39895 Search Results


92
Santa Cruz Biotechnology cxcr6 sirna
CXCL16, <t>CXCR6,</t> sCXCL16, and circulating Tregs in GIST specimens. Notes: ( A ) Western blot analysis for CXCL16 and CXCR6 expression in specimens. β-actin was used as an internal loading control. ( B ) Representative results of GIST cancer tissues and corresponding noncancerous tissue by immunohistochemical staining. The nuclei were counterstained with hematoxylin. ( C ) sCXCL16 level in serum of the GIST patients was detected by using ELISA. ( D ) Circulating Tregs were determined by using fluorescence-activated cell sorting. ( E ) Positive correlation between sCXCL16 and Tregs in serum of the GIST patients. Abbreviations: GIST, gastrointestinal stromal tumors; ELISA, enzyme-linked immunosorbent assay; N, normal; C, cancer; sCXCL16, serum CXCL16.
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BOC Sciences arsenocholine
CXCL16, <t>CXCR6,</t> sCXCL16, and circulating Tregs in GIST specimens. Notes: ( A ) Western blot analysis for CXCL16 and CXCR6 expression in specimens. β-actin was used as an internal loading control. ( B ) Representative results of GIST cancer tissues and corresponding noncancerous tissue by immunohistochemical staining. The nuclei were counterstained with hematoxylin. ( C ) sCXCL16 level in serum of the GIST patients was detected by using ELISA. ( D ) Circulating Tregs were determined by using fluorescence-activated cell sorting. ( E ) Positive correlation between sCXCL16 and Tregs in serum of the GIST patients. Abbreviations: GIST, gastrointestinal stromal tumors; ELISA, enzyme-linked immunosorbent assay; N, normal; C, cancer; sCXCL16, serum CXCL16.
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Santa Cruz Biotechnology uhrf2
CXCL16, <t>CXCR6,</t> sCXCL16, and circulating Tregs in GIST specimens. Notes: ( A ) Western blot analysis for CXCL16 and CXCR6 expression in specimens. β-actin was used as an internal loading control. ( B ) Representative results of GIST cancer tissues and corresponding noncancerous tissue by immunohistochemical staining. The nuclei were counterstained with hematoxylin. ( C ) sCXCL16 level in serum of the GIST patients was detected by using ELISA. ( D ) Circulating Tregs were determined by using fluorescence-activated cell sorting. ( E ) Positive correlation between sCXCL16 and Tregs in serum of the GIST patients. Abbreviations: GIST, gastrointestinal stromal tumors; ELISA, enzyme-linked immunosorbent assay; N, normal; C, cancer; sCXCL16, serum CXCL16.
Uhrf2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


CXCL16, CXCR6, sCXCL16, and circulating Tregs in GIST specimens. Notes: ( A ) Western blot analysis for CXCL16 and CXCR6 expression in specimens. β-actin was used as an internal loading control. ( B ) Representative results of GIST cancer tissues and corresponding noncancerous tissue by immunohistochemical staining. The nuclei were counterstained with hematoxylin. ( C ) sCXCL16 level in serum of the GIST patients was detected by using ELISA. ( D ) Circulating Tregs were determined by using fluorescence-activated cell sorting. ( E ) Positive correlation between sCXCL16 and Tregs in serum of the GIST patients. Abbreviations: GIST, gastrointestinal stromal tumors; ELISA, enzyme-linked immunosorbent assay; N, normal; C, cancer; sCXCL16, serum CXCL16.

Journal: OncoTargets and therapy

Article Title: The roles of serum CXCL16 in circulating Tregs and gastrointestinal stromal tumor cells

doi: 10.2147/OTT.S105245

Figure Lengend Snippet: CXCL16, CXCR6, sCXCL16, and circulating Tregs in GIST specimens. Notes: ( A ) Western blot analysis for CXCL16 and CXCR6 expression in specimens. β-actin was used as an internal loading control. ( B ) Representative results of GIST cancer tissues and corresponding noncancerous tissue by immunohistochemical staining. The nuclei were counterstained with hematoxylin. ( C ) sCXCL16 level in serum of the GIST patients was detected by using ELISA. ( D ) Circulating Tregs were determined by using fluorescence-activated cell sorting. ( E ) Positive correlation between sCXCL16 and Tregs in serum of the GIST patients. Abbreviations: GIST, gastrointestinal stromal tumors; ELISA, enzyme-linked immunosorbent assay; N, normal; C, cancer; sCXCL16, serum CXCL16.

Article Snippet: CXCR6 siRNA (sc-39895) was obtained from Santa Cruz Biotechnology Inc. (Dallas, TX, USA).

Techniques: Western Blot, Expressing, Control, Immunohistochemical staining, Staining, Enzyme-linked Immunosorbent Assay, Fluorescence, FACS

Relationship between CXCL16 and  CXCR6  expression in situ and clinicopathological parameters of patients with GIST

Journal: OncoTargets and therapy

Article Title: The roles of serum CXCL16 in circulating Tregs and gastrointestinal stromal tumor cells

doi: 10.2147/OTT.S105245

Figure Lengend Snippet: Relationship between CXCL16 and CXCR6 expression in situ and clinicopathological parameters of patients with GIST

Article Snippet: CXCR6 siRNA (sc-39895) was obtained from Santa Cruz Biotechnology Inc. (Dallas, TX, USA).

Techniques: Expressing, In Situ

Kaplan–Meier curves of the cumulative survival rate of patients with GIST. Notes: Based on patients’ CXCL16 ( A ), CXCR6 ( B ), sCXCL16 ( C ) expression or circulating Tregs number ( D ). Abbreviations: GIST, gastrointestinal stromal tumors; sCXCL16, serum CXCL16.

Journal: OncoTargets and therapy

Article Title: The roles of serum CXCL16 in circulating Tregs and gastrointestinal stromal tumor cells

doi: 10.2147/OTT.S105245

Figure Lengend Snippet: Kaplan–Meier curves of the cumulative survival rate of patients with GIST. Notes: Based on patients’ CXCL16 ( A ), CXCR6 ( B ), sCXCL16 ( C ) expression or circulating Tregs number ( D ). Abbreviations: GIST, gastrointestinal stromal tumors; sCXCL16, serum CXCL16.

Article Snippet: CXCR6 siRNA (sc-39895) was obtained from Santa Cruz Biotechnology Inc. (Dallas, TX, USA).

Techniques: Expressing

Recombinant CXCL16 (IC 50 value) displays inhibitory effects on Tregs and GIST cells in vitro. Notes: ( A ) The proliferation ratio was determined by MTT assays. ( B ) Cells were stained with propidium iodide and fluorescence-activated cell sorting analysis was performed. ( C ) Transwell assays were performed to detect migration and invasion of cells. Cells that migrated to the bottom of the membrane were stained and counted. Treg: untreated Tregs; Treg-C: Tregs treated with recombinant CXCL16; Treg-C+S: Tregs treated with recombinant CXCL16 and CXCR6 siRNA; GIST-T1: untreated GIST-T1 cells; GIST-T1-C: GIST-T1 cells treated with recombinant CXCL16; GIST-T1-C+S: GIST-T1 cells treated with recombinant CXCL16 and CXCR6 siRNA; GIST882: untreated GIST882 cells; GIST882-C: GIST882 cells treated with recombinant CXCL16; GIST882-C+S: GIST882 cells treated with recombinant CXCL16 and CXCR6 siRNA. Abbreviations: GIST, gastrointestinal stromal tumors; PI, propidium iodide; IC 50 , half maximal inhibitory concentration; rhCXCL16, recombinant human CXCL16.

Journal: OncoTargets and therapy

Article Title: The roles of serum CXCL16 in circulating Tregs and gastrointestinal stromal tumor cells

doi: 10.2147/OTT.S105245

Figure Lengend Snippet: Recombinant CXCL16 (IC 50 value) displays inhibitory effects on Tregs and GIST cells in vitro. Notes: ( A ) The proliferation ratio was determined by MTT assays. ( B ) Cells were stained with propidium iodide and fluorescence-activated cell sorting analysis was performed. ( C ) Transwell assays were performed to detect migration and invasion of cells. Cells that migrated to the bottom of the membrane were stained and counted. Treg: untreated Tregs; Treg-C: Tregs treated with recombinant CXCL16; Treg-C+S: Tregs treated with recombinant CXCL16 and CXCR6 siRNA; GIST-T1: untreated GIST-T1 cells; GIST-T1-C: GIST-T1 cells treated with recombinant CXCL16; GIST-T1-C+S: GIST-T1 cells treated with recombinant CXCL16 and CXCR6 siRNA; GIST882: untreated GIST882 cells; GIST882-C: GIST882 cells treated with recombinant CXCL16; GIST882-C+S: GIST882 cells treated with recombinant CXCL16 and CXCR6 siRNA. Abbreviations: GIST, gastrointestinal stromal tumors; PI, propidium iodide; IC 50 , half maximal inhibitory concentration; rhCXCL16, recombinant human CXCL16.

Article Snippet: CXCR6 siRNA (sc-39895) was obtained from Santa Cruz Biotechnology Inc. (Dallas, TX, USA).

Techniques: Recombinant, In Vitro, Staining, Fluorescence, FACS, Migration, Membrane, Concentration Assay

Western blot analysis of the ERK/MEK signaling pathway. Notes: Recombinant CXCL16 could induce increased E-cadherin, and decreased p-ERK, p-MEK, MMP2/9, and N-cadherin. However, ERK and MEK showed no changes. β-actin was used as an internal loading control. Treg: untreated Tregs; Treg-C: Tregs treated with recombinant CXCL16; Treg-C+S: Tregs treated with recombinant CXCL16 and CXCR6 siRNA; GIST-T1: untreated GIST-T1 cells; GIST-T1-C: GIST-T1 cells treated with recombinant CXCL16; GIST-T1-C+S: GIST-T1 cells treated with recombinant CXCL16 and CXCR6 siRNA; GIST882: untreated GIST882 cells; GIST882-C: GIST882 cells treated with recombinant CXCL16; GIST882-C+S: GIST882 cells treated with recombinant CXCL16 and CXCR6 siRNA. Abbreviation: GIST, gastrointestinal stromal tumors.

Journal: OncoTargets and therapy

Article Title: The roles of serum CXCL16 in circulating Tregs and gastrointestinal stromal tumor cells

doi: 10.2147/OTT.S105245

Figure Lengend Snippet: Western blot analysis of the ERK/MEK signaling pathway. Notes: Recombinant CXCL16 could induce increased E-cadherin, and decreased p-ERK, p-MEK, MMP2/9, and N-cadherin. However, ERK and MEK showed no changes. β-actin was used as an internal loading control. Treg: untreated Tregs; Treg-C: Tregs treated with recombinant CXCL16; Treg-C+S: Tregs treated with recombinant CXCL16 and CXCR6 siRNA; GIST-T1: untreated GIST-T1 cells; GIST-T1-C: GIST-T1 cells treated with recombinant CXCL16; GIST-T1-C+S: GIST-T1 cells treated with recombinant CXCL16 and CXCR6 siRNA; GIST882: untreated GIST882 cells; GIST882-C: GIST882 cells treated with recombinant CXCL16; GIST882-C+S: GIST882 cells treated with recombinant CXCL16 and CXCR6 siRNA. Abbreviation: GIST, gastrointestinal stromal tumors.

Article Snippet: CXCR6 siRNA (sc-39895) was obtained from Santa Cruz Biotechnology Inc. (Dallas, TX, USA).

Techniques: Western Blot, Recombinant, Control

Multivariate analysis of clinical variables for patients with GIST

Journal: OncoTargets and therapy

Article Title: The roles of serum CXCL16 in circulating Tregs and gastrointestinal stromal tumor cells

doi: 10.2147/OTT.S105245

Figure Lengend Snippet: Multivariate analysis of clinical variables for patients with GIST

Article Snippet: CXCR6 siRNA (sc-39895) was obtained from Santa Cruz Biotechnology Inc. (Dallas, TX, USA).

Techniques: