454 Search Results


k03861  (MedChemExpress)
93
MedChemExpress k03861
TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , <t>K03861</t> , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.
K03861, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/454/AUZ+454/pmc09322647-54-33-34
Average 93 stars, based on 1 article reviews
k03861 - by Bioz Stars, 2026-08
93/100 stars
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cd4 t cell isolation kit  (Miltenyi Biotec)
97
Miltenyi Biotec cd4 t cell isolation kit
TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , <t>K03861</t> , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.
Cd4 T Cell Isolation Kit, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/454/CD4%2B+T+Cell+Isolation+Kit%2C+mouse/pm41564590-402-20-26
Average 97 stars, based on 1 article reviews
cd4 t cell isolation kit - by Bioz Stars, 2026-08
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recombinant human noggin protein  (Miltenyi Biotec)
95
Miltenyi Biotec recombinant human noggin protein
TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , <t>K03861</t> , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.
Recombinant Human Noggin Protein, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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recombinant human noggin protein - by Bioz Stars, 2026-08
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atcc 27782 genome  (ATCC)
94
ATCC atcc 27782 genome
TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , <t>K03861</t> , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.
Atcc 27782 Genome, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
atcc 27782 genome - by Bioz Stars, 2026-08
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liquichektm qualitative urine toxicology control  (Bio-Rad)
85
Bio-Rad liquichektm qualitative urine toxicology control
TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , <t>K03861</t> , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.
Liquichektm Qualitative Urine Toxicology Control, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/454/Liquichek+Qualitative+Urine+Toxicology+Control/pm25492522-39-0-11
Average 85 stars, based on 1 article reviews
liquichektm qualitative urine toxicology control - by Bioz Stars, 2026-08
85/100 stars
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anti rabbit secondary antibody conjugated to atto 550  (Rockland Immunochemicals)
93
Rockland Immunochemicals anti rabbit secondary antibody conjugated to atto 550
TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , <t>K03861</t> , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.
Anti Rabbit Secondary Antibody Conjugated To Atto 550, supplied by Rockland Immunochemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
anti rabbit secondary antibody conjugated to atto 550 - by Bioz Stars, 2026-08
93/100 stars
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primary anti cpla2  (Santa Cruz Biotechnology)
96
Santa Cruz Biotechnology primary anti cpla2
TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , <t>K03861</t> , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.
Primary Anti Cpla2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/454/cPLA2+Antibody/10__1194_slash_jlr__m002329-68-7-18
Average 96 stars, based on 1 article reviews
primary anti cpla2 - by Bioz Stars, 2026-08
96/100 stars
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melanoma tumor marker  (Miltenyi Biotec)
93
Miltenyi Biotec melanoma tumor marker
TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , <t>K03861</t> , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.
Melanoma Tumor Marker, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/454/Melanoma+(MCSP)+Antibody%2C+anti-human/bio_rxiv__2022__09__28__509590-209-11-15
Average 93 stars, based on 1 article reviews
melanoma tumor marker - by Bioz Stars, 2026-08
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sirvió de marco de referencia de la disciplina  (ATCC)
93
ATCC sirvió de marco de referencia de la disciplina
TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , <t>K03861</t> , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.
Sirvió De Marco De Referencia De La Disciplina, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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shewanella putrefaciens strain cn32  (ATCC)
90
ATCC shewanella putrefaciens strain cn32
TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , <t>K03861</t> , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.
Shewanella Putrefaciens Strain Cn32, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/454/Escherichia+coli+(Migula)+Castellani+and+Chalmers/pm21846108__es2014049_si_001-24-16-20
Average 90 stars, based on 1 article reviews
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90/100 stars
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mouse igg  (Rockland Immunochemicals)
93
Rockland Immunochemicals mouse igg
TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , <t>K03861</t> , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.
Mouse Igg, supplied by Rockland Immunochemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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dye cytotrack red  (Bio-Rad)
85
Bio-Rad dye cytotrack red
TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , <t>K03861</t> , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.
Dye Cytotrack Red, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , K03861 , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.

Journal: Cancers

Article Title: CDK Inhibition Primes for Anti-PD-L1 Treatment in Triple-Negative Breast Cancer Models

doi: 10.3390/cancers14143361

Figure Lengend Snippet: TNBC cell lines are sensitive to CDK inhibitor SNS-032. ( A ) Three small-molecule CDK inhibitors were tested on TNBC cell lines MDA-MB-231 and MDA-MB-468. Cells were treated with a gradient concentration of CDK inhibitors, and cell viability was tested using MTT assay ( n = 3). Inhibitory effects of palbociclib , K03861 , JNJ-7706621 and SNS-032 [ , ] measured in published cell-free assays are showed in the table, whereas increased inhibition is marked by a higher “+” designation. ( B ) A panel of eight TNBC cell lines were tested against the sensitivity of SNS-032 treatment ( n = 3 for each cell line), compared to CDK4/6 inhibitor palbociclib and IC 50 values were calculated (the Cancer Cell Line Encyclopedia (CCLE) database was used to characterize mRNA expression of CDK2 ). With the exception of BT20, TNBC cells were shown to be more resistant to palbociclib compared to the low half-maximal inhibitory concentration (IC 50 ) for SNS-032 in all cell lines.

Article Snippet: To compare the potency of CDK inhibitors to impair cell viability, breast cancer cell lines were plated on 96-well plates and treated with various concentrations of palbociclib (Merck Life Science Limited, Dorset, UK), K03861 (MedChemexpress LLC., Monmouth Junction, NJ, USA), JNJ-7706621 (Biovision, Oxfordshire, UK) or SNS-032 (Tocris Bioscience, Bristol, UK).

Techniques: Concentration Assay, MTT Assay, Inhibition, Expressing