12799 Search Results


acetyl histone h2b  (Cell Signaling Technology Inc)
94
Cell Signaling Technology Inc acetyl histone h2b
FIGURE 5 Hydroxamic acid derivatives 7d and 7p induce inhibition of histone deacetylase (HDAC) class I and II enzyme activity in THP‐1 cells. (a) The inhibitory effects of vorinostat 1, 7d, and 7p on the enzyme activity of HDAC class I and II were determined using the HDAC‐Glo™ I/II Assay. The results are expressed as the mean ± SD of three independent experiments. The levels of histone H2A, <t>H2B,</t> H3, or H4 acetylation after (b) 24 h or (c) 48 h of treatment with vorinostat 1, 7d, and 7p were determined by immunoblot analysis using appropriate antibodies. Representative immunoblots of one of three experiments are shown. CTRL is a drug‐free control.
Acetyl Histone H2b, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/12799/Acetyl-Histone+H2B+(Lys5)+XP+Rabbit+mAb/pm40165669-377-38-56
Average 94 stars, based on 1 article reviews
acetyl histone h2b - by Bioz Stars, 2026-08
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soybean cultivar s110141  (ATCC)
90
ATCC soybean cultivar s110141
FIGURE 5 Hydroxamic acid derivatives 7d and 7p induce inhibition of histone deacetylase (HDAC) class I and II enzyme activity in THP‐1 cells. (a) The inhibitory effects of vorinostat 1, 7d, and 7p on the enzyme activity of HDAC class I and II were determined using the HDAC‐Glo™ I/II Assay. The results are expressed as the mean ± SD of three independent experiments. The levels of histone H2A, <t>H2B,</t> H3, or H4 acetylation after (b) 24 h or (c) 48 h of treatment with vorinostat 1, 7d, and 7p were determined by immunoblot analysis using appropriate antibodies. Representative immunoblots of one of three experiments are shown. CTRL is a drug‐free control.
Soybean Cultivar S110141, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/12799/Soybean+Cultivar+S110141/us08426699-981-13-18
Average 90 stars, based on 1 article reviews
soybean cultivar s110141 - by Bioz Stars, 2026-08
90/100 stars
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non ehec  (ATCC)
90
ATCC non ehec
FIGURE 5 Hydroxamic acid derivatives 7d and 7p induce inhibition of histone deacetylase (HDAC) class I and II enzyme activity in THP‐1 cells. (a) The inhibitory effects of vorinostat 1, 7d, and 7p on the enzyme activity of HDAC class I and II were determined using the HDAC‐Glo™ I/II Assay. The results are expressed as the mean ± SD of three independent experiments. The levels of histone H2A, <t>H2B,</t> H3, or H4 acetylation after (b) 24 h or (c) 48 h of treatment with vorinostat 1, 7d, and 7p were determined by immunoblot analysis using appropriate antibodies. Representative immunoblots of one of three experiments are shown. CTRL is a drug‐free control.
Non Ehec, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/12799/Escherichia+coli+serotype+o86a%2C+86b%3Ak64/pmc04222638-191-15-20
Average 90 stars, based on 1 article reviews
non ehec - by Bioz Stars, 2026-08
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deposit no 202226  (ATCC)
93
ATCC deposit no 202226
FIGURE 5 Hydroxamic acid derivatives 7d and 7p induce inhibition of histone deacetylase (HDAC) class I and II enzyme activity in THP‐1 cells. (a) The inhibitory effects of vorinostat 1, 7d, and 7p on the enzyme activity of HDAC class I and II were determined using the HDAC‐Glo™ I/II Assay. The results are expressed as the mean ± SD of three independent experiments. The levels of histone H2A, <t>H2B,</t> H3, or H4 acetylation after (b) 24 h or (c) 48 h of treatment with vorinostat 1, 7d, and 7p were determined by immunoblot analysis using appropriate antibodies. Representative immunoblots of one of three experiments are shown. CTRL is a drug‐free control.
Deposit No 202226, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/12799/Escherichia+coli+(Migula)+Castellani+and+Chalmers/us07018629-97-16-15
Average 93 stars, based on 1 article reviews
deposit no 202226 - by Bioz Stars, 2026-08
93/100 stars
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triethylsiliane tes  (Chem Impex International)
95
Chem Impex International triethylsiliane tes
FIGURE 5 Hydroxamic acid derivatives 7d and 7p induce inhibition of histone deacetylase (HDAC) class I and II enzyme activity in THP‐1 cells. (a) The inhibitory effects of vorinostat 1, 7d, and 7p on the enzyme activity of HDAC class I and II were determined using the HDAC‐Glo™ I/II Assay. The results are expressed as the mean ± SD of three independent experiments. The levels of histone H2A, <t>H2B,</t> H3, or H4 acetylation after (b) 24 h or (c) 48 h of treatment with vorinostat 1, 7d, and 7p were determined by immunoblot analysis using appropriate antibodies. Representative immunoblots of one of three experiments are shown. CTRL is a drug‐free control.
Triethylsiliane Tes, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/12799/TES/pm32065973-69-9-20
Average 95 stars, based on 1 article reviews
triethylsiliane tes - by Bioz Stars, 2026-08
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dct.vv.orf111 (plasmid #12799)  (Addgene inc)
N/A
Standard format: Plasmid sent in bacteria as agar stab
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Image Search Results


FIGURE 5 Hydroxamic acid derivatives 7d and 7p induce inhibition of histone deacetylase (HDAC) class I and II enzyme activity in THP‐1 cells. (a) The inhibitory effects of vorinostat 1, 7d, and 7p on the enzyme activity of HDAC class I and II were determined using the HDAC‐Glo™ I/II Assay. The results are expressed as the mean ± SD of three independent experiments. The levels of histone H2A, H2B, H3, or H4 acetylation after (b) 24 h or (c) 48 h of treatment with vorinostat 1, 7d, and 7p were determined by immunoblot analysis using appropriate antibodies. Representative immunoblots of one of three experiments are shown. CTRL is a drug‐free control.

Journal: Archiv der Pharmazie

Article Title: New potent N-hydroxycinnamamide-based histone deacetylase inhibitors suppress proliferation and trigger apoptosis in THP-1 leukaemia cells.

doi: 10.1002/ardp.202400889

Figure Lengend Snippet: FIGURE 5 Hydroxamic acid derivatives 7d and 7p induce inhibition of histone deacetylase (HDAC) class I and II enzyme activity in THP‐1 cells. (a) The inhibitory effects of vorinostat 1, 7d, and 7p on the enzyme activity of HDAC class I and II were determined using the HDAC‐Glo™ I/II Assay. The results are expressed as the mean ± SD of three independent experiments. The levels of histone H2A, H2B, H3, or H4 acetylation after (b) 24 h or (c) 48 h of treatment with vorinostat 1, 7d, and 7p were determined by immunoblot analysis using appropriate antibodies. Representative immunoblots of one of three experiments are shown. CTRL is a drug‐free control.

Article Snippet: [82,86] Membranes were stained overnight at 4°C with appropriate primary antibodies: anti‐β‐actin antibody (Santa Cruz Biotechnology), antibodies against cyclin E1 (Clone: HE12, Cat. #: sc‐ 247), p‐Rb [Ser 807/811] (sc‐16670‐R), cleaved PARP (D64E10, 5625), acetyl‐histone H2A [Lys5] (2576), acetyl‐histone H2B [Lys5] (D5H1S, 12799), acetyl‐histone H3 [Lys9] (C5B11, 9649) and acetyl‐ histone H4 [Lys8] (2594) were purchased Cell Signalling Technology.

Techniques: Inhibition, Histone Deacetylase Assay, Activity Assay, Ii Assay, Western Blot, Control