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human primary lung fibroblasts  (ATCC)


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    ATCC human primary lung fibroblasts
    Human Primary Lung Fibroblasts, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 961 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human primary lung fibroblasts/product/ATCC
    Average 99 stars, based on 961 article reviews
    human primary lung fibroblasts - by Bioz Stars, 2026-01
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    Identification of Mivebresib as an efficient and specific anti-SFT (Solitary Fibrous Tumor) agent. (a) Secondary high-throughput screening (HTS) was performed using the Moffitt-ns and immortalized lung <t>fibroblast</t> cells. The CTG effects of both cell lines under all four doses were plotted. The green line indicated the differences in suppression effects between Moffitt-ns and Lf > 40 %. The blue line indicated that the suppression effects at the highest dose should be > 50 % in Moffitt-ns cells. 3 compounds were shown (Mivebresib: green, Zinc Pyrithione: red, and TAK-901: yellow). (b-f) Confirmatory MTS assays were performed in two primary SFT cells (INT-SFT and IEC139) and two control LMS cells (SKUT-1 and CP0024). Only Mivebresib showed efficient and selective cell proliferation-suppressing effects in SFT cells. (): INT-SFT; (): IEC139; (): SKUT-1; (): CP0024.
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    Identification of Mivebresib as an efficient and specific anti-SFT (Solitary Fibrous Tumor) agent. (a) Secondary high-throughput screening (HTS) was performed using the Moffitt-ns and immortalized lung <t>fibroblast</t> cells. The CTG effects of both cell lines under all four doses were plotted. The green line indicated the differences in suppression effects between Moffitt-ns and Lf > 40 %. The blue line indicated that the suppression effects at the highest dose should be > 50 % in Moffitt-ns cells. 3 compounds were shown (Mivebresib: green, Zinc Pyrithione: red, and TAK-901: yellow). (b-f) Confirmatory MTS assays were performed in two primary SFT cells (INT-SFT and IEC139) and two control LMS cells (SKUT-1 and CP0024). Only Mivebresib showed efficient and selective cell proliferation-suppressing effects in SFT cells. (): INT-SFT; (): IEC139; (): SKUT-1; (): CP0024.
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    Identification of Mivebresib as an efficient and specific anti-SFT (Solitary Fibrous Tumor) agent. (a) Secondary high-throughput screening (HTS) was performed using the Moffitt-ns and immortalized lung <t>fibroblast</t> cells. The CTG effects of both cell lines under all four doses were plotted. The green line indicated the differences in suppression effects between Moffitt-ns and Lf > 40 %. The blue line indicated that the suppression effects at the highest dose should be > 50 % in Moffitt-ns cells. 3 compounds were shown (Mivebresib: green, Zinc Pyrithione: red, and TAK-901: yellow). (b-f) Confirmatory MTS assays were performed in two primary SFT cells (INT-SFT and IEC139) and two control LMS cells (SKUT-1 and CP0024). Only Mivebresib showed efficient and selective cell proliferation-suppressing effects in SFT cells. (): INT-SFT; (): IEC139; (): SKUT-1; (): CP0024.
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    Average 97 stars, based on 1 article reviews
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    human lung fibroblast cell line hlf  (ATCC)
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    ATCC human lung fibroblast cell line hlf
    Identification of Mivebresib as an efficient and specific anti-SFT (Solitary Fibrous Tumor) agent. (a) Secondary high-throughput screening (HTS) was performed using the Moffitt-ns and immortalized lung <t>fibroblast</t> cells. The CTG effects of both cell lines under all four doses were plotted. The green line indicated the differences in suppression effects between Moffitt-ns and Lf > 40 %. The blue line indicated that the suppression effects at the highest dose should be > 50 % in Moffitt-ns cells. 3 compounds were shown (Mivebresib: green, Zinc Pyrithione: red, and TAK-901: yellow). (b-f) Confirmatory MTS assays were performed in two primary SFT cells (INT-SFT and IEC139) and two control LMS cells (SKUT-1 and CP0024). Only Mivebresib showed efficient and selective cell proliferation-suppressing effects in SFT cells. (): INT-SFT; (): IEC139; (): SKUT-1; (): CP0024.
    Human Lung Fibroblast Cell Line Hlf, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human lung fibroblast cell line hlf/product/ATCC
    Average 97 stars, based on 1 article reviews
    human lung fibroblast cell line hlf - by Bioz Stars, 2026-01
    97/100 stars
    		  Buy from Supplier

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    Identification of Mivebresib as an efficient and specific anti-SFT (Solitary Fibrous Tumor) agent. (a) Secondary high-throughput screening (HTS) was performed using the Moffitt-ns and immortalized lung fibroblast cells. The CTG effects of both cell lines under all four doses were plotted. The green line indicated the differences in suppression effects between Moffitt-ns and Lf > 40 %. The blue line indicated that the suppression effects at the highest dose should be > 50 % in Moffitt-ns cells. 3 compounds were shown (Mivebresib: green, Zinc Pyrithione: red, and TAK-901: yellow). (b-f) Confirmatory MTS assays were performed in two primary SFT cells (INT-SFT and IEC139) and two control LMS cells (SKUT-1 and CP0024). Only Mivebresib showed efficient and selective cell proliferation-suppressing effects in SFT cells. (): INT-SFT; (): IEC139; (): SKUT-1; (): CP0024.

    Journal: Neoplasia (New York, N.Y.)

    Article Title: Identification of BET inhibitors (BETi) against solitary fibrous tumor (SFT) through high-throughput screening (HTS)

    doi: 10.1016/j.neo.2025.101244

    Figure Lengend Snippet: Identification of Mivebresib as an efficient and specific anti-SFT (Solitary Fibrous Tumor) agent. (a) Secondary high-throughput screening (HTS) was performed using the Moffitt-ns and immortalized lung fibroblast cells. The CTG effects of both cell lines under all four doses were plotted. The green line indicated the differences in suppression effects between Moffitt-ns and Lf > 40 %. The blue line indicated that the suppression effects at the highest dose should be > 50 % in Moffitt-ns cells. 3 compounds were shown (Mivebresib: green, Zinc Pyrithione: red, and TAK-901: yellow). (b-f) Confirmatory MTS assays were performed in two primary SFT cells (INT-SFT and IEC139) and two control LMS cells (SKUT-1 and CP0024). Only Mivebresib showed efficient and selective cell proliferation-suppressing effects in SFT cells. (): INT-SFT; (): IEC139; (): SKUT-1; (): CP0024.

    Article Snippet: The hTERT-immortalized human lung fibroblast cell line (Lf) was acquired from the American Type Culture Collection (catalog number: CRL-4058) and maintained at 37 °C, 100 % humidity, and 5 % CO 2 .

    Techniques: High Throughput Screening Assay, Control