primary antibodies for trim37 (Santa Cruz Biotechnology)
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Primary Antibodies For Trim37, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/primary antibodies for trim37/product/Santa Cruz Biotechnology
Average 92 stars, based on 1 article reviews
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1) Product Images from "TRIM37 promotes epithelial-mesenchymal transition in colorectal cancer"
Article Title: TRIM37 promotes epithelial-mesenchymal transition in colorectal cancer
Journal: Molecular Medicine Reports
doi: 10.3892/mmr.2017.6125

Figure Legend Snippet: mRNA and protein expression levels of TRIM37 are increased in CRC cells relative to normal cells. (A) The mRNA expression level of TRIM37 in 30 paired CRC samples and adjacent normal tissues was detected by reverse transcription-quantitative polymerase chain reaction. The TRIM37 expression was normalized to β-actin. *P<0.001. (B) Representative immunohistochemical images of TRIM37 in matched CRC tissues (lower panel) and adjacent non-cancerous tissues (upper panel). Magnification, ×200. (C) Western blot analysis was used to examine the protein expression level of TRIM37 in CRC samples and paired adjacent normal tissues. CRC, colorectal cancer; TRIM37, tripartite motif containing 37; T, CRC tissues; N, non-cancerous adjacent tissues.
Techniques Used: Expressing, Real-time Polymerase Chain Reaction, Immunohistochemical staining, Western Blot

Figure Legend Snippet: TRIM37 promotes the proliferation, migration and invasion abilities in CRC cells. (A) TRIM37-KD in SW620 cells inhibited cell proliferation, whereas TRIM37-OV in SW480 cells increased proliferation. *P<0.05. (B) Crystal violet assay was used to analyze the effects of TRIM37 on the growth of CRC cells. (C) Representative images of the wound healing assay of TRIM37-KD and TRIM37-OV cells with control. Magnification, ×200. (D) Representative images of the Transwell assays of TRIM37-KD and TRIM37-OV cells with control. Magnification, ×200. Data are representative of three independent experiments. CRC, colorectal cancer; TRIM37, tripartite motif containing 37; TRIM 37-KD, TRIM37 knockdown; TRIM37-OV, TRIM37 overexpression.
Techniques Used: Migration, Crystal Violet Assay, Wound Healing Assay, Over Expression

Figure Legend Snippet: TRIM37 promotes the invasion of colorectal cancer cells via EMT. (A) Reverse transcription-quantitative polymerase chain reaction was performed to determine the levels of several components that were involved in EMT. In the TRIM37-KD SW620 cells, N-CAD and VIM were downregulated, whereas E-CAD was upregulated. *P<0.05. (B) In the TRIM37-OV SW480 cells, N-CAD and VIM were upregulated, whereas E-CAD was downregulated. *P<0.05. (C) Western blot analysis demonstrated that, in TRIM37-KD SW620 cells, the epithelial marker E-CAD was upregulated, whereas N-CAD and VIM, the mesenchymal markers, were downregulated. (D) In TRIM37-OV SW480 cells, E-CAD was downregulated, whereas N-CAD and VIM were upregulated. TRIM37, tripartite motif containing 37; TRIM 37-KD, TRIM37 knockdown; TRIM37-OV, TRIM37 overexpression; E-CAD, E-cadherin; N-CAD, N-cadherin; VIM, vimentin.
Techniques Used: Real-time Polymerase Chain Reaction, Western Blot, Marker, Over Expression