A02275-2 Search Results


anti alox12 a02275  (Boster Bio)
91
Boster Bio anti alox12 a02275
Molecular docking results. (A , B) Schematic diagram of the binding mode of chrysin to <t>ALOX12</t> protein (left panels) and details of the binding pose (right panels). (C , D) Schematic diagram of the binding mode of 7,8-DHF to IKKB protein (left panels) and details of the binding pose (right panels). (E , F) Schematic diagram of the binding mode of DHC to TRPV1 protein (left panels) and details of the binding pose (right panels).
Anti Alox12 A02275, supplied by Boster Bio, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Molecular docking results. (A , B) Schematic diagram of the binding mode of chrysin to ALOX12 protein (left panels) and details of the binding pose (right panels). (C , D) Schematic diagram of the binding mode of 7,8-DHF to IKKB protein (left panels) and details of the binding pose (right panels). (E , F) Schematic diagram of the binding mode of DHC to TRPV1 protein (left panels) and details of the binding pose (right panels).

Journal: Frontiers in Pharmacology

Article Title: Pinelliae rhizoma alleviated acute lung injury induced by lipopolysaccharide via suppressing endoplasmic reticulum stress-mediated NLRP3 inflammasome

doi: 10.3389/fphar.2022.883865

Figure Lengend Snippet: Molecular docking results. (A , B) Schematic diagram of the binding mode of chrysin to ALOX12 protein (left panels) and details of the binding pose (right panels). (C , D) Schematic diagram of the binding mode of 7,8-DHF to IKKB protein (left panels) and details of the binding pose (right panels). (E , F) Schematic diagram of the binding mode of DHC to TRPV1 protein (left panels) and details of the binding pose (right panels).

Article Snippet: Anti- ALOX12 (A02275) was purchased from Boster Biological Technology Co. Ltd. (Wuhan, China).

Techniques: Binding Assay

Validation of the effects of DHC, chrysin, and 7,8-DHF on inflammation-related proteins. RAW264.7 cells were exposed to LPS and treated with DHC, chrysin, or 7,8-DHF for 12 h. (A , B) The effects of DHC on the expressions of TRPV1, NLRP3, Caspase-1, p-NF-κB, Bip, and ATF4 were examined by Western blot ( n = 3). (C , D) The effects of chrysin on the expressions of ALOX12, p-IκBα, IκBα, p-NF-κB, NLRP3, Caspase-1, Bip, and ATF4 were detected by Western blot. ( n = 3). (E , F) Western blot was employed to detect the effects of 7,8-DHF on the expressions of IKKB, p-IκBα, IκBα, p-NF-κB, NLRP3 and Caspase-1 ( n = 3). *p < 0.05 , **p < 0.01 , ***p < 0.001 , ****p < 0.0001 vs. Control groups ; #p < 0.05 , ##p < 0.01 , ###p < 0.001 , ####p < 0.0001 vs. LPS-treated groups.

Journal: Frontiers in Pharmacology

Article Title: Pinelliae rhizoma alleviated acute lung injury induced by lipopolysaccharide via suppressing endoplasmic reticulum stress-mediated NLRP3 inflammasome

doi: 10.3389/fphar.2022.883865

Figure Lengend Snippet: Validation of the effects of DHC, chrysin, and 7,8-DHF on inflammation-related proteins. RAW264.7 cells were exposed to LPS and treated with DHC, chrysin, or 7,8-DHF for 12 h. (A , B) The effects of DHC on the expressions of TRPV1, NLRP3, Caspase-1, p-NF-κB, Bip, and ATF4 were examined by Western blot ( n = 3). (C , D) The effects of chrysin on the expressions of ALOX12, p-IκBα, IκBα, p-NF-κB, NLRP3, Caspase-1, Bip, and ATF4 were detected by Western blot. ( n = 3). (E , F) Western blot was employed to detect the effects of 7,8-DHF on the expressions of IKKB, p-IκBα, IκBα, p-NF-κB, NLRP3 and Caspase-1 ( n = 3). *p < 0.05 , **p < 0.01 , ***p < 0.001 , ****p < 0.0001 vs. Control groups ; #p < 0.05 , ##p < 0.01 , ###p < 0.001 , ####p < 0.0001 vs. LPS-treated groups.

Article Snippet: Anti- ALOX12 (A02275) was purchased from Boster Biological Technology Co. Ltd. (Wuhan, China).

Techniques: Biomarker Discovery, Western Blot, Control