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ATCC
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Santa Cruz Biotechnology
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Image Search Results
Journal: Molecular psychiatry
Article Title: Neurotoxic effects of postnatal thimerosal are mouse strain dependent.
doi: 10.1038/sj.mp.4001529
Figure Lengend Snippet: Figure 5 KA2 receptor immunoreactivity patterns are abnormal in the hippocampi of thimerosal-treated SJL mice. Coronal sections of hippocampus, 5 wks PN. (a and c) SJL Control, KA2 IHC; (b and d) SJL Thim-vax, KA2 IHC. Regions of CA1 represented in (c and d) are marked (white box) in (a and b). DG, dentate gyrus; sr, stratum radiatum; pcl, pyramidal cell layer. Black bars represent 100 mm; white bars, 50 mm. (a) SJL Control. Note the relative absence of staining in pcl of CA1 subfield. (b) SJL Thim-vax. Reduced KA2 immunostaining is noted in sr of CA1, with increased staining in sr of CA3 and in pcl of CA1 and CA2 relative to SJL Control. (c) SJL Control. Note the parallel orientation of fibers in sr. (d) SJL Thim-vax. Increased staining is seen on CA1 pyramidal neurons relative to that in SJL Control.
Article Snippet: IHC was performed using the primary polyclonal antibodies: rabbit antiN-methyl-D-aspartate (NMDA) receptor (NR) type 1 (NR1, 1 : 25 dilution), rabbit anti-NR2B (1 : 750 dilution, Chemicon);
Techniques: Control, Staining, Immunostaining