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Image Search Results
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology
Article Title: Investigating the potential mechanism and therapeutic effects of SLXG for cholesterol gallstone treatment.
doi: 10.1016/j.phymed.2024.155886
Figure Lengend Snippet: Fig. 5. Representative 2D diagram and 3D diagram of molecular docking. (a) CYP3A4-quercetin. (b) HMGCR-naringenin. (c) UGT1A1-naringenin. (d) SOAT2- naringenin. (e) The chromatographic peaks corresponding to quercetin and naringenin in the positive ion base peak chromatogram.
Article Snippet:
Techniques:
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology
Article Title: Investigating the potential mechanism and therapeutic effects of SLXG for cholesterol gallstone treatment.
doi: 10.1016/j.phymed.2024.155886
Figure Lengend Snippet: Fig. 6. Validation of the therapeutic effect of active ingredients in treating cholesterol gallstones. (a) A schematic show of the process of animal experiment. (b) The appearance of gallstones of mice in different treatment groups. (c) CGS column chart for mice (n = 6). (d) HE staining, Oil red staining in the liver. (e) Levels of ALT in serum (n = 6). (f) Levels of AST in serum (n = 6). (g-j) Levels of TC (g), TG (h), LDL (i), and HDL (j) in serum (n = 6). (k) The relative content of total bile acids in mouse liver (n = 4). (l) The relative content of TC in mouse liver (n = 6). (m) The relative content of TG in mouse liver (n = 6). (n-p) The relative expression levels of mRNA (n = 6). (q) WB results and statistical analysis bar graphs of HMGCR, UGT1A1, and SOAT2 (n = 6).
Article Snippet:
Techniques: Biomarker Discovery, Staining, Expressing
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology
Article Title: Investigating the potential mechanism and therapeutic effects of SLXG for cholesterol gallstone treatment.
doi: 10.1016/j.phymed.2024.155886
Figure Lengend Snippet: Fig. 7. Surface plasmon resonance. (a) Naringenin -HMGCR interaction anal- ysis based on SPR. (b) Naringenin -SOAT2 interaction analysis based on SPR. (c) Naringenin -UGT1A1 interaction analysis based on SPR.
Article Snippet:
Techniques: SPR Assay
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology
Article Title: Investigating the potential mechanism and therapeutic effects of SLXG for cholesterol gallstone treatment.
doi: 10.1016/j.phymed.2024.155886
Figure Lengend Snippet: Fig. 9. Regulating mouse liver metabolism with SLXG to treat cholesterol gallstones. (a) The relative content of total bile acids in mouse liver (n = 6). (b) The relative content of TC in mouse liver (n = 6). (c) The relative content of TG in mouse liver (n = 6). (d-f) The relative expression levels of mRNA (n = 6). (g) WB results and statistical analysis bar graphs of HMGCR, UGT1A1, and SOAT2 (n = 6).
Article Snippet:
Techniques: Expressing