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MedChemExpress lidocaine solution
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DSMZ blautia producta dsm3507
a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta <t>DSM3507,</t> G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.
Blautia Producta Dsm3507, supplied by DSMZ, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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DSMZ parvimonas micra dsm20468
a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta <t>DSM3507,</t> G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.
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Nihon Kohden corporation multichannel emg amplifier meg-6108
a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta <t>DSM3507,</t> G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.
Multichannel Emg Amplifier Meg 6108, supplied by Nihon Kohden corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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DuPont de Nemours copolyester elastomer hytreltm htr-6108
a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta <t>DSM3507,</t> G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.
Copolyester Elastomer Hytreltm Htr 6108, supplied by DuPont de Nemours, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Nokia Corporation mobile phone nokia 6108
a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta <t>DSM3507,</t> G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.
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Hobbs Medical Inc plastic biliary stent 6108
a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta <t>DSM3507,</t> G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.
Plastic Biliary Stent 6108, supplied by Hobbs Medical Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Evident Corporation 23-gauge injector
a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta <t>DSM3507,</t> G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.
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90
GlobeImmune inc gi-6108
a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta <t>DSM3507,</t> G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.
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Image Search Results


a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta DSM3507, G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.

Journal: Nature microbiology

Article Title: Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria

doi: 10.1038/s41564-019-0596-1

Figure Lengend Snippet: a , Mouse bacterial colonization levels were assessed by qPCR. Genome equivalents not detected or below the limit of quantitation (3×10 2 genome equivalents) are represented as NQ (not quantifiable). Center lines are mean±SEM (n=5 biologically independent samples). Mann-Whitney test for significance: ** p =0.0079, two-tailed. b-h , Lignan levels in mice dosed with b-e , PINO (10 mg/kg) or f-h , PINO-diglucoside (20 mg/kg) measured by Orbitrap mass spectrometry. Panels b,c,f,g represent END levels. Panels d,h represent ENL levels. Panel e represents PINO levels. Values are mean±SEM (n=5 biologically independent samples/colonization group with the following exceptions: b-e , 18-hr urine ( ber + , n= 4 biologically independent samples), colon (GF, n=4 biologically independent samples; ber − , n=3 biologically independent samples), and serum at 6-hr timepoint ( ber + , n= 4 biologically independent samples); g , ileum ( ber + , n= 4 biologically independent samples). Kruskal-Wallis with Dunn’s multiple comparisons test: * p <0.05, ** p <0.01, *** p <0.001. ns: not statistically significant. ber + and ber − : germ-free mice colonized with E. lenta DSM2243 T ( ber + group) or E. lenta 1–3-56 ( ber − group) and B. producta DSM3507, G. pamelaeae 3C, and L. longoviformis DSM17459 T ; mice dosed with PINO-diglucoside were also colonized with C. saccharogumia DSM17460 T . GF: germ-free mice.

Article Snippet: Blautia producta DSM3507 and Lactonifactor longoviformis DSM17459 T were purchased from DSMZ and de novo sequenced as before with draft genomes available ( ).

Techniques: Quantitation Assay, MANN-WHITNEY, Two Tailed Test, Mass Spectrometry