Journal: Antibiotics

Article Title: Alkyl Pyridinol Compounds Exhibit Antimicrobial Effects against Gram-Positive Bacteria

doi: 10.3390/antibiotics13090897

Figure Lengend Snippet: Minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) of the indicated compounds tested against Gram-negative P. aeruginosa and Gram-positive S. aureus /MRSA strains. MIC and MBC values were determined as described in the Material and Methods. ND, not determined.

Article Snippet: To assess the impact of the nitrogen position in our newly synthesized anaephene derivates, we analyzed their antimicrobial activities against various S. aureus strains, including ATCC 25,923 and the two methicillin-resistant S. aureus (MRSA) strains ATCC 33,591 and ATCC BAA-44.

Techniques:

Journal: Antibiotics

Article Title: Alkyl Pyridinol Compounds Exhibit Antimicrobial Effects against Gram-Positive Bacteria

doi: 10.3390/antibiotics13090897

Figure Lengend Snippet: FIC index of JC-01-074, tested in combination with ampicillin, gentamicin, ciprofloxacin, doxycycline, vancomycin, and chloramphenicol. FICs were calculated as the ratio of the MIC of the antimicrobial in combination with the MIC of the antimicrobial alone. Interactions were categorized as synergistic (<0.5), additive or no interaction (0.5–2), and antagonistic (>2). FICs were calculated from three biological replicates.

Article Snippet: To assess the impact of the nitrogen position in our newly synthesized anaephene derivates, we analyzed their antimicrobial activities against various S. aureus strains, including ATCC 25,923 and the two methicillin-resistant S. aureus (MRSA) strains ATCC 33,591 and ATCC BAA-44.

Techniques: