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European Directorate for the Quality of Medicines and HealthCare
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Image Search Results
Journal: Journal of the Endocrine Society
Article Title: Subclinically low BMD in young men is associated with compromised bone microarchitecture and lower lean mass
doi: 10.1210/jendso/bvag003
Figure Lengend Snippet: Biomarkers. Fig. 1 depicts all assessed biomarker concentrations. The total hip, femoral neck, or lumbar spine (Lower) group is depicted in black filled circles, while the control (Con) group is in clear squares. A, P1NP (pg/mL); B, alkaline phosphatase (ALP) (pg/mL); C, tartrate-resistant acid phosphatase 5b (TRAP5b) (U/L); D, sclerostin (pmol/L); E, β C-terminal cross-linked telopeptide of type I collagen (βCTX) (pmol/L); F, testosterone (ng/mL); G, estradiol (pg/mL); H, parathyroid hormone (PTH) (pg/mL); I, insulin-like growth factor-1 (IGF-1) (ng/mL); J, insulin-like growth factor-1 binding protein 5 (IGFBP-5) (ng/mL).
Article Snippet: Commercially available enzyme-linked immunosorbent assays were used to determine circulating concentrations of
Techniques: Biomarker Discovery, Control, Binding Assay
Journal: BioResearch Open Access
Article Title: Characterization of Laminins in Healthy Human Aortic Valves and a Modified Decellularized Rat Scaffold
doi: 10.1089/biores.2020.0018
Figure Lengend Snippet: Laminin chain expression in human aortic valves. The endothelial basement membrane covering the valve cusps were positive for laminin α4, α5, β1, β2, and γ1, as well as the endothelial lining of interstitial vessels and minor patches in the interstitium. Images of α1, α2, α3, β3, and γ2 show absence of immunoreactivity. A representative image of ≥3 tissue sections from each of the three donor valve cusps is shown. All images shown at 20 × magnification. Scale bar represents 100 μm.
Article Snippet: Antibodies against collagen I (Ab34710), elastin (clone BA-4; Abcam),
Techniques: Expressing, Membrane
Journal: BioResearch Open Access
Article Title: Characterization of Laminins in Healthy Human Aortic Valves and a Modified Decellularized Rat Scaffold
doi: 10.1089/biores.2020.0018
Figure Lengend Snippet: Expression of laminin α4, α5, and γ1 in rat aortic valves. The endothelial basement membrane stained positive for all three laminin chains. Minimal immunoreactivity was seen in the interstitium. A representative image of ≥4 tissue sections from three animals per group is shown. All images captured with 20 × magnification. Scale bar represents 100 μm.
Article Snippet: Antibodies against collagen I (Ab34710), elastin (clone BA-4; Abcam),
Techniques: Expressing, Membrane, Staining
Journal: BioResearch Open Access
Article Title: Characterization of Laminins in Healthy Human Aortic Valves and a Modified Decellularized Rat Scaffold
doi: 10.1089/biores.2020.0018
Figure Lengend Snippet: Histology of normal and decellularized rat aortic valves. H&E images and DAPI staining of cell nuclei reveal absence of intact nuclei after decellularization. Laminin γ1, collagen IV, perlecan, heparan sulfate, and fibronectin was visualized in both normal controls and decellularized valves, with a largely preserved distribution pattern after decellularization. A representative image of ≥3 tissue sections from three animals per group is shown. All images were captured at 20 × magnification. Scale bar represents 100 μm. LNγ1, laminin γ1; COL IV, collagen IV; PLN, perlecan; HS, heparan sulfate; FN, fibronectin.
Article Snippet: Antibodies against collagen I (Ab34710), elastin (clone BA-4; Abcam),
Techniques: Staining