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rat monoclonal antibody to hcn4  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology rat monoclonal antibody to hcn4
    Figure 2. HCN1 is a major component of If in the sinoatrial node (SAN). A, HCN channel expression in SAN and atrial tissue (AT). HCN1 protein is present in wild-type (WT) and absent in HCN1−/− SAN (top). The same Western blot was reprobed for <t>HCN4</t> and HCN2 (middle). Tubulin served as loading control (bottom). B, Whole-mount SAN preparation of a WT mouse depicting the central SAN area, crista terminalis (CT), superior vena cava (SVC), right atrium (RA), and septum (SEP). Scale bar, 500 µm. C, SAN preparations from a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green, a marker for the SAN) and HCN1 (red). Scale bar, 500 µm. D, Magnification of the central SAN area of a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green) and HCN1 (red). Scale bar, 20 µm.
    Rat Monoclonal Antibody To Hcn4, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 47 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rat monoclonal antibody to hcn4/product/Santa Cruz Biotechnology
    Average 93 stars, based on 47 article reviews
    rat monoclonal antibody to hcn4 - by Bioz Stars, 2026-06
    93/100 stars

    Images

    1) Product Images from "Sick Sinus Syndrome in HCN1-Deficient Mice"

    Article Title: Sick Sinus Syndrome in HCN1-Deficient Mice

    Journal: Circulation

    doi: 10.1161/circulationaha.113.003712

    Figure 2. HCN1 is a major component of If in the sinoatrial node (SAN). A, HCN channel expression in SAN and atrial tissue (AT). HCN1 protein is present in wild-type (WT) and absent in HCN1−/− SAN (top). The same Western blot was reprobed for HCN4 and HCN2 (middle). Tubulin served as loading control (bottom). B, Whole-mount SAN preparation of a WT mouse depicting the central SAN area, crista terminalis (CT), superior vena cava (SVC), right atrium (RA), and septum (SEP). Scale bar, 500 µm. C, SAN preparations from a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green, a marker for the SAN) and HCN1 (red). Scale bar, 500 µm. D, Magnification of the central SAN area of a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green) and HCN1 (red). Scale bar, 20 µm.
    Figure Legend Snippet: Figure 2. HCN1 is a major component of If in the sinoatrial node (SAN). A, HCN channel expression in SAN and atrial tissue (AT). HCN1 protein is present in wild-type (WT) and absent in HCN1−/− SAN (top). The same Western blot was reprobed for HCN4 and HCN2 (middle). Tubulin served as loading control (bottom). B, Whole-mount SAN preparation of a WT mouse depicting the central SAN area, crista terminalis (CT), superior vena cava (SVC), right atrium (RA), and septum (SEP). Scale bar, 500 µm. C, SAN preparations from a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green, a marker for the SAN) and HCN1 (red). Scale bar, 500 µm. D, Magnification of the central SAN area of a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green) and HCN1 (red). Scale bar, 20 µm.

    Techniques Used: Expressing, Western Blot, Control, Staining, Marker



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    rat monoclonal antibody to hcn4  (Santa Cruz Biotechnology)
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    Santa Cruz Biotechnology rat monoclonal antibody to hcn4
    Figure 2. HCN1 is a major component of If in the sinoatrial node (SAN). A, HCN channel expression in SAN and atrial tissue (AT). HCN1 protein is present in wild-type (WT) and absent in HCN1−/− SAN (top). The same Western blot was reprobed for <t>HCN4</t> and HCN2 (middle). Tubulin served as loading control (bottom). B, Whole-mount SAN preparation of a WT mouse depicting the central SAN area, crista terminalis (CT), superior vena cava (SVC), right atrium (RA), and septum (SEP). Scale bar, 500 µm. C, SAN preparations from a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green, a marker for the SAN) and HCN1 (red). Scale bar, 500 µm. D, Magnification of the central SAN area of a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green) and HCN1 (red). Scale bar, 20 µm.
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    rat monoclonal α hcn4  (Santa Cruz Biotechnology)
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    Figure 2. HCN1 is a major component of If in the sinoatrial node (SAN). A, HCN channel expression in SAN and atrial tissue (AT). HCN1 protein is present in wild-type (WT) and absent in HCN1−/− SAN (top). The same Western blot was reprobed for <t>HCN4</t> and HCN2 (middle). Tubulin served as loading control (bottom). B, Whole-mount SAN preparation of a WT mouse depicting the central SAN area, crista terminalis (CT), superior vena cava (SVC), right atrium (RA), and septum (SEP). Scale bar, 500 µm. C, SAN preparations from a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green, a marker for the SAN) and HCN1 (red). Scale bar, 500 µm. D, Magnification of the central SAN area of a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green) and HCN1 (red). Scale bar, 20 µm.
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    Image Search Results


    Figure 2. HCN1 is a major component of If in the sinoatrial node (SAN). A, HCN channel expression in SAN and atrial tissue (AT). HCN1 protein is present in wild-type (WT) and absent in HCN1−/− SAN (top). The same Western blot was reprobed for HCN4 and HCN2 (middle). Tubulin served as loading control (bottom). B, Whole-mount SAN preparation of a WT mouse depicting the central SAN area, crista terminalis (CT), superior vena cava (SVC), right atrium (RA), and septum (SEP). Scale bar, 500 µm. C, SAN preparations from a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green, a marker for the SAN) and HCN1 (red). Scale bar, 500 µm. D, Magnification of the central SAN area of a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green) and HCN1 (red). Scale bar, 20 µm.

    Journal: Circulation

    Article Title: Sick Sinus Syndrome in HCN1-Deficient Mice

    doi: 10.1161/circulationaha.113.003712

    Figure Lengend Snippet: Figure 2. HCN1 is a major component of If in the sinoatrial node (SAN). A, HCN channel expression in SAN and atrial tissue (AT). HCN1 protein is present in wild-type (WT) and absent in HCN1−/− SAN (top). The same Western blot was reprobed for HCN4 and HCN2 (middle). Tubulin served as loading control (bottom). B, Whole-mount SAN preparation of a WT mouse depicting the central SAN area, crista terminalis (CT), superior vena cava (SVC), right atrium (RA), and septum (SEP). Scale bar, 500 µm. C, SAN preparations from a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green, a marker for the SAN) and HCN1 (red). Scale bar, 500 µm. D, Magnification of the central SAN area of a WT mouse (top) and HCN1−/− mouse (bottom) stained for HCN4 (green) and HCN1 (red). Scale bar, 20 µm.

    Article Snippet: Tissues of WT (n=5) and HCN1−/− (n=5) mice were stained with rat monoclonal antibody to HCN4 (1:100; Santa Cruz Biotechnology) and rabbit monoclonal antibody to HCN1 (1:100; Alomone Labs, Jerusalem, Israel).

    Techniques: Expressing, Western Blot, Control, Staining, Marker