14693 Search Results


90
ATCC gu214693 ramularia pratensis var
Gu214693 Ramularia Pratensis Var, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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92
Addgene inc robert lefkowitz
Robert Lefkowitz, supplied by Addgene inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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94
Cell Signaling Technology Inc ptpn22 rabbit mab
Fig. 8 | Disruption of the ARE motif in the 5’UTR of <t>Ptpn22</t> modulates its expression in male T cells. male T cell activity and T cell functional popula- tions. a RT-PCR quantification of Ptpn22 transcript levels in DN (left) and CD8SP (right) thymocytes from 8-week-old NOD males that were either sham-operated (filled circles) or castrated (open circles) as 4-week-olds. Mean ± sem. Significance was cal- culated using an unpaired t-test. Symbols - individual mice. n = 4/group. b RT-PCR quantification of Ptpn22 in DN (left) and CD8SP (right) thymocytes from 8 to 9-week- old NOD AR wild-type (filles circles) and knock-out (open circles) males. Delta CT inversely correlates with the strength of expression. Symbols – individual mice. Combined data from two experiments. Number of mice: AR wild-type n = 12/group, AR KO n = 7/group. Mean ± sem. Significance was calculated using an unpaired t-test. The significance of interaction between sex and Ptpn22 mutation was calculated using
Ptpn22 Rabbit Mab, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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93
Proteintech anti slc25a39
Fig. 8 | Disruption of the ARE motif in the 5’UTR of <t>Ptpn22</t> modulates its expression in male T cells. male T cell activity and T cell functional popula- tions. a RT-PCR quantification of Ptpn22 transcript levels in DN (left) and CD8SP (right) thymocytes from 8-week-old NOD males that were either sham-operated (filled circles) or castrated (open circles) as 4-week-olds. Mean ± sem. Significance was cal- culated using an unpaired t-test. Symbols - individual mice. n = 4/group. b RT-PCR quantification of Ptpn22 in DN (left) and CD8SP (right) thymocytes from 8 to 9-week- old NOD AR wild-type (filles circles) and knock-out (open circles) males. Delta CT inversely correlates with the strength of expression. Symbols – individual mice. Combined data from two experiments. Number of mice: AR wild-type n = 12/group, AR KO n = 7/group. Mean ± sem. Significance was calculated using an unpaired t-test. The significance of interaction between sex and Ptpn22 mutation was calculated using
Anti Slc25a39, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Merck KGaA photocheck solutions photocheck 14693
Fig. 8 | Disruption of the ARE motif in the 5’UTR of <t>Ptpn22</t> modulates its expression in male T cells. male T cell activity and T cell functional popula- tions. a RT-PCR quantification of Ptpn22 transcript levels in DN (left) and CD8SP (right) thymocytes from 8-week-old NOD males that were either sham-operated (filled circles) or castrated (open circles) as 4-week-olds. Mean ± sem. Significance was cal- culated using an unpaired t-test. Symbols - individual mice. n = 4/group. b RT-PCR quantification of Ptpn22 in DN (left) and CD8SP (right) thymocytes from 8 to 9-week- old NOD AR wild-type (filles circles) and knock-out (open circles) males. Delta CT inversely correlates with the strength of expression. Symbols – individual mice. Combined data from two experiments. Number of mice: AR wild-type n = 12/group, AR KO n = 7/group. Mean ± sem. Significance was calculated using an unpaired t-test. The significance of interaction between sex and Ptpn22 mutation was calculated using
Photocheck Solutions Photocheck 14693, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Fig. 8 | Disruption of the ARE motif in the 5’UTR of Ptpn22 modulates its expression in male T cells. male T cell activity and T cell functional popula- tions. a RT-PCR quantification of Ptpn22 transcript levels in DN (left) and CD8SP (right) thymocytes from 8-week-old NOD males that were either sham-operated (filled circles) or castrated (open circles) as 4-week-olds. Mean ± sem. Significance was cal- culated using an unpaired t-test. Symbols - individual mice. n = 4/group. b RT-PCR quantification of Ptpn22 in DN (left) and CD8SP (right) thymocytes from 8 to 9-week- old NOD AR wild-type (filles circles) and knock-out (open circles) males. Delta CT inversely correlates with the strength of expression. Symbols – individual mice. Combined data from two experiments. Number of mice: AR wild-type n = 12/group, AR KO n = 7/group. Mean ± sem. Significance was calculated using an unpaired t-test. The significance of interaction between sex and Ptpn22 mutation was calculated using

Journal: Nature communications

Article Title: Androgens contribute to sex bias of autoimmunity in mice by T cell-intrinsic regulation of Ptpn22 phosphatase expression.

doi: 10.1038/s41467-024-51869-7

Figure Lengend Snippet: Fig. 8 | Disruption of the ARE motif in the 5’UTR of Ptpn22 modulates its expression in male T cells. male T cell activity and T cell functional popula- tions. a RT-PCR quantification of Ptpn22 transcript levels in DN (left) and CD8SP (right) thymocytes from 8-week-old NOD males that were either sham-operated (filled circles) or castrated (open circles) as 4-week-olds. Mean ± sem. Significance was cal- culated using an unpaired t-test. Symbols - individual mice. n = 4/group. b RT-PCR quantification of Ptpn22 in DN (left) and CD8SP (right) thymocytes from 8 to 9-week- old NOD AR wild-type (filles circles) and knock-out (open circles) males. Delta CT inversely correlates with the strength of expression. Symbols – individual mice. Combined data from two experiments. Number of mice: AR wild-type n = 12/group, AR KO n = 7/group. Mean ± sem. Significance was calculated using an unpaired t-test. The significance of interaction between sex and Ptpn22 mutation was calculated using

Article Snippet: Following list of primary antibodies was used: PTPN22 Rabbit mAb (1:1000, cat#14693S, Lot# 1, Cell signaling technology, Danvers, MA), ARRabbitmAb (1:2000, cat# 5153T, Lot# 7, Abcam,Cambridge, United Kingdom), and TCF1 Rat mAb (1:500, Biolegend, cat#615701).

Techniques: Disruption, Expressing, Activity Assay, Functional Assay, Reverse Transcription Polymerase Chain Reaction, Knock-Out, Mutagenesis