Structured Review

Merck KGaA anti nav1 7
a Western blotting of <t>Nav1.7</t> using the total protein from ipsilateral L4-L6 DRGs of SMIR surgery rats, statistical summaries of western blot analysis: The expression of Nav1.7 protein was increased on days 10,15 and 20 after SMIR surgery (* P < 0.05,** P < 0.01, *** P < 0.001 vs naive group; n = 3). b - c Effect of pretreatment with i.t injection of ProTx-II (once daily from 1d before surgery until 7d after surgery) on the mechanical hyperalgesia induced by SMIR model rats. The result showed that selective Nav1.7 channel blocker can significantly reduced hyperalgesia induced by SMIR in a dose dependent way (* P < 0.05, *** P < 0.001 vs SMIR group; n = 6)
Anti Nav1 7, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti nav1 7/product/Merck KGaA
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
anti nav1 7 - by Bioz Stars, 2023-02
86/100 stars

Images

1) Product Images from "Membrane protein Nav1.7 contributes to the persistent post-surgical pain regulated by p-p65 in dorsal root ganglion (DRG) of SMIR rats model"

Article Title: Membrane protein Nav1.7 contributes to the persistent post-surgical pain regulated by p-p65 in dorsal root ganglion (DRG) of SMIR rats model

Journal: BMC Anesthesiology

doi: 10.1186/s12871-017-0438-8

a Western blotting of Nav1.7 using the total protein from ipsilateral L4-L6 DRGs of SMIR surgery rats, statistical summaries of western blot analysis: The expression of Nav1.7 protein was increased on days 10,15 and 20 after SMIR surgery (* P < 0.05,** P < 0.01, *** P < 0.001 vs naive group; n = 3). b - c Effect of pretreatment with i.t injection of ProTx-II (once daily from 1d before surgery until 7d after surgery) on the mechanical hyperalgesia induced by SMIR model rats. The result showed that selective Nav1.7 channel blocker can significantly reduced hyperalgesia induced by SMIR in a dose dependent way (* P < 0.05, *** P < 0.001 vs SMIR group; n = 6)
Figure Legend Snippet: a Western blotting of Nav1.7 using the total protein from ipsilateral L4-L6 DRGs of SMIR surgery rats, statistical summaries of western blot analysis: The expression of Nav1.7 protein was increased on days 10,15 and 20 after SMIR surgery (* P < 0.05,** P < 0.01, *** P < 0.001 vs naive group; n = 3). b - c Effect of pretreatment with i.t injection of ProTx-II (once daily from 1d before surgery until 7d after surgery) on the mechanical hyperalgesia induced by SMIR model rats. The result showed that selective Nav1.7 channel blocker can significantly reduced hyperalgesia induced by SMIR in a dose dependent way (* P < 0.05, *** P < 0.001 vs SMIR group; n = 6)

Techniques Used: Western Blot, Expressing, Injection

a Double immunofluorescence staining (The ipsilateral DRGs after 10d of SMIR group rats were used). b The distribution of Nav1.7 positive cells diameter (DRG from 3 rats)
Figure Legend Snippet: a Double immunofluorescence staining (The ipsilateral DRGs after 10d of SMIR group rats were used). b The distribution of Nav1.7 positive cells diameter (DRG from 3 rats)

Techniques Used: Double Immunofluorescence Staining

a - b Western blotting result of Nav1.7 from ipsilateral L4–6 DRGs of SMIR rats. Statistical summary of the densitometric analysis: compared to SMIR group, pretreatment with PDTC can inhibit the up-regulation of Nav1.7 at 10d and 15d after surgery (* P < 0.05,** P < 0.01 vs incision group; ### P < 0.001 vs SMIR group, n = 3). c Double immunofluorescence staining of ipsilateral DRG (10d after SMIR surgery). d Products of PCR amplifications for P1 - P9 from the SCN9A proximal promoter region was separated by 1% agarose gel electrophoresis
Figure Legend Snippet: a - b Western blotting result of Nav1.7 from ipsilateral L4–6 DRGs of SMIR rats. Statistical summary of the densitometric analysis: compared to SMIR group, pretreatment with PDTC can inhibit the up-regulation of Nav1.7 at 10d and 15d after surgery (* P < 0.05,** P < 0.01 vs incision group; ### P < 0.001 vs SMIR group, n = 3). c Double immunofluorescence staining of ipsilateral DRG (10d after SMIR surgery). d Products of PCR amplifications for P1 - P9 from the SCN9A proximal promoter region was separated by 1% agarose gel electrophoresis

Techniques Used: Western Blot, Double Immunofluorescence Staining, Agarose Gel Electrophoresis


Structured Review

Merck KGaA anti nav1 7
a Western blotting of <t>Nav1.7</t> using the total protein from ipsilateral L4-L6 DRGs of SMIR surgery rats, statistical summaries of western blot analysis: The expression of Nav1.7 protein was increased on days 10,15 and 20 after SMIR surgery (* P < 0.05,** P < 0.01, *** P < 0.001 vs naive group; n = 3). b - c Effect of pretreatment with i.t injection of ProTx-II (once daily from 1d before surgery until 7d after surgery) on the mechanical hyperalgesia induced by SMIR model rats. The result showed that selective Nav1.7 channel blocker can significantly reduced hyperalgesia induced by SMIR in a dose dependent way (* P < 0.05, *** P < 0.001 vs SMIR group; n = 6)
Anti Nav1 7, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti nav1 7/product/Merck KGaA
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
anti nav1 7 - by Bioz Stars, 2023-02
86/100 stars

Images

1) Product Images from "Membrane protein Nav1.7 contributes to the persistent post-surgical pain regulated by p-p65 in dorsal root ganglion (DRG) of SMIR rats model"

Article Title: Membrane protein Nav1.7 contributes to the persistent post-surgical pain regulated by p-p65 in dorsal root ganglion (DRG) of SMIR rats model

Journal: BMC Anesthesiology

doi: 10.1186/s12871-017-0438-8

a Western blotting of Nav1.7 using the total protein from ipsilateral L4-L6 DRGs of SMIR surgery rats, statistical summaries of western blot analysis: The expression of Nav1.7 protein was increased on days 10,15 and 20 after SMIR surgery (* P < 0.05,** P < 0.01, *** P < 0.001 vs naive group; n = 3). b - c Effect of pretreatment with i.t injection of ProTx-II (once daily from 1d before surgery until 7d after surgery) on the mechanical hyperalgesia induced by SMIR model rats. The result showed that selective Nav1.7 channel blocker can significantly reduced hyperalgesia induced by SMIR in a dose dependent way (* P < 0.05, *** P < 0.001 vs SMIR group; n = 6)
Figure Legend Snippet: a Western blotting of Nav1.7 using the total protein from ipsilateral L4-L6 DRGs of SMIR surgery rats, statistical summaries of western blot analysis: The expression of Nav1.7 protein was increased on days 10,15 and 20 after SMIR surgery (* P < 0.05,** P < 0.01, *** P < 0.001 vs naive group; n = 3). b - c Effect of pretreatment with i.t injection of ProTx-II (once daily from 1d before surgery until 7d after surgery) on the mechanical hyperalgesia induced by SMIR model rats. The result showed that selective Nav1.7 channel blocker can significantly reduced hyperalgesia induced by SMIR in a dose dependent way (* P < 0.05, *** P < 0.001 vs SMIR group; n = 6)

Techniques Used: Western Blot, Expressing, Injection

a Double immunofluorescence staining (The ipsilateral DRGs after 10d of SMIR group rats were used). b The distribution of Nav1.7 positive cells diameter (DRG from 3 rats)
Figure Legend Snippet: a Double immunofluorescence staining (The ipsilateral DRGs after 10d of SMIR group rats were used). b The distribution of Nav1.7 positive cells diameter (DRG from 3 rats)

Techniques Used: Double Immunofluorescence Staining

a - b Western blotting result of Nav1.7 from ipsilateral L4–6 DRGs of SMIR rats. Statistical summary of the densitometric analysis: compared to SMIR group, pretreatment with PDTC can inhibit the up-regulation of Nav1.7 at 10d and 15d after surgery (* P < 0.05,** P < 0.01 vs incision group; ### P < 0.001 vs SMIR group, n = 3). c Double immunofluorescence staining of ipsilateral DRG (10d after SMIR surgery). d Products of PCR amplifications for P1 - P9 from the SCN9A proximal promoter region was separated by 1% agarose gel electrophoresis
Figure Legend Snippet: a - b Western blotting result of Nav1.7 from ipsilateral L4–6 DRGs of SMIR rats. Statistical summary of the densitometric analysis: compared to SMIR group, pretreatment with PDTC can inhibit the up-regulation of Nav1.7 at 10d and 15d after surgery (* P < 0.05,** P < 0.01 vs incision group; ### P < 0.001 vs SMIR group, n = 3). c Double immunofluorescence staining of ipsilateral DRG (10d after SMIR surgery). d Products of PCR amplifications for P1 - P9 from the SCN9A proximal promoter region was separated by 1% agarose gel electrophoresis

Techniques Used: Western Blot, Double Immunofluorescence Staining, Agarose Gel Electrophoresis