36641 Search Results


732 seqf2394 01  (ATCC)
92
ATCC 732 seqf2394 01
732 Seqf2394 01, supplied by ATCC, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/732 seqf2394 01/product/ATCC
Average 92 stars, based on 1 article reviews
732 seqf2394 01 - by Bioz Stars, 2026-02
92/100 stars
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tert sirna  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology tert sirna
Tert Sirna, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/tert sirna/product/Santa Cruz Biotechnology
Average 93 stars, based on 1 article reviews
tert sirna - by Bioz Stars, 2026-02
93/100 stars
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tert shrna plasmid  (Santa Cruz Biotechnology)
90
Santa Cruz Biotechnology tert shrna plasmid
Fig. 3. Effects of long-term exposure to MST-312 on cell morphology, telomerase expression and resistance to cytotoxic effects of the compound. (A) Dramatic changes on cell morphology, accessed by polarity index quantification, during the responding phase of long-term treatment. After 200 days of treatment, no difference on this morphological parameter between control and treated group was found (∗∗∗two-tailed p value < 0.001; Mann-Whitney test). (B) The treatment did not change levels of <t>TERT</t> mRNA. (C) Phase contrast micrographs show the resistance of long term MST-312 treated cells to cytotoxic effects of the drug at high concentration, which remains as characteristic of the culture at the end of experiment, showed by trypan blue exclusion assay (D).
Tert Shrna Plasmid, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/tert shrna plasmid/product/Santa Cruz Biotechnology
Average 90 stars, based on 1 article reviews
tert shrna plasmid - by Bioz Stars, 2026-02
90/100 stars
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rnai ready psc-36641-sh-htert-expressing plasmid  (Becton Dickinson)
90
Becton Dickinson rnai ready psc-36641-sh-htert-expressing plasmid
Fig. 3. Effects of long-term exposure to MST-312 on cell morphology, telomerase expression and resistance to cytotoxic effects of the compound. (A) Dramatic changes on cell morphology, accessed by polarity index quantification, during the responding phase of long-term treatment. After 200 days of treatment, no difference on this morphological parameter between control and treated group was found (∗∗∗two-tailed p value < 0.001; Mann-Whitney test). (B) The treatment did not change levels of <t>TERT</t> mRNA. (C) Phase contrast micrographs show the resistance of long term MST-312 treated cells to cytotoxic effects of the drug at high concentration, which remains as characteristic of the culture at the end of experiment, showed by trypan blue exclusion assay (D).
Rnai Ready Psc 36641 Sh Htert Expressing Plasmid, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rnai ready psc-36641-sh-htert-expressing plasmid/product/Becton Dickinson
Average 90 stars, based on 1 article reviews
rnai ready psc-36641-sh-htert-expressing plasmid - by Bioz Stars, 2026-02
90/100 stars
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15-ml vacutainer tube bd 36641  (Becton Dickinson)
90
Becton Dickinson 15-ml vacutainer tube bd 36641
Fig. 3. Effects of long-term exposure to MST-312 on cell morphology, telomerase expression and resistance to cytotoxic effects of the compound. (A) Dramatic changes on cell morphology, accessed by polarity index quantification, during the responding phase of long-term treatment. After 200 days of treatment, no difference on this morphological parameter between control and treated group was found (∗∗∗two-tailed p value < 0.001; Mann-Whitney test). (B) The treatment did not change levels of <t>TERT</t> mRNA. (C) Phase contrast micrographs show the resistance of long term MST-312 treated cells to cytotoxic effects of the drug at high concentration, which remains as characteristic of the culture at the end of experiment, showed by trypan blue exclusion assay (D).
15 Ml Vacutainer Tube Bd 36641, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/15-ml vacutainer tube bd 36641/product/Becton Dickinson
Average 90 stars, based on 1 article reviews
15-ml vacutainer tube bd 36641 - by Bioz Stars, 2026-02
90/100 stars
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Image Search Results


Fig. 3. Effects of long-term exposure to MST-312 on cell morphology, telomerase expression and resistance to cytotoxic effects of the compound. (A) Dramatic changes on cell morphology, accessed by polarity index quantification, during the responding phase of long-term treatment. After 200 days of treatment, no difference on this morphological parameter between control and treated group was found (∗∗∗two-tailed p value < 0.001; Mann-Whitney test). (B) The treatment did not change levels of TERT mRNA. (C) Phase contrast micrographs show the resistance of long term MST-312 treated cells to cytotoxic effects of the drug at high concentration, which remains as characteristic of the culture at the end of experiment, showed by trypan blue exclusion assay (D).

Journal: Tumor Biology

Article Title: Effects of in vitro short- and long-term treatment with telomerase inhibitor in U-251 glioma cells

doi: 10.3233/tub-211515

Figure Lengend Snippet: Fig. 3. Effects of long-term exposure to MST-312 on cell morphology, telomerase expression and resistance to cytotoxic effects of the compound. (A) Dramatic changes on cell morphology, accessed by polarity index quantification, during the responding phase of long-term treatment. After 200 days of treatment, no difference on this morphological parameter between control and treated group was found (∗∗∗two-tailed p value < 0.001; Mann-Whitney test). (B) The treatment did not change levels of TERT mRNA. (C) Phase contrast micrographs show the resistance of long term MST-312 treated cells to cytotoxic effects of the drug at high concentration, which remains as characteristic of the culture at the end of experiment, showed by trypan blue exclusion assay (D).

Article Snippet: U-251 cells were transfected with TERT shRNA plasmid (sc-36641-SH, Santa Cruz Biotechnology®), using the Lipofectamine 3000 protocol, submitted to selection with puromycin for five days and then grown until reach 70% confluence.

Techniques: Expressing, Control, MANN-WHITNEY, Concentration Assay, Trypan Blue Exclusion Assay

Fig. 6. Toxic effect of MST-312 on TERT knock-down U-251 cells. (A) Characterization of knock-down cells by qPCR showing low TERT expression in TERT -shRNA plasmid transfected cells compared to control-shRNA plasmid transfected cells. (B) 72 h dose-response curve (MTT assay, the control is not shown due to the use of log of concentrations - basal viability values in both control and KD groups were comparable) showing that TERT knock-down cells are more resistant to MST-312 effects, which was also clearly demonstrated by phase-contrast microscopy analysis (C). (D) In addition, clonal cultures with high TERT expression exhibited greater susceptibility to high concentration of the drug (50 M) (72 h treatment; ∗two-tailed p value < 0.05; Mann-Whitney test).

Journal: Tumor Biology

Article Title: Effects of in vitro short- and long-term treatment with telomerase inhibitor in U-251 glioma cells

doi: 10.3233/tub-211515

Figure Lengend Snippet: Fig. 6. Toxic effect of MST-312 on TERT knock-down U-251 cells. (A) Characterization of knock-down cells by qPCR showing low TERT expression in TERT -shRNA plasmid transfected cells compared to control-shRNA plasmid transfected cells. (B) 72 h dose-response curve (MTT assay, the control is not shown due to the use of log of concentrations - basal viability values in both control and KD groups were comparable) showing that TERT knock-down cells are more resistant to MST-312 effects, which was also clearly demonstrated by phase-contrast microscopy analysis (C). (D) In addition, clonal cultures with high TERT expression exhibited greater susceptibility to high concentration of the drug (50 M) (72 h treatment; ∗two-tailed p value < 0.05; Mann-Whitney test).

Article Snippet: U-251 cells were transfected with TERT shRNA plasmid (sc-36641-SH, Santa Cruz Biotechnology®), using the Lipofectamine 3000 protocol, submitted to selection with puromycin for five days and then grown until reach 70% confluence.

Techniques: Knockdown, Expressing, shRNA, Plasmid Preparation, Transfection, Control, MTT Assay, Microscopy, Concentration Assay, MANN-WHITNEY