41bbl Search Results


90
Becton Dickinson 41bbl c65–485
(A) Scheme of retroviral constructs. (B) Representative dot plots for CD19-ENG (mOrange), CD80 (PercP) and <t>41BBL</t> (APC) 5 to 7 days post transduction of CD3/CD28-activated T cells with retroviral vectors. (C) Mean and SD of mOrange, CD80, and 41BBL expression (n=3; * p<0.05 compared to CD19-ENG T cells, two-tailed t-test).
41bbl C65–485, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/41bbl c65–485/product/Becton Dickinson
Average 90 stars, based on 1 article reviews
41bbl c65–485 - by Bioz Stars, 2026-04
90/100 stars
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90
Bio X Cell anti-mouse 41bbl
(A) Scheme of retroviral constructs. (B) Representative dot plots for CD19-ENG (mOrange), CD80 (PercP) and <t>41BBL</t> (APC) 5 to 7 days post transduction of CD3/CD28-activated T cells with retroviral vectors. (C) Mean and SD of mOrange, CD80, and 41BBL expression (n=3; * p<0.05 compared to CD19-ENG T cells, two-tailed t-test).
Anti Mouse 41bbl, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti-mouse 41bbl/product/Bio X Cell
Average 90 stars, based on 1 article reviews
anti-mouse 41bbl - by Bioz Stars, 2026-04
90/100 stars
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90
Immunex Corporation anti-41bbl
(A) Scheme of retroviral constructs. (B) Representative dot plots for CD19-ENG (mOrange), CD80 (PercP) and <t>41BBL</t> (APC) 5 to 7 days post transduction of CD3/CD28-activated T cells with retroviral vectors. (C) Mean and SD of mOrange, CD80, and 41BBL expression (n=3; * p<0.05 compared to CD19-ENG T cells, two-tailed t-test).
Anti 41bbl, supplied by Immunex Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti-41bbl/product/Immunex Corporation
Average 90 stars, based on 1 article reviews
anti-41bbl - by Bioz Stars, 2026-04
90/100 stars
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90
Provecs Medical GmbH plasmid pt3_il-12_41bbl_il-2
(A) Scheme of retroviral constructs. (B) Representative dot plots for CD19-ENG (mOrange), CD80 (PercP) and <t>41BBL</t> (APC) 5 to 7 days post transduction of CD3/CD28-activated T cells with retroviral vectors. (C) Mean and SD of mOrange, CD80, and 41BBL expression (n=3; * p<0.05 compared to CD19-ENG T cells, two-tailed t-test).
Plasmid Pt3 Il 12 41bbl Il 2, supplied by Provecs Medical GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/plasmid pt3_il-12_41bbl_il-2/product/Provecs Medical GmbH
Average 90 stars, based on 1 article reviews
plasmid pt3_il-12_41bbl_il-2 - by Bioz Stars, 2026-04
90/100 stars
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90
Cosman Medical 41bbl
(A) Scheme of retroviral constructs. (B) Representative dot plots for CD19-ENG (mOrange), CD80 (PercP) and <t>41BBL</t> (APC) 5 to 7 days post transduction of CD3/CD28-activated T cells with retroviral vectors. (C) Mean and SD of mOrange, CD80, and 41BBL expression (n=3; * p<0.05 compared to CD19-ENG T cells, two-tailed t-test).
41bbl, supplied by Cosman Medical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/41bbl/product/Cosman Medical
Average 90 stars, based on 1 article reviews
41bbl - by Bioz Stars, 2026-04
90/100 stars
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N/A
Rabbit polyclonal 41BBL antibody
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Purified recombinant Human 41BBL protein
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Image Search Results


(A) Scheme of retroviral constructs. (B) Representative dot plots for CD19-ENG (mOrange), CD80 (PercP) and 41BBL (APC) 5 to 7 days post transduction of CD3/CD28-activated T cells with retroviral vectors. (C) Mean and SD of mOrange, CD80, and 41BBL expression (n=3; * p<0.05 compared to CD19-ENG T cells, two-tailed t-test).

Journal: Cancer immunology research

Article Title: CD28 and 41BB costimulation enhance the effector function of CD19-specific engager T cells

doi: 10.1158/2326-6066.CIR-17-0171

Figure Lengend Snippet: (A) Scheme of retroviral constructs. (B) Representative dot plots for CD19-ENG (mOrange), CD80 (PercP) and 41BBL (APC) 5 to 7 days post transduction of CD3/CD28-activated T cells with retroviral vectors. (C) Mean and SD of mOrange, CD80, and 41BBL expression (n=3; * p<0.05 compared to CD19-ENG T cells, two-tailed t-test).

Article Snippet: Flow cytometric analysis Monoclonal antibodies (mAb) for the following markers were used for fluorescence activated cell sorting (FACS) analysis as described elsewhere ( 26 ): 41BBL (Clone C65–485; BD Biosciences, San Jose, CA) conjugated with GAM-APC antibody (BD Biosciences; cat. 550826), CD80-PerCP (eBioscience, San Diego, CA; cat. 46080942); CD3-APC (clone HIT3a; cat. 555342), CD4-PECy7 (clone SK3; cat. 560909), CD8-APCH7 (clone SK1; cat. 560179), CCR7-FITC (clone 150503; cat. 561271), CD62L-APC (clone DREG-56; cat. 559772), CD95-Pacific Blue (clone DX2; cat. 562616), and CD45RO-PercP (clone UCHL1; cat. 560607) (all BD Biosciences, Mountain View, CA).

Techniques: Construct, Transduction, Expressing, Two Tailed Test

(A) Cytotoxicity assays were performed using CD19-ENG, CD19-ENG.CD80, CD19-ENG.41BBL, CD19-ENG.41BBL/CD80 and EphA2-ENG, 41BBL/CD80 T cells as effectors and CD19+ (BV173) and CD19− (KG1a) tumor cells as targets at a E:T ratio of 10:1. Percent lysis is plotted using Tukey box and whisker plots. (n=4; assay performed in triplicates). (B) Effector T cells were cocultured with CD19+ (BV173), CD19− (KG1a) tumor cells, or media only at a ratio of 2:1. After 48 hours, IFNγ and IL2 production was determined by ELISA and plotted using Tukey box and whisker plots (n=5; assay performed in duplicates, significance at p<0.05; one-way ANOVA).

Journal: Cancer immunology research

Article Title: CD28 and 41BB costimulation enhance the effector function of CD19-specific engager T cells

doi: 10.1158/2326-6066.CIR-17-0171

Figure Lengend Snippet: (A) Cytotoxicity assays were performed using CD19-ENG, CD19-ENG.CD80, CD19-ENG.41BBL, CD19-ENG.41BBL/CD80 and EphA2-ENG, 41BBL/CD80 T cells as effectors and CD19+ (BV173) and CD19− (KG1a) tumor cells as targets at a E:T ratio of 10:1. Percent lysis is plotted using Tukey box and whisker plots. (n=4; assay performed in triplicates). (B) Effector T cells were cocultured with CD19+ (BV173), CD19− (KG1a) tumor cells, or media only at a ratio of 2:1. After 48 hours, IFNγ and IL2 production was determined by ELISA and plotted using Tukey box and whisker plots (n=5; assay performed in duplicates, significance at p<0.05; one-way ANOVA).

Article Snippet: Flow cytometric analysis Monoclonal antibodies (mAb) for the following markers were used for fluorescence activated cell sorting (FACS) analysis as described elsewhere ( 26 ): 41BBL (Clone C65–485; BD Biosciences, San Jose, CA) conjugated with GAM-APC antibody (BD Biosciences; cat. 550826), CD80-PerCP (eBioscience, San Diego, CA; cat. 46080942); CD3-APC (clone HIT3a; cat. 555342), CD4-PECy7 (clone SK3; cat. 560909), CD8-APCH7 (clone SK1; cat. 560179), CCR7-FITC (clone 150503; cat. 561271), CD62L-APC (clone DREG-56; cat. 559772), CD95-Pacific Blue (clone DX2; cat. 562616), and CD45RO-PercP (clone UCHL1; cat. 560607) (all BD Biosciences, Mountain View, CA).

Techniques: Lysis, Whisker Assay, Enzyme-linked Immunosorbent Assay

NSG mice were sublethally irradiated and injected i.v. with BV173.ffLuc. On day 7, mice received one i.v. dose of 1×106 CD19-ENG (n=5), CD19-ENG.41BBL/CD80 (n=9), or EphA2-ENG.41BBL/CD80 (n=5) T cells. Tumor growth was monitored by bioluminescence imaging. (A) Images of representative animals. (B) Bioluminescence signal (radiance = photons/sec/cm2/sr) over time is plotted. (C) Shown are weights of animals over the course of the experiment. (D) Kaplan-Meier survival curves for injected mice. Statistical significance was determined using the Wilcoxon rank sum test (p<0.0001).

Journal: Cancer immunology research

Article Title: CD28 and 41BB costimulation enhance the effector function of CD19-specific engager T cells

doi: 10.1158/2326-6066.CIR-17-0171

Figure Lengend Snippet: NSG mice were sublethally irradiated and injected i.v. with BV173.ffLuc. On day 7, mice received one i.v. dose of 1×106 CD19-ENG (n=5), CD19-ENG.41BBL/CD80 (n=9), or EphA2-ENG.41BBL/CD80 (n=5) T cells. Tumor growth was monitored by bioluminescence imaging. (A) Images of representative animals. (B) Bioluminescence signal (radiance = photons/sec/cm2/sr) over time is plotted. (C) Shown are weights of animals over the course of the experiment. (D) Kaplan-Meier survival curves for injected mice. Statistical significance was determined using the Wilcoxon rank sum test (p<0.0001).

Article Snippet: Flow cytometric analysis Monoclonal antibodies (mAb) for the following markers were used for fluorescence activated cell sorting (FACS) analysis as described elsewhere ( 26 ): 41BBL (Clone C65–485; BD Biosciences, San Jose, CA) conjugated with GAM-APC antibody (BD Biosciences; cat. 550826), CD80-PerCP (eBioscience, San Diego, CA; cat. 46080942); CD3-APC (clone HIT3a; cat. 555342), CD4-PECy7 (clone SK3; cat. 560909), CD8-APCH7 (clone SK1; cat. 560179), CCR7-FITC (clone 150503; cat. 561271), CD62L-APC (clone DREG-56; cat. 559772), CD95-Pacific Blue (clone DX2; cat. 562616), and CD45RO-PercP (clone UCHL1; cat. 560607) (all BD Biosciences, Mountain View, CA).

Techniques: Irradiation, Injection, Imaging

NSG mice were sublethally irradiated and injected i.v. with BV173. On day 7, mice received one i.v. dose of 1×106 CD19-ENG.41BBL/CD80 (n=5) or EphA2-ENG.41BBL/CD80 (n=4) T cells that were genetically modified with eGFP.ffLuc. Mice without tumors received one i.v. dose of 1×106 CD19-ENG.41BBL/CD80 (n=5). (A) Images of representative animals over time are shown. (B) Plots of bioluminescence signal (radiance = photons/sec/cm2/sr) of femurs (*p<0.05 for day 1, ***p<0.001 for days 3 and 5, p=ns for day 7, by Gehan-Wilcoxon test).

Journal: Cancer immunology research

Article Title: CD28 and 41BB costimulation enhance the effector function of CD19-specific engager T cells

doi: 10.1158/2326-6066.CIR-17-0171

Figure Lengend Snippet: NSG mice were sublethally irradiated and injected i.v. with BV173. On day 7, mice received one i.v. dose of 1×106 CD19-ENG.41BBL/CD80 (n=5) or EphA2-ENG.41BBL/CD80 (n=4) T cells that were genetically modified with eGFP.ffLuc. Mice without tumors received one i.v. dose of 1×106 CD19-ENG.41BBL/CD80 (n=5). (A) Images of representative animals over time are shown. (B) Plots of bioluminescence signal (radiance = photons/sec/cm2/sr) of femurs (*p<0.05 for day 1, ***p<0.001 for days 3 and 5, p=ns for day 7, by Gehan-Wilcoxon test).

Article Snippet: Flow cytometric analysis Monoclonal antibodies (mAb) for the following markers were used for fluorescence activated cell sorting (FACS) analysis as described elsewhere ( 26 ): 41BBL (Clone C65–485; BD Biosciences, San Jose, CA) conjugated with GAM-APC antibody (BD Biosciences; cat. 550826), CD80-PerCP (eBioscience, San Diego, CA; cat. 46080942); CD3-APC (clone HIT3a; cat. 555342), CD4-PECy7 (clone SK3; cat. 560909), CD8-APCH7 (clone SK1; cat. 560179), CCR7-FITC (clone 150503; cat. 561271), CD62L-APC (clone DREG-56; cat. 559772), CD95-Pacific Blue (clone DX2; cat. 562616), and CD45RO-PercP (clone UCHL1; cat. 560607) (all BD Biosciences, Mountain View, CA).

Techniques: Irradiation, Injection, Genetically Modified