5-fu Search Results


hy-90006  (MedChemExpress)
98
MedChemExpress hy-90006
Hy 90006, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/5-fu/5-Fluorouracil/pmc10985029-40-4-18
Average 98 stars, based on 1 article reviews
hy-90006 - by Bioz Stars, 2026-09
98/100 stars
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fluorouracil 5 fu  (MedChemExpress)
98
MedChemExpress fluorouracil 5 fu
a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, <t>fuchsia:5-Fu,</t> blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a
Fluorouracil 5 Fu, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/5-fu/5-Fluorouracil/pmc09277916-39-0-5
Average 98 stars, based on 1 article reviews
fluorouracil 5 fu - by Bioz Stars, 2026-09
98/100 stars
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5 fluorouracil  (Valiant Co Ltd)
96
Valiant Co Ltd 5 fluorouracil
a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, <t>fuchsia:5-Fu,</t> blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a
5 Fluorouracil, supplied by Valiant Co Ltd, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/5-fu/5-Fluorouracil/bio_rxiv__2025__02__21__639572-58-9-11
Average 96 stars, based on 1 article reviews
5 fluorouracil - by Bioz Stars, 2026-09
96/100 stars
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5 fluorouracil 42a  (Chem Impex International)
95
Chem Impex International 5 fluorouracil 42a
a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, <t>fuchsia:5-Fu,</t> blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a
5 Fluorouracil 42a, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/5-fu/5-Fluorouracil/us08501498-981-18-40
Average 95 stars, based on 1 article reviews
5 fluorouracil 42a - by Bioz Stars, 2026-09
95/100 stars
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3-substituted 5-fu klh  (ImmunoGen Inc)
90
ImmunoGen Inc 3-substituted 5-fu klh
a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, <t>fuchsia:5-Fu,</t> blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a
3 Substituted 5 Fu Klh, supplied by ImmunoGen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/5-fu/3+substituted+5+fu+klh/us07205116-345-32-34
Average 90 stars, based on 1 article reviews
3-substituted 5-fu klh - by Bioz Stars, 2026-09
90/100 stars
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5-fu flurablastin  (Pharmacia Upjohn LLC)
90
Pharmacia Upjohn LLC 5-fu flurablastin
a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, <t>fuchsia:5-Fu,</t> blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a
5 Fu Flurablastin, supplied by Pharmacia Upjohn LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/5-fu/5+fu+flurablastin/us06992207-304-5-13
Average 90 stars, based on 1 article reviews
5-fu flurablastin - by Bioz Stars, 2026-09
90/100 stars
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anticancer drugs 5-fu and l-oxaliplatin  (Changsha huir biological tech Co Ltd)
90
Changsha huir biological tech Co Ltd anticancer drugs 5-fu and l-oxaliplatin
a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, <t>fuchsia:5-Fu,</t> blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a
Anticancer Drugs 5 Fu And L Oxaliplatin, supplied by Changsha huir biological tech Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/5-fu/anticancer+drugs+5+fu+and+l+oxaliplatin/pmc04081406-35-14-15
Average 90 stars, based on 1 article reviews
anticancer drugs 5-fu and l-oxaliplatin - by Bioz Stars, 2026-09
90/100 stars
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5-fu  (FUJIFILM)
90
FUJIFILM 5-fu
a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, <t>fuchsia:5-Fu,</t> blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a
5 Fu, supplied by FUJIFILM, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/5-fu/5+fu/10__1016_slash_j__omtn__2025__102548-95-13-19
Average 90 stars, based on 1 article reviews
5-fu - by Bioz Stars, 2026-09
90/100 stars
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5-fu  (American Pharmaceutical Partners Inc)
90
American Pharmaceutical Partners Inc 5-fu
a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, <t>fuchsia:5-Fu,</t> blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a
5 Fu, supplied by American Pharmaceutical Partners Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/5-fu/5+fu/pm17146438-151-14-15
Average 90 stars, based on 1 article reviews
5-fu - by Bioz Stars, 2026-09
90/100 stars
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5-flourouracil 5-fu  (American Pharmaceutical Partners Inc)
90
American Pharmaceutical Partners Inc 5-flourouracil 5-fu
a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, <t>fuchsia:5-Fu,</t> blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a
5 Flourouracil 5 Fu, supplied by American Pharmaceutical Partners Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/5-fu/5+flourouracil+5+fu/pmc02845897-43-8-10
Average 90 stars, based on 1 article reviews
5-flourouracil 5-fu - by Bioz Stars, 2026-09
90/100 stars
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5-fluorouracil 5-fu  (CSNpharm Inc)
90
CSNpharm Inc 5-fluorouracil 5-fu
a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, <t>fuchsia:5-Fu,</t> blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a
5 Fluorouracil 5 Fu, supplied by CSNpharm Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/5-fu/5+fu/pmc07162922-45-0-2
Average 90 stars, based on 1 article reviews
5-fluorouracil 5-fu - by Bioz Stars, 2026-09
90/100 stars
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5-fluorouracil 5-fu  (Merck KGaA)
90
Merck KGaA 5-fluorouracil 5-fu
a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, <t>fuchsia:5-Fu,</t> blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a
5 Fluorouracil 5 Fu, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/5-fu/5+fluorouracil+5+fu/pm40505838-66-3-6
Average 90 stars, based on 1 article reviews
5-fluorouracil 5-fu - by Bioz Stars, 2026-09
90/100 stars
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Image Search Results


a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, fuchsia:5-Fu, blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a

Journal: BMC Pharmacology & Toxicology

Article Title: A novel nitidine chloride nanoparticle overcomes the stemness of CD133 + EPCAM + Huh7 hepatocellular carcinoma cells for liver cancer therapy

doi: 10.1186/s40360-022-00589-z

Figure Lengend Snippet: a . Representative organ images showing specific tumor targeting of rhodamine B isothiocyanate labeled TPGS-FA/NC nanoparticles 8 h post-injection into mice bearing Huh7 xenograft (T: tumor, Li: liver, H: heart, L: lung, K:kidney, S: spleen, and B:brain; Color scale: radiant efficiency, [p s − 1 cm − 2 sr − 1 ] [μWcm − 2 ] − 1 ). V b . Quantitative analysis of biodistribution in tumors and normal organs, quantified from the organ images. Intravenous treatment of nude mice bearing orthotopic Huh7 xenografts with TPGS-FA/NC nanoparticles (red) and control groups (turquoise: NC, fuchsia:5-Fu, blue: PBS) every other day for a total of five injections (4 mg kg − 1,NC per body weight, indicated by arrows). c . Mice body weight was monitored during the time course of treatments ( n = 5 biologically independent animals, statistics was calculated by two-tailed unpaired t-test presented as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001, p = 4.3 × 10 − 3 ,3.4 × 10 − 3 and 5.0 × 10 − 4 comparing TPGS-FA/NC to NC,5-Fu and PBS, respectively). d . Representative images of liver cancer tumors harvested from mice after treatments * p < 0.05, ** p < 0.01, *** p < 0.001; p = 0.01, 8 × 10 − 4,and 2 × 10 − 4 comparing TPGS-FA/NC to NC, 5-Fu, and PBS, respectively. Source data are provided as a

Article Snippet: 5-fluorouracil (5-Fu) was purchased from MedChemExpress (MCE, Monmouth Junction, NJ, USA).

Techniques: Labeling, Injection, Control, Two Tailed Test