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Image Search Results
Journal: Clinical & Translational Immunology
Article Title: Antibody glycosylation correlates with disease progression in SIV‐ Mycobacterium tuberculosis coinfected cynomolgus macaques
doi: 10.1002/cti2.1474
Figure Lengend Snippet: Simian immunodeficiency virus (SIV) infection impairs humoral immunity. Change from baseline (prior to any infection) in plasma humoral profiles (IgG, IgG1, IgG2, IgG3, FcγRIIa and FcγRIIIa) 8 weeks following infection with Mycobacterium tuberculosis ( Mtb ) in MCM without SIV (naïve; n = 8; yellow left bar) or coinfected with SIV (coinfection; n = 7; red right bar) as determined by multiplexing to Mtb soluble cell wall, cell wall fraction, cell membrane, cytosol fraction, TX114 proteins, peptidoglycan and cell lysate. Change in median fluorescence intensity data was normalised via z ‐scoring before being represented as a heatmap (red indicates higher levels and blue indicates lower levels). Multiplex assays were repeated in duplicate.
Article Snippet: Mtb antigens of the H37Rv strain (sourced from
Techniques: Virus, Infection, Clinical Proteomics, Multiplexing, Membrane, Fluorescence, Multiplex Assay