7072 Search Results


virus  (Vector Biolabs)
95
Vector Biolabs virus
Virus, supplied by Vector Biolabs, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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fs41  (DSMZ)
93
DSMZ fs41
Fs41, supplied by DSMZ, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anaerobic p histicola  (DSMZ)
92
DSMZ anaerobic p histicola
P. <t>histicola</t> alleviated the depression-like behaviors in OVX mice. The mice were ovariectomized or sham operated and then given 1 × 109 CFU P. histicola medium per 2 days for 12 weeks. The sham group and OVX group were given the same volume of sterile medium. The depression-like behavior was measured by OFT, EPM, TST, and FST. (A) Schematic diagram of the experimental procedures. (B) Central area time of OFT. (C) Transition times of OFT. (D) Total time in open arms of EPM. (E) Transition times in open arms of EPM. (F) Immobility time of TST. (G) . Immobility time of FST. Data are presented as means ± SEM ( n = 7–8/group). * p < 0.05, ** p < 0.01, **** p < 0.0001.
Anaerobic P Histicola, supplied by DSMZ, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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dsm105107  (DSMZ)
86
DSMZ dsm105107
P. <t>histicola</t> alleviated the depression-like behaviors in OVX mice. The mice were ovariectomized or sham operated and then given 1 × 109 CFU P. histicola medium per 2 days for 12 weeks. The sham group and OVX group were given the same volume of sterile medium. The depression-like behavior was measured by OFT, EPM, TST, and FST. (A) Schematic diagram of the experimental procedures. (B) Central area time of OFT. (C) Transition times of OFT. (D) Total time in open arms of EPM. (E) Transition times in open arms of EPM. (F) Immobility time of TST. (G) . Immobility time of FST. Data are presented as means ± SEM ( n = 7–8/group). * p < 0.05, ** p < 0.01, **** p < 0.0001.
Dsm105107, supplied by DSMZ, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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araldite gt 7072  (Huntsman International LLC)
90
Huntsman International LLC araldite gt 7072
P. <t>histicola</t> alleviated the depression-like behaviors in OVX mice. The mice were ovariectomized or sham operated and then given 1 × 109 CFU P. histicola medium per 2 days for 12 weeks. The sham group and OVX group were given the same volume of sterile medium. The depression-like behavior was measured by OFT, EPM, TST, and FST. (A) Schematic diagram of the experimental procedures. (B) Central area time of OFT. (C) Transition times of OFT. (D) Total time in open arms of EPM. (E) Transition times in open arms of EPM. (F) Immobility time of TST. (G) . Immobility time of FST. Data are presented as means ± SEM ( n = 7–8/group). * p < 0.05, ** p < 0.01, **** p < 0.0001.
Araldite Gt 7072, supplied by Huntsman International LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cyclic aromatic di-functional epoxy resin araldite 7072  (Huntsman International LLC)
90
Huntsman International LLC cyclic aromatic di-functional epoxy resin araldite 7072
P. <t>histicola</t> alleviated the depression-like behaviors in OVX mice. The mice were ovariectomized or sham operated and then given 1 × 109 CFU P. histicola medium per 2 days for 12 weeks. The sham group and OVX group were given the same volume of sterile medium. The depression-like behavior was measured by OFT, EPM, TST, and FST. (A) Schematic diagram of the experimental procedures. (B) Central area time of OFT. (C) Transition times of OFT. (D) Total time in open arms of EPM. (E) Transition times in open arms of EPM. (F) Immobility time of TST. (G) . Immobility time of FST. Data are presented as means ± SEM ( n = 7–8/group). * p < 0.05, ** p < 0.01, **** p < 0.0001.
Cyclic Aromatic Di Functional Epoxy Resin Araldite 7072, supplied by Huntsman International LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ppg sensor sfh 7072  (Osram Sylvania)
90
Osram Sylvania ppg sensor sfh 7072
P. <t>histicola</t> alleviated the depression-like behaviors in OVX mice. The mice were ovariectomized or sham operated and then given 1 × 109 CFU P. histicola medium per 2 days for 12 weeks. The sham group and OVX group were given the same volume of sterile medium. The depression-like behavior was measured by OFT, EPM, TST, and FST. (A) Schematic diagram of the experimental procedures. (B) Central area time of OFT. (C) Transition times of OFT. (D) Total time in open arms of EPM. (E) Transition times in open arms of EPM. (F) Immobility time of TST. (G) . Immobility time of FST. Data are presented as means ± SEM ( n = 7–8/group). * p < 0.05, ** p < 0.01, **** p < 0.0001.
Ppg Sensor Sfh 7072, supplied by Osram Sylvania, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rk-7072 automotive paint  (DuPont de Nemours)
90
DuPont de Nemours rk-7072 automotive paint
P. <t>histicola</t> alleviated the depression-like behaviors in OVX mice. The mice were ovariectomized or sham operated and then given 1 × 109 CFU P. histicola medium per 2 days for 12 weeks. The sham group and OVX group were given the same volume of sterile medium. The depression-like behavior was measured by OFT, EPM, TST, and FST. (A) Schematic diagram of the experimental procedures. (B) Central area time of OFT. (C) Transition times of OFT. (D) Total time in open arms of EPM. (E) Transition times in open arms of EPM. (F) Immobility time of TST. (G) . Immobility time of FST. Data are presented as means ± SEM ( n = 7–8/group). * p < 0.05, ** p < 0.01, **** p < 0.0001.
Rk 7072 Automotive Paint, supplied by DuPont de Nemours, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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kbp-7072  (KBP Biosciences USA Inc)
90
KBP Biosciences USA Inc kbp-7072
P. <t>histicola</t> alleviated the depression-like behaviors in OVX mice. The mice were ovariectomized or sham operated and then given 1 × 109 CFU P. histicola medium per 2 days for 12 weeks. The sham group and OVX group were given the same volume of sterile medium. The depression-like behavior was measured by OFT, EPM, TST, and FST. (A) Schematic diagram of the experimental procedures. (B) Central area time of OFT. (C) Transition times of OFT. (D) Total time in open arms of EPM. (E) Transition times in open arms of EPM. (F) Immobility time of TST. (G) . Immobility time of FST. Data are presented as means ± SEM ( n = 7–8/group). * p < 0.05, ** p < 0.01, **** p < 0.0001.
Kbp 7072, supplied by KBP Biosciences USA Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bisphenol a type epoxy resin gt7072  (VANTICO S R L)
90
VANTICO S R L bisphenol a type epoxy resin gt7072
P. <t>histicola</t> alleviated the depression-like behaviors in OVX mice. The mice were ovariectomized or sham operated and then given 1 × 109 CFU P. histicola medium per 2 days for 12 weeks. The sham group and OVX group were given the same volume of sterile medium. The depression-like behavior was measured by OFT, EPM, TST, and FST. (A) Schematic diagram of the experimental procedures. (B) Central area time of OFT. (C) Transition times of OFT. (D) Total time in open arms of EPM. (E) Transition times in open arms of EPM. (F) Immobility time of TST. (G) . Immobility time of FST. Data are presented as means ± SEM ( n = 7–8/group). * p < 0.05, ** p < 0.01, **** p < 0.0001.
Bisphenol A Type Epoxy Resin Gt7072, supplied by VANTICO S R L, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pigment b15:3 heliogen blue l 7072 d  (BASF)
90
BASF pigment b15:3 heliogen blue l 7072 d
P. <t>histicola</t> alleviated the depression-like behaviors in OVX mice. The mice were ovariectomized or sham operated and then given 1 × 109 CFU P. histicola medium per 2 days for 12 weeks. The sham group and OVX group were given the same volume of sterile medium. The depression-like behavior was measured by OFT, EPM, TST, and FST. (A) Schematic diagram of the experimental procedures. (B) Central area time of OFT. (C) Transition times of OFT. (D) Total time in open arms of EPM. (E) Transition times in open arms of EPM. (F) Immobility time of TST. (G) . Immobility time of FST. Data are presented as means ± SEM ( n = 7–8/group). * p < 0.05, ** p < 0.01, **** p < 0.0001.
Pigment B15:3 Heliogen Blue L 7072 D, supplied by BASF, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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kbp-7072 powder  (KBP BioSciences Co)
90
KBP BioSciences Co kbp-7072 powder
P. <t>histicola</t> alleviated the depression-like behaviors in OVX mice. The mice were ovariectomized or sham operated and then given 1 × 109 CFU P. histicola medium per 2 days for 12 weeks. The sham group and OVX group were given the same volume of sterile medium. The depression-like behavior was measured by OFT, EPM, TST, and FST. (A) Schematic diagram of the experimental procedures. (B) Central area time of OFT. (C) Transition times of OFT. (D) Total time in open arms of EPM. (E) Transition times in open arms of EPM. (F) Immobility time of TST. (G) . Immobility time of FST. Data are presented as means ± SEM ( n = 7–8/group). * p < 0.05, ** p < 0.01, **** p < 0.0001.
Kbp 7072 Powder, supplied by KBP BioSciences Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


P. histicola alleviated the depression-like behaviors in OVX mice. The mice were ovariectomized or sham operated and then given 1 × 109 CFU P. histicola medium per 2 days for 12 weeks. The sham group and OVX group were given the same volume of sterile medium. The depression-like behavior was measured by OFT, EPM, TST, and FST. (A) Schematic diagram of the experimental procedures. (B) Central area time of OFT. (C) Transition times of OFT. (D) Total time in open arms of EPM. (E) Transition times in open arms of EPM. (F) Immobility time of TST. (G) . Immobility time of FST. Data are presented as means ± SEM ( n = 7–8/group). * p < 0.05, ** p < 0.01, **** p < 0.0001.

Journal: Frontiers in Nutrition

Article Title: Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice

doi: 10.3389/fnut.2021.805465

Figure Lengend Snippet: P. histicola alleviated the depression-like behaviors in OVX mice. The mice were ovariectomized or sham operated and then given 1 × 109 CFU P. histicola medium per 2 days for 12 weeks. The sham group and OVX group were given the same volume of sterile medium. The depression-like behavior was measured by OFT, EPM, TST, and FST. (A) Schematic diagram of the experimental procedures. (B) Central area time of OFT. (C) Transition times of OFT. (D) Total time in open arms of EPM. (E) Transition times in open arms of EPM. (F) Immobility time of TST. (G) . Immobility time of FST. Data are presented as means ± SEM ( n = 7–8/group). * p < 0.05, ** p < 0.01, **** p < 0.0001.

Article Snippet: Anaerobic P. histicola (strain number: DSM19854) from Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ) was cultured in modified PYG medium (the media component is shown in ) at 37°C for 24 h under anaerobic conditions.

Techniques: Sterility

P. histicola reduced hippocampal injury and neuronal apoptosis in OVX mice. (A) H & E staining and its quantifications. Magnification 100 × and 400 ×. Scale bar = 20 μm. (B) Nissl staining and its quantifications. Magnification 100 × and 400 ×. Scale bar = 20 μm. (C) Cleaved caspase-3 protein level and the ratio of cleaved caspase-3 to caspase-3 in hippocampus. (D,E) . The mRNA expression of caspase-3 (C) and caspase-8 (D) detected by qRT-PCR. Data are presented as means ± SEM ( n = 4/group). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

Journal: Frontiers in Nutrition

Article Title: Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice

doi: 10.3389/fnut.2021.805465

Figure Lengend Snippet: P. histicola reduced hippocampal injury and neuronal apoptosis in OVX mice. (A) H & E staining and its quantifications. Magnification 100 × and 400 ×. Scale bar = 20 μm. (B) Nissl staining and its quantifications. Magnification 100 × and 400 ×. Scale bar = 20 μm. (C) Cleaved caspase-3 protein level and the ratio of cleaved caspase-3 to caspase-3 in hippocampus. (D,E) . The mRNA expression of caspase-3 (C) and caspase-8 (D) detected by qRT-PCR. Data are presented as means ± SEM ( n = 4/group). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

Article Snippet: Anaerobic P. histicola (strain number: DSM19854) from Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ) was cultured in modified PYG medium (the media component is shown in ) at 37°C for 24 h under anaerobic conditions.

Techniques: Staining, Expressing, Quantitative RT-PCR

P. histicola restored the intestinal flora disorder of OVX mice. (A,B) Alpha diversity index ACE (A) and Chao (B) . (C) PCA on gene level of beta diversity analysis. (D,E) LDA effect size analysis and LDA discrimination results of each level. (F) Intergroup difference test at genus level. (G) The KEGG metabolic pathways of PICRUSt2. Data are presented as means ± SEM ( n = 4/group). **** p < 0.0001.

Journal: Frontiers in Nutrition

Article Title: Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice

doi: 10.3389/fnut.2021.805465

Figure Lengend Snippet: P. histicola restored the intestinal flora disorder of OVX mice. (A,B) Alpha diversity index ACE (A) and Chao (B) . (C) PCA on gene level of beta diversity analysis. (D,E) LDA effect size analysis and LDA discrimination results of each level. (F) Intergroup difference test at genus level. (G) The KEGG metabolic pathways of PICRUSt2. Data are presented as means ± SEM ( n = 4/group). **** p < 0.0001.

Article Snippet: Anaerobic P. histicola (strain number: DSM19854) from Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ) was cultured in modified PYG medium (the media component is shown in ) at 37°C for 24 h under anaerobic conditions.

Techniques:

P. histicola inhibited the activation of intestinal macrophage and downregulated the inflammation factors level in OVX mice. (A) The mRNA expression of MCP-1, IL-6, IL-8, TNF-α in duodenum. (B) The mRNA expression of MCP-1, IL-6, IL-8, TNF-α in jejunum. (C) The mRNA expression of MCP-1, IL-6, IL-8, TNF-α in ileum. (D) The mRNA expression of MCP-1, IL-6, IL-8, TNF-α in colon. (E,F) Immunofluorescence (E) and quantification (F) of colon macrophage marker CD68. Magnification 400 ×. Scale bar = 20 μm. (G) VCAM protein level and the ratio of VCAM to β-Tubulin in colon. Data are presented as means ± SEM ( n = 3–4/group). * p < 0.05 vs. sham, ** p < 0.01 vs. sham, *** p < 0.001 vs. sham, # p < 0.01 vs. OVX, ## p < 0.01 vs. OVX, ### p < 0.001 vs. OVX, #### p < 0.0001 vs. OVX, ns p > 0.05, **** p < 0.0001.

Journal: Frontiers in Nutrition

Article Title: Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice

doi: 10.3389/fnut.2021.805465

Figure Lengend Snippet: P. histicola inhibited the activation of intestinal macrophage and downregulated the inflammation factors level in OVX mice. (A) The mRNA expression of MCP-1, IL-6, IL-8, TNF-α in duodenum. (B) The mRNA expression of MCP-1, IL-6, IL-8, TNF-α in jejunum. (C) The mRNA expression of MCP-1, IL-6, IL-8, TNF-α in ileum. (D) The mRNA expression of MCP-1, IL-6, IL-8, TNF-α in colon. (E,F) Immunofluorescence (E) and quantification (F) of colon macrophage marker CD68. Magnification 400 ×. Scale bar = 20 μm. (G) VCAM protein level and the ratio of VCAM to β-Tubulin in colon. Data are presented as means ± SEM ( n = 3–4/group). * p < 0.05 vs. sham, ** p < 0.01 vs. sham, *** p < 0.001 vs. sham, # p < 0.01 vs. OVX, ## p < 0.01 vs. OVX, ### p < 0.001 vs. OVX, #### p < 0.0001 vs. OVX, ns p > 0.05, **** p < 0.0001.

Article Snippet: Anaerobic P. histicola (strain number: DSM19854) from Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ) was cultured in modified PYG medium (the media component is shown in ) at 37°C for 24 h under anaerobic conditions.

Techniques: Activation Assay, Expressing, Immunofluorescence, Marker

P. histicola restored intestinal leakage in OVX mice. (A) The mRNA expression of ZO-1, occludin, claudin-1, MUC2 in duodenum. (B) The mRNA expression of ZO-1, occludin, claudin-1, MUC2 in the mRNA expression of ZO-1, occludin, claudin-1, MUC2 in jejunum. (C) The mRNA expression of ZO-1, occludin, claudin-1, MUC2 in ileum. (D) The mRNA expression of ZO-1, occludin, claudin-1, MUC2 in colon. (E) Western blotting analysis of occludin in colon. (F) Immunofluorescence of occludin in colon. Magnification 400 ×. Scale bar = 20 μm. (G) Immunofluorescence of ZO-1 in colon. Magnification 400 ×. Scale bar = 20 μm. Data are presented as means ± SEM ( n = 3–4/group). * p < 0.05 vs. sham, ** p < 0.01 vs. sham, *** p < 0.001 vs. sham, # p < 0.01 vs. OVX, ## p < 0.01 vs. OVX, #### p < 0.0001 vs. OVX.

Journal: Frontiers in Nutrition

Article Title: Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice

doi: 10.3389/fnut.2021.805465

Figure Lengend Snippet: P. histicola restored intestinal leakage in OVX mice. (A) The mRNA expression of ZO-1, occludin, claudin-1, MUC2 in duodenum. (B) The mRNA expression of ZO-1, occludin, claudin-1, MUC2 in the mRNA expression of ZO-1, occludin, claudin-1, MUC2 in jejunum. (C) The mRNA expression of ZO-1, occludin, claudin-1, MUC2 in ileum. (D) The mRNA expression of ZO-1, occludin, claudin-1, MUC2 in colon. (E) Western blotting analysis of occludin in colon. (F) Immunofluorescence of occludin in colon. Magnification 400 ×. Scale bar = 20 μm. (G) Immunofluorescence of ZO-1 in colon. Magnification 400 ×. Scale bar = 20 μm. Data are presented as means ± SEM ( n = 3–4/group). * p < 0.05 vs. sham, ** p < 0.01 vs. sham, *** p < 0.001 vs. sham, # p < 0.01 vs. OVX, ## p < 0.01 vs. OVX, #### p < 0.0001 vs. OVX.

Article Snippet: Anaerobic P. histicola (strain number: DSM19854) from Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ) was cultured in modified PYG medium (the media component is shown in ) at 37°C for 24 h under anaerobic conditions.

Techniques: Expressing, Western Blot, Immunofluorescence

P. histicola inhibited the hippocampal inflammation in OVX mice. (A) Immunofluorescence of microglia marker Iba1 of DG area and the quantification of the number and size of Iba1 positive cells. Magnification 400 ×. Scale bar = 20 μm. (B) The ratio of COX-2, TLR4, Myd88 to β-tubulin and p-JNK to JNK in hippocampus. (C) IL-6 mRNA level in hippocampus. (D) IL-8 mRNA level in hippocampus. (E) MCP-1 mRNA level in hippocampus. (F) TNF-α mRNA level in hippocampus. Data are presented as means ± SEM ( n = 3–4/group). * p < 0.05, ** p < 0.01, *** p < 0.001.

Journal: Frontiers in Nutrition

Article Title: Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice

doi: 10.3389/fnut.2021.805465

Figure Lengend Snippet: P. histicola inhibited the hippocampal inflammation in OVX mice. (A) Immunofluorescence of microglia marker Iba1 of DG area and the quantification of the number and size of Iba1 positive cells. Magnification 400 ×. Scale bar = 20 μm. (B) The ratio of COX-2, TLR4, Myd88 to β-tubulin and p-JNK to JNK in hippocampus. (C) IL-6 mRNA level in hippocampus. (D) IL-8 mRNA level in hippocampus. (E) MCP-1 mRNA level in hippocampus. (F) TNF-α mRNA level in hippocampus. Data are presented as means ± SEM ( n = 3–4/group). * p < 0.05, ** p < 0.01, *** p < 0.001.

Article Snippet: Anaerobic P. histicola (strain number: DSM19854) from Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ) was cultured in modified PYG medium (the media component is shown in ) at 37°C for 24 h under anaerobic conditions.

Techniques: Immunofluorescence, Marker

P. histicola increased the level of BDNF for nerve proliferation. (A) 5-HT1A mRNA level in hippocampus. (B) 5-HT1B mRNA level in hippocampus. (C) DA-1 mRNA level in hippocampus. (D) DA-2 mRNA level in hippocampus. (E) BDNF protein level and the ratio of BDNF to β-tubulin in hippocampus. (F) BDNF mRNA level in hippocampus. (G) Immunohistochemistry of hippocampal proliferation marker Ki-67. Magnification 50 × and 400 ×. Scale bar =20 μm. Data are presented as means ± SEM ( n = 3–4/group). * p < 0.05, ** p < 0.01, ns p > 0.05.

Journal: Frontiers in Nutrition

Article Title: Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice

doi: 10.3389/fnut.2021.805465

Figure Lengend Snippet: P. histicola increased the level of BDNF for nerve proliferation. (A) 5-HT1A mRNA level in hippocampus. (B) 5-HT1B mRNA level in hippocampus. (C) DA-1 mRNA level in hippocampus. (D) DA-2 mRNA level in hippocampus. (E) BDNF protein level and the ratio of BDNF to β-tubulin in hippocampus. (F) BDNF mRNA level in hippocampus. (G) Immunohistochemistry of hippocampal proliferation marker Ki-67. Magnification 50 × and 400 ×. Scale bar =20 μm. Data are presented as means ± SEM ( n = 3–4/group). * p < 0.05, ** p < 0.01, ns p > 0.05.

Article Snippet: Anaerobic P. histicola (strain number: DSM19854) from Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ) was cultured in modified PYG medium (the media component is shown in ) at 37°C for 24 h under anaerobic conditions.

Techniques: Immunohistochemistry, Marker

Cohousing with P. histicola -treated mice alleviated the depression-like behaviors in OVX. (A) Central area time of OFT. (B) Transition times of OFT. (C) Total time in open arms of EPM. (D) Transition times in open arms of EPM. (E) Immobility time of TST. (F) Immobility time of FST. (G) H & E staining and its quantifications. Magnification 100 × and 400 ×. Scale bar = 20 μm. (H) Nissl staining and its quantifications. Magnification 100 × and 400 ×. Scale bar = 20 μm. Data are presented as means ± SEM ( n = 4/group). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

Journal: Frontiers in Nutrition

Article Title: Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice

doi: 10.3389/fnut.2021.805465

Figure Lengend Snippet: Cohousing with P. histicola -treated mice alleviated the depression-like behaviors in OVX. (A) Central area time of OFT. (B) Transition times of OFT. (C) Total time in open arms of EPM. (D) Transition times in open arms of EPM. (E) Immobility time of TST. (F) Immobility time of FST. (G) H & E staining and its quantifications. Magnification 100 × and 400 ×. Scale bar = 20 μm. (H) Nissl staining and its quantifications. Magnification 100 × and 400 ×. Scale bar = 20 μm. Data are presented as means ± SEM ( n = 4/group). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

Article Snippet: Anaerobic P. histicola (strain number: DSM19854) from Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ) was cultured in modified PYG medium (the media component is shown in ) at 37°C for 24 h under anaerobic conditions.

Techniques: Staining

A schematic diagram for the mechanism of P. histicola prevention of estrogen deficiency-induced depression via the microbiota–brain axis. P. histicola treatment exerted a neuroprotective effect through downregulating peripheral and central inflammation, the link of microbiota–gut–brain axis, in estrogen deficiency-induced depression model mice. P. histicola, Prevotella histicola ; PAMPs, pathogen-associated molecular pattern; TLR4, toll-like receptors 4; Myd88, myeloid differentiation factor 88; BDNF, brain-derived neurotrophic factor.

Journal: Frontiers in Nutrition

Article Title: Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice

doi: 10.3389/fnut.2021.805465

Figure Lengend Snippet: A schematic diagram for the mechanism of P. histicola prevention of estrogen deficiency-induced depression via the microbiota–brain axis. P. histicola treatment exerted a neuroprotective effect through downregulating peripheral and central inflammation, the link of microbiota–gut–brain axis, in estrogen deficiency-induced depression model mice. P. histicola, Prevotella histicola ; PAMPs, pathogen-associated molecular pattern; TLR4, toll-like receptors 4; Myd88, myeloid differentiation factor 88; BDNF, brain-derived neurotrophic factor.

Article Snippet: Anaerobic P. histicola (strain number: DSM19854) from Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ) was cultured in modified PYG medium (the media component is shown in ) at 37°C for 24 h under anaerobic conditions.

Techniques: Derivative Assay