. (S) OCTN1 labeled whole eye cross-section to illustrates the anterior and posterior segments that were used for pixel count analysis. OCTN1 immunoreactivity in the (T) whole eye, (U) anterior, and (V) posterior segments were compared across the three animal groups and illustrated using scatter plots. White arrowheads indicate OCTN1 labeling in the eye cross-sections. Significance levels of p < 0.05 are indicated as * p < 0.05 and ** p < 0.01. Scale bar, 20 μm; bright green, OCTN1; blue, DAPI. OCTN1, organic novel cation transporter 1; WT, C57BL/6J wildtype; NFL, nerve fiber layer; GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; RPE, retinal pigment epithelium.

Journal: Frontiers in Neuroscience

Article Title: Ergothioneine, a dietary antioxidant improves amyloid beta clearance in the neuroretina of a mouse model of Alzheimer’s disease

doi: 10.3389/fnins.2023.1107436

Figure Lengend Snippet: Localization of novel organic cation transporter 1 (OCTN1) in the eye cross-sections. OCTN1 immunoreactivity in anterior (cornea, lens, and ciliary body) and posterior (peripheral and central retina, RPE/Choroid) segments of the eyes of (A,D,G,J,M,P) WT controls, (B,E,H,K,N,Q) non-treated 5XFAD, and (C,F,I,L,O,R) Ergo-treated 5XFAD, respectively are illustrated. (S) OCTN1 labeled whole eye cross-section to illustrates the anterior and posterior segments that were used for pixel count analysis. OCTN1 immunoreactivity in the (T) whole eye, (U) anterior, and (V) posterior segments were compared across the three animal groups and illustrated using scatter plots. White arrowheads indicate OCTN1 labeling in the eye cross-sections. Significance levels of p < 0.05 are indicated as * p < 0.05 and ** p < 0.01. Scale bar, 20 μm; bright green, OCTN1; blue, DAPI. OCTN1, organic novel cation transporter 1; WT, C57BL/6J wildtype; NFL, nerve fiber layer; GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; RPE, retinal pigment epithelium.

Article Snippet: In addition to 6E10, GFAP, and IBA1, primary antibodies OCTN1 (rabbit polyclonal, Cat# ACT-014, Alomone Labs), a marker for Ergo transporter and AQP4 (rabbit polyclonal, Cat# AQP-004, Alomone Labs), a major membrane water channel in the CNS were used in the eye cross-sections.

Techniques: Labeling

 OCTN1  expression in the eye cross-sections.

Journal: Frontiers in Neuroscience

Article Title: Ergothioneine, a dietary antioxidant improves amyloid beta clearance in the neuroretina of a mouse model of Alzheimer’s disease

doi: 10.3389/fnins.2023.1107436

Figure Lengend Snippet: OCTN1 expression in the eye cross-sections.

Article Snippet: In addition to 6E10, GFAP, and IBA1, primary antibodies OCTN1 (rabbit polyclonal, Cat# ACT-014, Alomone Labs), a marker for Ergo transporter and AQP4 (rabbit polyclonal, Cat# AQP-004, Alomone Labs), a major membrane water channel in the CNS were used in the eye cross-sections.

Techniques: Expressing