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A patient-derived next-generation organoid cancer model generated by the Human Cancer Models Initiative (HCMI). HCM-SANG-0286-C20 (ATCC No. PDM-62) was isolated from primary rectal adenocarcinoma tissue. This tumor-derived model can be used in basic research and
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Image Search Results
Journal: eLife
Article Title: Synergism of type 1 metabotropic and ionotropic glutamate receptors in cerebellar molecular layer interneurons in vivo
doi: 10.7554/elife.56839
Figure Lengend Snippet: Figure 4. Synergy between iGluRs and mGluR1s in adult MLIs. (A) A mixture of 300 mM GYKI53655 and 100 mM DCK blocked somatic Cai rises under various PF stimulation protocols in vivo. (B) Ratios between peak amplitudes of DF/Fo in the blockers over control (n = 6 in each condition). (C,D) GCaMP3 imaging of PF-induced Cai rises in 2 somata and 4 putative neurites in vivo shows no difference between control (black traces) and addition of 40 mM IEM 1460 (yellow traces).
Article Snippet: Glutamate receptor antagonists GYKI 53655, 5,7-Dichlorokynurenic
Techniques: In Vivo, Control, Imaging
Journal: Stem cell research
Article Title: Antisense oligonucleotide therapy rescues aggresome formation in a novel Spinocerebellar Ataxia type 3 human embryonic stem cell line.
doi: 10.1016/j.scr.2019.101504
Figure Lengend Snippet: KEY RESOURCES TABLE
Article Snippet:
Techniques: Software