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Image Search Results
Journal: Aging (Albany NY)
Article Title: TLR3 deletion inhibits programmed necrosis of brain cells in neonatal mice with sevoflurane-induced cognitive dysfunction
doi: 10.18632/aging.204092
Figure Lengend Snippet: TLR3 deletion inhibited activation of TRIF and degradation of SHP2 and down-regulated expressions of TLR signaling pathway-related proteins. ( A ) Expressions of TLR3, p-TRIF and SHP2 in the hippocampus of neonatal mice. ( B ) Expressions of p-RIP3 and CaMKII in the hippocampus of neonatal mice. ( C ) Expressions of NLRP3, GSDMD, Caspase-1, Caspase-4 and Caspase-11 in the hippocampus of neonatal mice. ** p < 0.01, and * p < 0.05.
Article Snippet: The hippocampal neurons were extracted from WT,
Techniques: Activation Assay
Journal: Aging (Albany NY)
Article Title: TLR3 deletion inhibits programmed necrosis of brain cells in neonatal mice with sevoflurane-induced cognitive dysfunction
doi: 10.18632/aging.204092
Figure Lengend Snippet: TLR3 deletion inhibited RIP3 phosphorylation and reduced programmed necrosis of hippocampal neurons by regulating TRIF and SHP2 expressions. ( A ) Expressions of TLR3, p-TRIF, SHP2, p-RIP3 and CaMKII in the hippocampal neurons. ( B ) Expressions of NLRP3, GSDMD, Caspase-1, Caspase-4 and Caspase-11 in the hippocampal neurons. ** p < 0.01.
Article Snippet: The hippocampal neurons were extracted from WT,
Techniques: Phospho-proteomics