ro3244794 r 3 4 fluoro phenyl 2 5 4 fluoro phenyl benzofuran 2 ylmethoxycarbonylamino propionic acid  (Millipore)

 
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    Structured Review

    Millipore ro3244794 r 3 4 fluoro phenyl 2 5 4 fluoro phenyl benzofuran 2 ylmethoxycarbonylamino propionic acid
    Structures of (a) RO1138452 ((4,5-dihydro-1H-imidazol-2-yl)-[4-(4-isopropoxy-benzyl)-phenyl]-amine), and (b) RO3244794 ( R <t>-3-(4-fluoro-phenyl)-2-[5-(4-fluoro-phenyl)-benzofuran-2-ylmethoxycarbonylamino]-propionic</t> acid).
    Ro3244794 R 3 4 Fluoro Phenyl 2 5 4 Fluoro Phenyl Benzofuran 2 Ylmethoxycarbonylamino Propionic Acid, supplied by Millipore, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ro3244794 r 3 4 fluoro phenyl 2 5 4 fluoro phenyl benzofuran 2 ylmethoxycarbonylamino propionic acid/product/Millipore
    Average 97 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    ro3244794 r 3 4 fluoro phenyl 2 5 4 fluoro phenyl benzofuran 2 ylmethoxycarbonylamino propionic acid - by Bioz Stars, 2022-11
    97/100 stars

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    1) Product Images from "RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists"

    Article Title: RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists

    Journal:

    doi: 10.1038/sj.bjp.0706554

    Structures of (a) RO1138452 ((4,5-dihydro-1H-imidazol-2-yl)-[4-(4-isopropoxy-benzyl)-phenyl]-amine), and (b) RO3244794 ( R -3-(4-fluoro-phenyl)-2-[5-(4-fluoro-phenyl)-benzofuran-2-ylmethoxycarbonylamino]-propionic acid).
    Figure Legend Snippet: Structures of (a) RO1138452 ((4,5-dihydro-1H-imidazol-2-yl)-[4-(4-isopropoxy-benzyl)-phenyl]-amine), and (b) RO3244794 ( R -3-(4-fluoro-phenyl)-2-[5-(4-fluoro-phenyl)-benzofuran-2-ylmethoxycarbonylamino]-propionic acid).

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    Millipore ro3244794 r 3 4 fluoro phenyl 2 5 4 fluoro phenyl benzofuran 2 ylmethoxycarbonylamino propionic acid
    Structures of (a) RO1138452 ((4,5-dihydro-1H-imidazol-2-yl)-[4-(4-isopropoxy-benzyl)-phenyl]-amine), and (b) RO3244794 ( R <t>-3-(4-fluoro-phenyl)-2-[5-(4-fluoro-phenyl)-benzofuran-2-ylmethoxycarbonylamino]-propionic</t> acid).
    Ro3244794 R 3 4 Fluoro Phenyl 2 5 4 Fluoro Phenyl Benzofuran 2 Ylmethoxycarbonylamino Propionic Acid, supplied by Millipore, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ro3244794 r 3 4 fluoro phenyl 2 5 4 fluoro phenyl benzofuran 2 ylmethoxycarbonylamino propionic acid/product/Millipore
    Average 97 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    ro3244794 r 3 4 fluoro phenyl 2 5 4 fluoro phenyl benzofuran 2 ylmethoxycarbonylamino propionic acid - by Bioz Stars, 2022-11
    97/100 stars
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    Structures of (a) RO1138452 ((4,5-dihydro-1H-imidazol-2-yl)-[4-(4-isopropoxy-benzyl)-phenyl]-amine), and (b) RO3244794 ( R -3-(4-fluoro-phenyl)-2-[5-(4-fluoro-phenyl)-benzofuran-2-ylmethoxycarbonylamino]-propionic acid).

    Journal:

    Article Title: RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists

    doi: 10.1038/sj.bjp.0706554

    Figure Lengend Snippet: Structures of (a) RO1138452 ((4,5-dihydro-1H-imidazol-2-yl)-[4-(4-isopropoxy-benzyl)-phenyl]-amine), and (b) RO3244794 ( R -3-(4-fluoro-phenyl)-2-[5-(4-fluoro-phenyl)-benzofuran-2-ylmethoxycarbonylamino]-propionic acid).

    Article Snippet: The HCl salts of RO1138452 ((4,5-dihydro-1H-imidazol-2-yl)-[4-(4-isopropoxy-benzyl)-phenyl]-amine), RO3244794 ( R -3-(4-fluoro-phenyl)-2-[5-(4-fluoro-phenyl)-benzofuran-2-ylmethoxycarbonylamino]-propionic acid) and the sodium salt of indomethacin (Sigma-Aldrich Corp. (St Louis, MO, U.S.A.)) were synthesized by the Roche Palo Alto Department of Medicinal Chemistry using methods described in previous publications or patents from our laboratory ( ; ).

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