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dr5 analyte  (R&D Systems)


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    Structured Review

    R&D Systems dr5 analyte
    a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to <t>DR5</t> (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.
    Dr5 Analyte, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dr5 analyte/product/R&D Systems
    Average 93 stars, based on 1 article reviews
    dr5 analyte - by Bioz Stars, 2025-04
    93/100 stars

    Images

    1) Product Images from "A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns"

    Article Title: A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns

    Journal: Nature Nanotechnology

    doi: 10.1038/s41565-024-01676-4

    a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to DR5 (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.
    Figure Legend Snippet: a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to DR5 (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.

    Techniques Used: Flow Cytometry



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    a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to <t>DR5</t> (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.
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    a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to <t>DR5</t> (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.
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    a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to <t>DR5</t> (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.
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    a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to <t>DR5</t> (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.
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    Image Search Results


    a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to DR5 (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.

    Journal: Nature Nanotechnology

    Article Title: A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns

    doi: 10.1038/s41565-024-01676-4

    Figure Lengend Snippet: a , Experimental setup of cancer cell treatment with Cy5-labelled origami at pH 7.4 or 6.5. b , The Cy5 signal of SK-BR-3 cells treated with 5 nM empty origami, PEG_pH_O 6p at pH 7.4 or 6.5, measured by flow cytometry. c , Localization of Cy5-labelled origamis (magenta) relative to DR5 (cyan; detected using Alexa488-labelled anti-DR5 monoclonal antibody) on SK-BR-3 cells. The co-localization of the magenta and cyan is shown in grey. Maximum intensity projections from z -stacks. Scale bars, 20 μm.

    Article Snippet: The DR5 analyte (R&D Systems, 10140-T2) was diluted from 516 nM to 32.25 nM and injected as a single-cycle kinetics experiment, with a flow rate of 30 µl min −1 , and 500 s contact time for each concentration.

    Techniques: Flow Cytometry