44835 Search Results


jiangella rhizosphaerae neau yy265t mh144586 jiangella anatolica gtf31t  (ATCC)
90
ATCC jiangella rhizosphaerae neau yy265t mh144586 jiangella anatolica gtf31t
Jiangella Rhizosphaerae Neau Yy265t Mh144586 Jiangella Anatolica Gtf31t, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/jiangella rhizosphaerae neau yy265t mh144586 jiangella anatolica gtf31t/product/ATCC
Average 90 stars, based on 1 article reviews
jiangella rhizosphaerae neau yy265t mh144586 jiangella anatolica gtf31t - by Bioz Stars, 2026-02
90/100 stars
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sirna against mouse cry1  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology sirna against mouse cry1
KL001 inhibited melanogenesis in B16F10 cells. (A) Western blot analysis to detect <t>CRY1</t> protein levels were performed after treatment with KL001 for 48 h. (B) Melanin contents and (C) Fontana-Masson staining photograph are presented after treatment with KL001 in presence or absence of α-MSH for 48 h. Bar = 20 μm. Total length of dendrites per cell was measured on the pictures using ruler. (D, E) B16F10 cells were transfected with <t>siRNA</t> oligonucleotides using transfection reagent. WB analysis was performed after 48 h, and melanin contents were measured after 48 h in the presence of KL001. Data are expressed as the mean ± SD ( n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001 versus non-treated cells. # p < 0.05, ## p < 0.01, ### p < 0.001 versus treated cells with indicated reagents.
Sirna Against Mouse Cry1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sirna against mouse cry1/product/Santa Cruz Biotechnology
Average 93 stars, based on 1 article reviews
sirna against mouse cry1 - by Bioz Stars, 2026-02
93/100 stars
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j gansuensis strain yim 002 t  (DSMZ)
86
DSMZ j gansuensis strain yim 002 t
KL001 inhibited melanogenesis in B16F10 cells. (A) Western blot analysis to detect <t>CRY1</t> protein levels were performed after treatment with KL001 for 48 h. (B) Melanin contents and (C) Fontana-Masson staining photograph are presented after treatment with KL001 in presence or absence of α-MSH for 48 h. Bar = 20 μm. Total length of dendrites per cell was measured on the pictures using ruler. (D, E) B16F10 cells were transfected with <t>siRNA</t> oligonucleotides using transfection reagent. WB analysis was performed after 48 h, and melanin contents were measured after 48 h in the presence of KL001. Data are expressed as the mean ± SD ( n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001 versus non-treated cells. # p < 0.05, ## p < 0.01, ### p < 0.001 versus treated cells with indicated reagents.
J Gansuensis Strain Yim 002 T, supplied by DSMZ, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/j gansuensis strain yim 002 t/product/DSMZ
Average 86 stars, based on 1 article reviews
j gansuensis strain yim 002 t - by Bioz Stars, 2026-02
86/100 stars
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Image Search Results


KL001 inhibited melanogenesis in B16F10 cells. (A) Western blot analysis to detect CRY1 protein levels were performed after treatment with KL001 for 48 h. (B) Melanin contents and (C) Fontana-Masson staining photograph are presented after treatment with KL001 in presence or absence of α-MSH for 48 h. Bar = 20 μm. Total length of dendrites per cell was measured on the pictures using ruler. (D, E) B16F10 cells were transfected with siRNA oligonucleotides using transfection reagent. WB analysis was performed after 48 h, and melanin contents were measured after 48 h in the presence of KL001. Data are expressed as the mean ± SD ( n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001 versus non-treated cells. # p < 0.05, ## p < 0.01, ### p < 0.001 versus treated cells with indicated reagents.

Journal: Frontiers in Pharmacology

Article Title: Cryptochrome 1 activation inhibits melanogenesis and melanosome transport through negative regulation of cAMP/PKA/CREB signaling pathway

doi: 10.3389/fphar.2023.1081030

Figure Lengend Snippet: KL001 inhibited melanogenesis in B16F10 cells. (A) Western blot analysis to detect CRY1 protein levels were performed after treatment with KL001 for 48 h. (B) Melanin contents and (C) Fontana-Masson staining photograph are presented after treatment with KL001 in presence or absence of α-MSH for 48 h. Bar = 20 μm. Total length of dendrites per cell was measured on the pictures using ruler. (D, E) B16F10 cells were transfected with siRNA oligonucleotides using transfection reagent. WB analysis was performed after 48 h, and melanin contents were measured after 48 h in the presence of KL001. Data are expressed as the mean ± SD ( n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001 versus non-treated cells. # p < 0.05, ## p < 0.01, ### p < 0.001 versus treated cells with indicated reagents.

Article Snippet: B16 cells were transfected with siRNA against mouse CRY1 (sc-44835) and CRY2 (sc-44836) from Santa Cruz Biotechnology as the manufacturer’s instructions.

Techniques: Western Blot, Staining, Transfection

KL001 inhibited melanogenesis in human melanocytes. (A) Human melanocytes were treated with KL001 for 48 h and CRY1 expression was measured by western blot analysis. (B) Melanin contents were measured as described in methods. (C) Human melanocytes were stained with Fontana-Masson staining. Bar = 20 μm. Total length of dendrites per cell was measured on the pictures using ruler. (D) Expression of tyrosinase, Myosin Va, Cdc42 and Rab27a were measured using western blotting as described in methods. (E) Phosphorylation level of PKA and CREB were detected. Human melanocytes were pretreated with KL001 for 2 h and stimulated with α-MSH for 20 min in the presence of KL001. Data are expressed as the mean ± SD ( n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001 versus non-treated cells. # p < 0.05, ## p < 0.01, ### p < 0.0001 versus α-MSH -treated cells.

Journal: Frontiers in Pharmacology

Article Title: Cryptochrome 1 activation inhibits melanogenesis and melanosome transport through negative regulation of cAMP/PKA/CREB signaling pathway

doi: 10.3389/fphar.2023.1081030

Figure Lengend Snippet: KL001 inhibited melanogenesis in human melanocytes. (A) Human melanocytes were treated with KL001 for 48 h and CRY1 expression was measured by western blot analysis. (B) Melanin contents were measured as described in methods. (C) Human melanocytes were stained with Fontana-Masson staining. Bar = 20 μm. Total length of dendrites per cell was measured on the pictures using ruler. (D) Expression of tyrosinase, Myosin Va, Cdc42 and Rab27a were measured using western blotting as described in methods. (E) Phosphorylation level of PKA and CREB were detected. Human melanocytes were pretreated with KL001 for 2 h and stimulated with α-MSH for 20 min in the presence of KL001. Data are expressed as the mean ± SD ( n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001 versus non-treated cells. # p < 0.05, ## p < 0.01, ### p < 0.0001 versus α-MSH -treated cells.

Article Snippet: B16 cells were transfected with siRNA against mouse CRY1 (sc-44835) and CRY2 (sc-44836) from Santa Cruz Biotechnology as the manufacturer’s instructions.

Techniques: Expressing, Western Blot, Staining, Phospho-proteomics

A proposed scheme shows that CRY1 activation inhibits melanogenesis and melanosome transport through negative regulation of cAMP/PKA/CREB signaling pathway. cAMP-mediated expression of MITF induces the expression of TYR, Cdc42, and Rab27a, thereby driving melanosome maturation and transport. TYR is a critical enzyme for the melanogenesis and Cdc42 contributes to dendrite extension and filopodia formation. Rab27a interacts with two Rab27a effectors, Mlph and Slp2-a, and thereby regulates actin-dependent melanosome transport and melanosome anchoring to the plasma membrane, respectively.

Journal: Frontiers in Pharmacology

Article Title: Cryptochrome 1 activation inhibits melanogenesis and melanosome transport through negative regulation of cAMP/PKA/CREB signaling pathway

doi: 10.3389/fphar.2023.1081030

Figure Lengend Snippet: A proposed scheme shows that CRY1 activation inhibits melanogenesis and melanosome transport through negative regulation of cAMP/PKA/CREB signaling pathway. cAMP-mediated expression of MITF induces the expression of TYR, Cdc42, and Rab27a, thereby driving melanosome maturation and transport. TYR is a critical enzyme for the melanogenesis and Cdc42 contributes to dendrite extension and filopodia formation. Rab27a interacts with two Rab27a effectors, Mlph and Slp2-a, and thereby regulates actin-dependent melanosome transport and melanosome anchoring to the plasma membrane, respectively.

Article Snippet: B16 cells were transfected with siRNA against mouse CRY1 (sc-44835) and CRY2 (sc-44836) from Santa Cruz Biotechnology as the manufacturer’s instructions.

Techniques: Activation Assay, Expressing, Clinical Proteomics, Membrane