pro bdnf  (Alomone Labs)


Bioz Verified Symbol Alomone Labs is a verified supplier
Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    Alomone Labs pro bdnf
    Upregulation of <t>pro-BDNF</t> expression by 12 weeks of HFD feeding (A) <t>Immunoblot</t> analysis of BDNF, TH and p-HSL expression in epididymal white adipose tissue (eWAT) mice fed with high fat diet and chow diet for 12 weeks. (n = 6, mean ± S.E.M, *p
    Pro Bdnf, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 26 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pro bdnf/product/Alomone Labs
    Average 94 stars, based on 26 article reviews
    Price from $9.99 to $1999.99
    pro bdnf - by Bioz Stars, 2022-11
    94/100 stars

    Images

    1) Product Images from "Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction"

    Article Title: Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction

    Journal: Aging and Disease

    doi: 10.14336/AD.2019.0810

    Upregulation of pro-BDNF expression by 12 weeks of HFD feeding (A) Immunoblot analysis of BDNF, TH and p-HSL expression in epididymal white adipose tissue (eWAT) mice fed with high fat diet and chow diet for 12 weeks. (n = 6, mean ± S.E.M, *p
    Figure Legend Snippet: Upregulation of pro-BDNF expression by 12 weeks of HFD feeding (A) Immunoblot analysis of BDNF, TH and p-HSL expression in epididymal white adipose tissue (eWAT) mice fed with high fat diet and chow diet for 12 weeks. (n = 6, mean ± S.E.M, *p

    Techniques Used: Expressing, Mouse Assay

    Age-dependent increase in pro-BDNF expression was associated with reduction in sympathetic innervation and mitochondrial activity in eWAT. (A) Immunoblot analysis of BDNF, TH and p-HSL expression in epididymal white adipose tissue (eWAT) of mice at the indicated ages. (n = 4, mean ± S.E.M, **p
    Figure Legend Snippet: Age-dependent increase in pro-BDNF expression was associated with reduction in sympathetic innervation and mitochondrial activity in eWAT. (A) Immunoblot analysis of BDNF, TH and p-HSL expression in epididymal white adipose tissue (eWAT) of mice at the indicated ages. (n = 4, mean ± S.E.M, **p

    Techniques Used: Expressing, Activity Assay, Mouse Assay

    The major cellular source of pro-BDNF expression in eWAT is PDGFRα + adipocyte progenitors. (A) quantitative PCR analysis of Bdnf expression in adipocytes and PDGFRA + cells isolated from eWAT of mice at the indicated ages (n = 3, mean ± S.E.M, ***p
    Figure Legend Snippet: The major cellular source of pro-BDNF expression in eWAT is PDGFRα + adipocyte progenitors. (A) quantitative PCR analysis of Bdnf expression in adipocytes and PDGFRA + cells isolated from eWAT of mice at the indicated ages (n = 3, mean ± S.E.M, ***p

    Techniques Used: Expressing, Real-time Polymerase Chain Reaction, Isolation, Mouse Assay

    PDGFRα + cell-specific KO reduced apoptosis and necroptosis in eWAT of mice with advanced age. (A) Quantitative PCR analysis of eWAT of BDNF pdgfra KO and WT mice at the indicated ages. (n = 5, mean ± S.E.M, *p
    Figure Legend Snippet: PDGFRα + cell-specific KO reduced apoptosis and necroptosis in eWAT of mice with advanced age. (A) Quantitative PCR analysis of eWAT of BDNF pdgfra KO and WT mice at the indicated ages. (n = 5, mean ± S.E.M, *p

    Techniques Used: Mouse Assay, Real-time Polymerase Chain Reaction

    PDGFRα + cell-specific KO reduced inflammatory and senescence marker expression in eWAT and insulin resistance of mice with advanced age. (A) Immunoblot analysis of BDNF and TH expression in epididymal white adipose tissue (eWAT) of BDNF pdgfra KO and WT mice at the indicated ages. (n = 5 per condition, mean ± S.E.M, *p
    Figure Legend Snippet: PDGFRα + cell-specific KO reduced inflammatory and senescence marker expression in eWAT and insulin resistance of mice with advanced age. (A) Immunoblot analysis of BDNF and TH expression in epididymal white adipose tissue (eWAT) of BDNF pdgfra KO and WT mice at the indicated ages. (n = 5 per condition, mean ± S.E.M, *p

    Techniques Used: Marker, Expressing, Mouse Assay

    BDNF expression was upregulated in epididymal adipose tissue with advanced age, but not in brown adipose tissue and inguinal white adipose tissue. (A-D) Immunoblot analysis of BDNF and senescence marker expression in supra-scapular brown adipose tissue (BAT), epididymal white adipose tissue (eWAT), and inguinal white adipose tissue (iWAT) of mice at the indicated ages. N= 4, mean ± S.E.M, p value was calculated by t-test (Full length blots in supplementary Fig. 2 ).
    Figure Legend Snippet: BDNF expression was upregulated in epididymal adipose tissue with advanced age, but not in brown adipose tissue and inguinal white adipose tissue. (A-D) Immunoblot analysis of BDNF and senescence marker expression in supra-scapular brown adipose tissue (BAT), epididymal white adipose tissue (eWAT), and inguinal white adipose tissue (iWAT) of mice at the indicated ages. N= 4, mean ± S.E.M, p value was calculated by t-test (Full length blots in supplementary Fig. 2 ).

    Techniques Used: Expressing, Marker, Mouse Assay

    2) Product Images from "Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction"

    Article Title: Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction

    Journal: Aging and Disease

    doi: 10.14336/AD.2019.0810

    The major cellular source of pro-BDNF expression in eWAT is PDGFRα + adipocyte progenitors. (A) quantitative PCR analysis of Bdnf expression in adipocytes and PDGFRA + cells isolated from eWAT of mice at the indicated ages (n = 3, mean ± S.E.M, ***p
    Figure Legend Snippet: The major cellular source of pro-BDNF expression in eWAT is PDGFRα + adipocyte progenitors. (A) quantitative PCR analysis of Bdnf expression in adipocytes and PDGFRA + cells isolated from eWAT of mice at the indicated ages (n = 3, mean ± S.E.M, ***p

    Techniques Used: Expressing, Real-time Polymerase Chain Reaction, Isolation, Mouse Assay

    PDGFRα + cell-specific KO reduced apoptosis and necroptosis in eWAT of mice with advanced age. (A) Quantitative PCR analysis of eWAT of BDNF pdgfra KO and WT mice at the indicated ages. (n = 5, mean ± S.E.M, *p
    Figure Legend Snippet: PDGFRα + cell-specific KO reduced apoptosis and necroptosis in eWAT of mice with advanced age. (A) Quantitative PCR analysis of eWAT of BDNF pdgfra KO and WT mice at the indicated ages. (n = 5, mean ± S.E.M, *p

    Techniques Used: Mouse Assay, Real-time Polymerase Chain Reaction

    PDGFRα + cell-specific KO reduced inflammatory and senescence marker expression in eWAT and insulin resistance of mice with advanced age. (A) Immunoblot analysis of BDNF and TH expression in epididymal white adipose tissue (eWAT) of BDNF pdgfra KO and WT mice at the indicated ages. (n = 5 per condition, mean ± S.E.M, *p
    Figure Legend Snippet: PDGFRα + cell-specific KO reduced inflammatory and senescence marker expression in eWAT and insulin resistance of mice with advanced age. (A) Immunoblot analysis of BDNF and TH expression in epididymal white adipose tissue (eWAT) of BDNF pdgfra KO and WT mice at the indicated ages. (n = 5 per condition, mean ± S.E.M, *p

    Techniques Used: Marker, Expressing, Mouse Assay

    3) Product Images from "Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction"

    Article Title: Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction

    Journal: Aging and Disease

    doi: 10.14336/AD.2019.0810

    PDGFRα + cell-specific KO reduced apoptosis and necroptosis in eWAT of mice with advanced age. (A) Quantitative PCR analysis of eWAT of BDNF pdgfra KO and WT mice at the indicated ages. (n = 5, mean ± S.E.M, *p
    Figure Legend Snippet: PDGFRα + cell-specific KO reduced apoptosis and necroptosis in eWAT of mice with advanced age. (A) Quantitative PCR analysis of eWAT of BDNF pdgfra KO and WT mice at the indicated ages. (n = 5, mean ± S.E.M, *p

    Techniques Used: Mouse Assay, Real-time Polymerase Chain Reaction

    4) Product Images from "Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction"

    Article Title: Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction

    Journal: Aging and Disease

    doi: 10.14336/AD.2019.0810

    PDGFRα + cell-specific KO reduced apoptosis and necroptosis in eWAT of mice with advanced age. (A) Quantitative PCR analysis of eWAT of BDNF pdgfra KO and WT mice at the indicated ages. (n = 5, mean ± S.E.M, *p
    Figure Legend Snippet: PDGFRα + cell-specific KO reduced apoptosis and necroptosis in eWAT of mice with advanced age. (A) Quantitative PCR analysis of eWAT of BDNF pdgfra KO and WT mice at the indicated ages. (n = 5, mean ± S.E.M, *p

    Techniques Used: Mouse Assay, Real-time Polymerase Chain Reaction

    5) Product Images from "Anti-apoptotic role and clinical relevance of neurotrophins in diffuse large B-cell lymphomas"

    Article Title: Anti-apoptotic role and clinical relevance of neurotrophins in diffuse large B-cell lymphomas

    Journal: British Journal of Cancer

    doi: 10.1038/bjc.2015.274

    A BDNF neurotrophin axis is functional in DLBCL cell lines. Effect of neutralisation of endogenous BDNF (with anti-BDNF, 15 μ g ml −1 ) or p75 NTR signalling (with anti-p75 NTR neutralising antibodies, 1 and 10 ng ml −1 ) and exogenous pro-BDNF (1 and 10 ng ml −1 ) was analysed on DLBCL cells during 72 h. ( A ) Viability of cells exposed to anti-BDNF or pro-BDNF or anti-p75 NTR was evaluated in reference to rituximab response (1 μ g ml −1 ) using the XTT metabolic test. Data obtained on GCB DLBCL cells after 72 h exposure are done as means±s.d. of relative cell viability (ratio) related to control obtained from seven independent experiments. Student t -test was used to determine significance, * P
    Figure Legend Snippet: A BDNF neurotrophin axis is functional in DLBCL cell lines. Effect of neutralisation of endogenous BDNF (with anti-BDNF, 15 μ g ml −1 ) or p75 NTR signalling (with anti-p75 NTR neutralising antibodies, 1 and 10 ng ml −1 ) and exogenous pro-BDNF (1 and 10 ng ml −1 ) was analysed on DLBCL cells during 72 h. ( A ) Viability of cells exposed to anti-BDNF or pro-BDNF or anti-p75 NTR was evaluated in reference to rituximab response (1 μ g ml −1 ) using the XTT metabolic test. Data obtained on GCB DLBCL cells after 72 h exposure are done as means±s.d. of relative cell viability (ratio) related to control obtained from seven independent experiments. Student t -test was used to determine significance, * P

    Techniques Used: Functional Assay

    In vivo efficacy of K252a in a DLBCL xenograft model. For the GCB-DLBCL xenograft model, SCID mice were injected with 1 × 10 7 SUDHL4 cells subcutaneously. ( A ) The human SUDHL4 cell origin of tumours was confirmed by immunohistochemistry (with anti-human CD20) and representative stainings for NGF, BDNF, Trk, and p75 NTR receptor are done (× 400). ( B ) After the tumours had become established (∼6 weeks after tumour inoculation), mice were treated with vehicle (Controls, n =10), K252a (0.5 mg kg −1 , n =10) or rituximab (25 mg kg −1 , n =5) or both agents ( n =8) for 3 weeks. Results are expressed as mean tumour volumes (cm 3 )±s.d. *, ** P
    Figure Legend Snippet: In vivo efficacy of K252a in a DLBCL xenograft model. For the GCB-DLBCL xenograft model, SCID mice were injected with 1 × 10 7 SUDHL4 cells subcutaneously. ( A ) The human SUDHL4 cell origin of tumours was confirmed by immunohistochemistry (with anti-human CD20) and representative stainings for NGF, BDNF, Trk, and p75 NTR receptor are done (× 400). ( B ) After the tumours had become established (∼6 weeks after tumour inoculation), mice were treated with vehicle (Controls, n =10), K252a (0.5 mg kg −1 , n =10) or rituximab (25 mg kg −1 , n =5) or both agents ( n =8) for 3 weeks. Results are expressed as mean tumour volumes (cm 3 )±s.d. *, ** P

    Techniques Used: In Vivo, Mouse Assay, Injection, Immunohistochemistry

    6) Product Images from "Matrix Metalloproteinase-9 Contributes to Kindled Seizure Development in Pentylenetetrazole-Treated Mice by Converting Pro-BDNF to Mature BDNF in the Hippocampus"

    Article Title: Matrix Metalloproteinase-9 Contributes to Kindled Seizure Development in Pentylenetetrazole-Treated Mice by Converting Pro-BDNF to Mature BDNF in the Hippocampus

    Journal: The Journal of Neuroscience

    doi: 10.1523/JNEUROSCI.3118-11.2011

    BDNF mRNA and mature BDNF protein expression in the mouse hippocampus. A–C , Mice were administered PTZ 11 times at a dose of 35 mg/kg and killed 6 h after the final dose. Control animals are saline-treated wild-type mice. Values are means ± SE ( n = 5–6). * p
    Figure Legend Snippet: BDNF mRNA and mature BDNF protein expression in the mouse hippocampus. A–C , Mice were administered PTZ 11 times at a dose of 35 mg/kg and killed 6 h after the final dose. Control animals are saline-treated wild-type mice. Values are means ± SE ( n = 5–6). * p

    Techniques Used: Expressing, Mouse Assay

    Effects of TrkB-Fc and pro-BDNF on PTZ-induced kindling in wild-type and MMP-9 (−/−) mice. A , B , Mice received microinjections of TrkB-Fc or IgG 1 -Fc into the right ventricle 30 min before each PTZ treatment (25 mg/kg). Values are means ± SE ( n = 10 for A ; n = 8 for B ). * p
    Figure Legend Snippet: Effects of TrkB-Fc and pro-BDNF on PTZ-induced kindling in wild-type and MMP-9 (−/−) mice. A , B , Mice received microinjections of TrkB-Fc or IgG 1 -Fc into the right ventricle 30 min before each PTZ treatment (25 mg/kg). Values are means ± SE ( n = 10 for A ; n = 8 for B ). * p

    Techniques Used: Mouse Assay

    Similar Products

  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94
    Alomone Labs anti probdnf antibody
    Anti Probdnf Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti probdnf antibody/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    anti probdnf antibody - by Bioz Stars, 2022-11
    94/100 stars
      Buy from Supplier

    95
    Alomone Labs pro bdnf protein
    Pro Bdnf Protein, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pro bdnf protein/product/Alomone Labs
    Average 95 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    pro bdnf protein - by Bioz Stars, 2022-11
    95/100 stars
      Buy from Supplier

    92
    Alomone Labs pro bdnf
    Pro Bdnf, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pro bdnf/product/Alomone Labs
    Average 92 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    pro bdnf - by Bioz Stars, 2022-11
    92/100 stars
      Buy from Supplier

    Image Search Results