pfoa  (Millipore)


Bioz Verified Symbol Millipore is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 96
    Name:
    Pentadecafluorooctanoic acid ammonium salt
    Description:

    Catalog Number:
    77262
    Price:
    None
    Buy from Supplier


    Structured Review

    Millipore pfoa
    Pentadecafluorooctanoic acid ammonium salt

    https://www.bioz.com/result/pfoa/product/Millipore
    Average 96 stars, based on 6 article reviews
    Price from $9.99 to $1999.99
    pfoa - by Bioz Stars, 2020-09
    96/100 stars

    Images

    1) Product Images from "Occurrence investigation of perfluorinated compounds in surface water from East Lake (Wuhan, China) upon rapid and selective magnetic solid-phase extraction"

    Article Title: Occurrence investigation of perfluorinated compounds in surface water from East Lake (Wuhan, China) upon rapid and selective magnetic solid-phase extraction

    Journal: Scientific Reports

    doi: 10.1038/srep38633

    Chromatograms of the mixed water sample spiked with 5 ng L −1 of PFCs extracted by ( A ) Fe 3 O 4 @SiO 2 -NH 2 F 13 and ( B ) Oasis-Wax, respectively. (1, 2) PFHxS, PFHpA, (3) PFOA, (4) PFOS, (5) PFNA, (6) PFDA, (7) PFUnDA, (8) PFDoDA, (9) PFTA.
    Figure Legend Snippet: Chromatograms of the mixed water sample spiked with 5 ng L −1 of PFCs extracted by ( A ) Fe 3 O 4 @SiO 2 -NH 2 F 13 and ( B ) Oasis-Wax, respectively. (1, 2) PFHxS, PFHpA, (3) PFOA, (4) PFOS, (5) PFNA, (6) PFDA, (7) PFUnDA, (8) PFDoDA, (9) PFTA.

    Techniques Used:

    2) Product Images from "Gene Expression Profiling in Wild-Type and PPARα-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPARα-Independent Effects"

    Article Title: Gene Expression Profiling in Wild-Type and PPARα-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPARα-Independent Effects

    Journal: PPAR Research

    doi: 10.1155/2010/794739

    Expression of a group of well characterized markers of PPAR α transactivation in WT and Null mice. The response to PFOS in WT mice was less robust than that previously observed for either PFOA or Wy14,643. Red or green correspond to average up- or down- regulation, respectively.
    Figure Legend Snippet: Expression of a group of well characterized markers of PPAR α transactivation in WT and Null mice. The response to PFOS in WT mice was less robust than that previously observed for either PFOA or Wy14,643. Red or green correspond to average up- or down- regulation, respectively.

    Techniques Used: Expressing, Mouse Assay

    3) Product Images from "Estrogen-Like Properties of Fluorotelomer Alcohols as Revealed by MCF-7 Breast Cancer Cell Proliferation"

    Article Title: Estrogen-Like Properties of Fluorotelomer Alcohols as Revealed by MCF-7 Breast Cancer Cell Proliferation

    Journal: Environmental Health Perspectives

    doi: 10.1289/ehp.8149

    Analysis of estrogenicity of E 2 ( A ), 4-NP ( B ), 6:2 FTOH ( C ), 8:2 FTOH ( D ), PFOS ( E ), and PFOA ( F ) by the E-screen assay in MCF-7 cells. 0.1% DMSO was the solvent control. Results are expressed as mean ± SD of three replicates for each data point.
    Figure Legend Snippet: Analysis of estrogenicity of E 2 ( A ), 4-NP ( B ), 6:2 FTOH ( C ), 8:2 FTOH ( D ), PFOS ( E ), and PFOA ( F ) by the E-screen assay in MCF-7 cells. 0.1% DMSO was the solvent control. Results are expressed as mean ± SD of three replicates for each data point.

    Techniques Used:

    Effect of perfluorinated chemicals on mRNA expression of estrogen-responsive genes in MCF-7 cells were treated with 0.1% DMSO, 1 nM E 2 , 10 μM 4-NP, 30 μM 6:2 FTOH, 10 μM 8:2 FTOH, 50 μM PFOS, 50 μM PFNA, 50 μM PFOA, or 10 nM TCDD. After exposure to the test compounds for 48 hr, mRNA levels of TFF1 ( A ), PGR ( B ), ESR1 ( C ), PDZK1 ( D ), and ERBB2 ( E ) were measured by real-time PCR and normalized using HPRT1 as an internal control. Results are means from three replicate measurements and are expressed as fold relative to 0.1% DMSO; error bars indicate SD. * p
    Figure Legend Snippet: Effect of perfluorinated chemicals on mRNA expression of estrogen-responsive genes in MCF-7 cells were treated with 0.1% DMSO, 1 nM E 2 , 10 μM 4-NP, 30 μM 6:2 FTOH, 10 μM 8:2 FTOH, 50 μM PFOS, 50 μM PFNA, 50 μM PFOA, or 10 nM TCDD. After exposure to the test compounds for 48 hr, mRNA levels of TFF1 ( A ), PGR ( B ), ESR1 ( C ), PDZK1 ( D ), and ERBB2 ( E ) were measured by real-time PCR and normalized using HPRT1 as an internal control. Results are means from three replicate measurements and are expressed as fold relative to 0.1% DMSO; error bars indicate SD. * p

    Techniques Used: Expressing, Real-time Polymerase Chain Reaction

    4) Product Images from "Stabilization of Liposomes by Perfluorinated Compounds"

    Article Title: Stabilization of Liposomes by Perfluorinated Compounds

    Journal: ACS Omega

    doi: 10.1021/acsomega.8b02448

    Normalized fluorescence emission spectra of Laurdan-loaded DMPC liposomes in buffer A after adding various concentrations of (a) PFOA, (b) PFOS, (c) PFHxS, (d) SHS, (e) SDS, and (f) CTAB. Laurdan-loaded DMPC liposomes (100 μg mL –1 ) in 10 mM HEPES, pH 7.6, and 100 mM NaCl.
    Figure Legend Snippet: Normalized fluorescence emission spectra of Laurdan-loaded DMPC liposomes in buffer A after adding various concentrations of (a) PFOA, (b) PFOS, (c) PFHxS, (d) SHS, (e) SDS, and (f) CTAB. Laurdan-loaded DMPC liposomes (100 μg mL –1 ) in 10 mM HEPES, pH 7.6, and 100 mM NaCl.

    Techniques Used: Fluorescence

    The structures of the three PFCs: (a) PFOA, (b) PFOS, and (c) PFHxS; three surfactants: (d) SDS, (e) SHS, and (f) CTAB; and three lipids: (g) DOPC, (h) DMPC, and (i) DPPC used in this study.
    Figure Legend Snippet: The structures of the three PFCs: (a) PFOA, (b) PFOS, and (c) PFHxS; three surfactants: (d) SDS, (e) SHS, and (f) CTAB; and three lipids: (g) DOPC, (h) DMPC, and (i) DPPC used in this study.

    Techniques Used:

    5) Product Images from "Perfluoroalkylated Substance Effects in Xenopuslaevis A6 Kidney Epithelial Cells Determined by ATR-FTIR Spectroscopy and Chemometric Analysis"

    Article Title: Perfluoroalkylated Substance Effects in Xenopuslaevis A6 Kidney Epithelial Cells Determined by ATR-FTIR Spectroscopy and Chemometric Analysis

    Journal: Chemical Research in Toxicology

    doi: 10.1021/acs.chemrestox.6b00076

    Effects of PFBS, PFNA, PFOS, and PFOA on dose- and time-related cell number increases in culture.
    Figure Legend Snippet: Effects of PFBS, PFNA, PFOS, and PFOA on dose- and time-related cell number increases in culture.

    Techniques Used:

    One-D PCA-LDA score plots showing dose–response effects of PFBS, PFOA, PFOS, and PFNA in the three experiments. *Most discriminant PFAS-treatment compared to the control.
    Figure Legend Snippet: One-D PCA-LDA score plots showing dose–response effects of PFBS, PFOA, PFOS, and PFNA in the three experiments. *Most discriminant PFAS-treatment compared to the control.

    Techniques Used:

    6) Product Images from "Nrf2- and PPAR?-Mediated Regulation of Hepatic Mrp Transporters after Exposure to Perfluorooctanoic Acid and Perfluorodecanoic Acid"

    Article Title: Nrf2- and PPAR?-Mediated Regulation of Hepatic Mrp Transporters after Exposure to Perfluorooctanoic Acid and Perfluorodecanoic Acid

    Journal:

    doi: 10.1093/toxsci/kfn177

    Mrps are induced by various PFCAs. Expression of Mrp3 and Mrp4 mRNA in liver 48 h after treatment with vehicle or 80 mg/kg PFDA or PFOA. Total RNA from livers of chemically treated male C57BL/6 mice ( n = 5 per treatment) was analyzed by the branched DNA
    Figure Legend Snippet: Mrps are induced by various PFCAs. Expression of Mrp3 and Mrp4 mRNA in liver 48 h after treatment with vehicle or 80 mg/kg PFDA or PFOA. Total RNA from livers of chemically treated male C57BL/6 mice ( n = 5 per treatment) was analyzed by the branched DNA

    Techniques Used: Expressing, Mouse Assay

    7) Product Images from "Stabilization of Liposomes by Perfluorinated Compounds"

    Article Title: Stabilization of Liposomes by Perfluorinated Compounds

    Journal: ACS Omega

    doi: 10.1021/acsomega.8b02448

    Normalized fluorescence emission spectra of Laurdan-loaded DMPC liposomes in buffer A after adding various concentrations of (a) PFOA, (b) PFOS, (c) PFHxS, (d) SHS, (e) SDS, and (f) CTAB. Laurdan-loaded DMPC liposomes (100 μg mL –1 ) in 10 mM HEPES, pH 7.6, and 100 mM NaCl.
    Figure Legend Snippet: Normalized fluorescence emission spectra of Laurdan-loaded DMPC liposomes in buffer A after adding various concentrations of (a) PFOA, (b) PFOS, (c) PFHxS, (d) SHS, (e) SDS, and (f) CTAB. Laurdan-loaded DMPC liposomes (100 μg mL –1 ) in 10 mM HEPES, pH 7.6, and 100 mM NaCl.

    Techniques Used: Fluorescence

    The structures of the three PFCs: (a) PFOA, (b) PFOS, and (c) PFHxS; three surfactants: (d) SDS, (e) SHS, and (f) CTAB; and three lipids: (g) DOPC, (h) DMPC, and (i) DPPC used in this study.
    Figure Legend Snippet: The structures of the three PFCs: (a) PFOA, (b) PFOS, and (c) PFHxS; three surfactants: (d) SDS, (e) SHS, and (f) CTAB; and three lipids: (g) DOPC, (h) DMPC, and (i) DPPC used in this study.

    Techniques Used:

    8) Product Images from "Behavioral, morphometric, and gene expression effects in adult zebrafish (Danio rerio) embryonically exposed to PFOA, PFOS, and PFNA"

    Article Title: Behavioral, morphometric, and gene expression effects in adult zebrafish (Danio rerio) embryonically exposed to PFOA, PFOS, and PFNA

    Journal: Aquatic toxicology (Amsterdam, Netherlands)

    doi: 10.1016/j.aquatox.2016.09.011

    Gene expression of adult (A) male and (B) female zebrafish embryonically exposed to PFOS, PFOA, or PFNA. Bars represent mean fold change and standard mean error. N = 8–10 fish per treatment per sex. An asterisk (*) indicates a statistical significant value, p
    Figure Legend Snippet: Gene expression of adult (A) male and (B) female zebrafish embryonically exposed to PFOS, PFOA, or PFNA. Bars represent mean fold change and standard mean error. N = 8–10 fish per treatment per sex. An asterisk (*) indicates a statistical significant value, p

    Techniques Used: Expressing, Fluorescence In Situ Hybridization

    9) Product Images from "Metabolically inert perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria"

    Article Title: Metabolically inert perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria

    Journal: Archives of Toxicology

    doi: 10.1007/s00204-015-1535-4

    Effect of PFOA/PFOS on mitochondrial swelling in brown-fat mitochondria. a Representative traces showing the effects of PFOA, PFOS and octanoic acid on non-specific mitochondrial permeabilization in brown-fat mitochondria isolated from wild-type mice. Pyruvate (5 mM) and 1 mM GDP were added before the start of the trace recording. Additions were 0.25 mg/ml brown-fat mitochondria, and at the end 0.02 mg/ml alamethicin ( Ala ) (to allow for full mitochondrial permeabilization). PFOA, PFOS and octanoic acid were successively added to concentrations 80–400 µM (each addition was 80 µM and recorded during 2.0–2.5 min). To allow for direct comparisons, all traces shown are from one experimental day. b Quantification of the amplitude of swelling exactly 2 min after the final addition (400 µM) of PFOA or PFOS or octanoic acid. Values are indicated in percent of the maximum response [defined as the absorbance difference between the starting value (0 concentration) and the value after alamethicin addition]. The points are mean ± SE of 3–5 independent mitochondrial preparations. *Indicates difference between intact mitochondria (swelling is equal to 0) and agent; # Difference between PFOS and other tested chemicals (one symbol indicates P
    Figure Legend Snippet: Effect of PFOA/PFOS on mitochondrial swelling in brown-fat mitochondria. a Representative traces showing the effects of PFOA, PFOS and octanoic acid on non-specific mitochondrial permeabilization in brown-fat mitochondria isolated from wild-type mice. Pyruvate (5 mM) and 1 mM GDP were added before the start of the trace recording. Additions were 0.25 mg/ml brown-fat mitochondria, and at the end 0.02 mg/ml alamethicin ( Ala ) (to allow for full mitochondrial permeabilization). PFOA, PFOS and octanoic acid were successively added to concentrations 80–400 µM (each addition was 80 µM and recorded during 2.0–2.5 min). To allow for direct comparisons, all traces shown are from one experimental day. b Quantification of the amplitude of swelling exactly 2 min after the final addition (400 µM) of PFOA or PFOS or octanoic acid. Values are indicated in percent of the maximum response [defined as the absorbance difference between the starting value (0 concentration) and the value after alamethicin addition]. The points are mean ± SE of 3–5 independent mitochondrial preparations. *Indicates difference between intact mitochondria (swelling is equal to 0) and agent; # Difference between PFOS and other tested chemicals (one symbol indicates P

    Techniques Used: Isolation, Mouse Assay, Concentration Assay

    Effect of PFOA/PFOS on membrane potential in brown-fat mitochondria. a Representative traces showing the effects of PFOA on membrane potential (safranin O absorbance) in brown-fat mitochondria isolated from UCP1 KO ( thin line ) or wild-type ( heavy line ) mice. 5 mM pyruvate and 1 mM GDP were added before start of trace recording. Further additions in a were 0.25 mg/ml brown-fat mitochondria ( BM ), 2 µM FCCP and 0.02 mg/ml alamethicin ( Ala ). PFOA was added successively to obtain concentrations of 80–400 µM (each addition was 80 µM). b Effect of increasing PFOA concentrations on membrane potential in brown-fat mitochondria from wild-type and UCP1 KO mice. Data from experiments as in a were recalculated as membrane potentials (detailed in (Nedergaard 1983 ; Shabalina et al. 2014 ). c Oxygen consumption as an effect of membrane potential. Data from b were plotted with the corresponding values for oxygen consumption. To allow for direct comparisons, all corresponding results are from one experimental day, with parallel mitochondrial preparations of wild-type and UCP1 KO mitochondria, examined in parallel for respiration (as in Fig. 1 ) and membrane potential. The points in b and c are mean ± SE of 4 independent mitochondrial preparations for WT and 2 preparations for UCP1 KO group. In b , asterisks indicate significant differences between wildtype and UCP1 KO mitochondria (one symbol P
    Figure Legend Snippet: Effect of PFOA/PFOS on membrane potential in brown-fat mitochondria. a Representative traces showing the effects of PFOA on membrane potential (safranin O absorbance) in brown-fat mitochondria isolated from UCP1 KO ( thin line ) or wild-type ( heavy line ) mice. 5 mM pyruvate and 1 mM GDP were added before start of trace recording. Further additions in a were 0.25 mg/ml brown-fat mitochondria ( BM ), 2 µM FCCP and 0.02 mg/ml alamethicin ( Ala ). PFOA was added successively to obtain concentrations of 80–400 µM (each addition was 80 µM). b Effect of increasing PFOA concentrations on membrane potential in brown-fat mitochondria from wild-type and UCP1 KO mice. Data from experiments as in a were recalculated as membrane potentials (detailed in (Nedergaard 1983 ; Shabalina et al. 2014 ). c Oxygen consumption as an effect of membrane potential. Data from b were plotted with the corresponding values for oxygen consumption. To allow for direct comparisons, all corresponding results are from one experimental day, with parallel mitochondrial preparations of wild-type and UCP1 KO mitochondria, examined in parallel for respiration (as in Fig. 1 ) and membrane potential. The points in b and c are mean ± SE of 4 independent mitochondrial preparations for WT and 2 preparations for UCP1 KO group. In b , asterisks indicate significant differences between wildtype and UCP1 KO mitochondria (one symbol P

    Techniques Used: Isolation, Mouse Assay

    PFOA-/PFOS-stimulated oxygen consumption: dependence on UCP1. Representative traces showing the effects of FCCP ( a ) and PFOA ( b ) on oxygen consumption in brown adipose tissue mitochondria ( M , 0.3 mg/ml) from UCP1 KO ( thin line ) or wild-type ( WT ) ( heavy line ) mice. Additions were 5 mM pyruvate ( Pyr ), 1 mM GDP, and 0.7–2.1 µM FCCP (added successively). PFOA was successively added in the concentration range 80–480 µM (each addition was 80 µM). c Compilation of the effect of PFOA, based on experiments as those shown in b . Concentration–response curve of PFOS ( d ) and octanoic acid ( e ) in brown-fat mitochondria from UCP1 KO or WT mice. Mitochondria were examined as shown for PFOA in b , except that not all concentrations of PFOS were examined in UCP1 KO. f UCP1-dependent effects of PFOA, PFOS, and octanoic acid on oxygen consumption. The values were obtained by subtraction of the means of effects in UCP1 KO mitochondria from the corresponding means of effects in wild-type mitochondria. The points in c – f are mean ± SE of 4–8 independent mitochondrial preparations for each group. *Difference between genotypes (two symbols P
    Figure Legend Snippet: PFOA-/PFOS-stimulated oxygen consumption: dependence on UCP1. Representative traces showing the effects of FCCP ( a ) and PFOA ( b ) on oxygen consumption in brown adipose tissue mitochondria ( M , 0.3 mg/ml) from UCP1 KO ( thin line ) or wild-type ( WT ) ( heavy line ) mice. Additions were 5 mM pyruvate ( Pyr ), 1 mM GDP, and 0.7–2.1 µM FCCP (added successively). PFOA was successively added in the concentration range 80–480 µM (each addition was 80 µM). c Compilation of the effect of PFOA, based on experiments as those shown in b . Concentration–response curve of PFOS ( d ) and octanoic acid ( e ) in brown-fat mitochondria from UCP1 KO or WT mice. Mitochondria were examined as shown for PFOA in b , except that not all concentrations of PFOS were examined in UCP1 KO. f UCP1-dependent effects of PFOA, PFOS, and octanoic acid on oxygen consumption. The values were obtained by subtraction of the means of effects in UCP1 KO mitochondria from the corresponding means of effects in wild-type mitochondria. The points in c – f are mean ± SE of 4–8 independent mitochondrial preparations for each group. *Difference between genotypes (two symbols P

    Techniques Used: Mouse Assay, Concentration Assay

    Effects of PFOA/PFOS on ROS production in brown-fat mitochondria. Mitochondrial H 2 O 2 net production was determined fluorometrically with the Amplex Red reagent as detailed in Methods. PFOA, PFOS or octanoic acid were added in aliquots of 80 µM to wild-type brown-fat mitochondria. The points are mean ± SE of 4–7 independent mitochondrial preparations. * Difference between 0 concentration and other concentrations of PFOA; ° Difference between 0 concentration and other concentrations of PFOS; # Indicates difference between PFOA/PFOS and octanoic acid (one symbol indicates P
    Figure Legend Snippet: Effects of PFOA/PFOS on ROS production in brown-fat mitochondria. Mitochondrial H 2 O 2 net production was determined fluorometrically with the Amplex Red reagent as detailed in Methods. PFOA, PFOS or octanoic acid were added in aliquots of 80 µM to wild-type brown-fat mitochondria. The points are mean ± SE of 4–7 independent mitochondrial preparations. * Difference between 0 concentration and other concentrations of PFOA; ° Difference between 0 concentration and other concentrations of PFOS; # Indicates difference between PFOA/PFOS and octanoic acid (one symbol indicates P

    Techniques Used: Concentration Assay

    10) Product Images from "Complete Defluorination of Perfluorinated Compounds by Hydrated Electrons Generated from 3-Indole-acetic-acid in Organomodified Montmorillonite"

    Article Title: Complete Defluorination of Perfluorinated Compounds by Hydrated Electrons Generated from 3-Indole-acetic-acid in Organomodified Montmorillonite

    Journal: Scientific Reports

    doi: 10.1038/srep32949

    Effect of initial pHs on ( a ) photodegradation and ( b ) defluorination of PFOA by 3-indole-acetic-acid under the irradiation of a mercury lamp as a function of time in the presence of HDTMA-montmorillonite. Experimental conditions: the initial concentrations of PFOA, IAA, and clay mineral were 10 mg L −1 , 1 mM and 2.2 g L −1 , respectively; pH was adjusted to 3.0, 4.0, 6.0, 8.0, 10.0 and 11.0 by NaOH and HCl, respectively; a 36 W low-pressure mercury lamp was used to provide light irradiation.
    Figure Legend Snippet: Effect of initial pHs on ( a ) photodegradation and ( b ) defluorination of PFOA by 3-indole-acetic-acid under the irradiation of a mercury lamp as a function of time in the presence of HDTMA-montmorillonite. Experimental conditions: the initial concentrations of PFOA, IAA, and clay mineral were 10 mg L −1 , 1 mM and 2.2 g L −1 , respectively; pH was adjusted to 3.0, 4.0, 6.0, 8.0, 10.0 and 11.0 by NaOH and HCl, respectively; a 36 W low-pressure mercury lamp was used to provide light irradiation.

    Techniques Used: Irradiation

    The production of short-chain perfluorinated acids as a function of irradiation time during the degradation of PFOA. Experimental conditions: the initial concentrations of PFOA, 3-indole-acetic-acid, and HDTMA-montmorillonite were 10 mg L −1 , 1 mM and 2.2 g L −1 , respectively; pH was adjusted to 6.0 by adding NaOH and HCl; a 36 W low-pressure mercury lamp was used to provide light irradiation.
    Figure Legend Snippet: The production of short-chain perfluorinated acids as a function of irradiation time during the degradation of PFOA. Experimental conditions: the initial concentrations of PFOA, 3-indole-acetic-acid, and HDTMA-montmorillonite were 10 mg L −1 , 1 mM and 2.2 g L −1 , respectively; pH was adjusted to 6.0 by adding NaOH and HCl; a 36 W low-pressure mercury lamp was used to provide light irradiation.

    Techniques Used: Irradiation

    ( a ) Photodegradation and ( b ) defluorination of PFOA by 3-indole-acetic-acid under the irradiation of a mercury lamp as a function of time in the presence of HDTMA-montmorillonite. Experimental conditions: the initial concentrations of PFOA, IAA, and clay mineral were 10 mg L −1 , 1 mM and 2.2 g L −1 , respectively; pH was adjusted to 6.0 by adding NaOH and HCl; a 36 W low-pressure mercury lamp was used to provide light irradiation.
    Figure Legend Snippet: ( a ) Photodegradation and ( b ) defluorination of PFOA by 3-indole-acetic-acid under the irradiation of a mercury lamp as a function of time in the presence of HDTMA-montmorillonite. Experimental conditions: the initial concentrations of PFOA, IAA, and clay mineral were 10 mg L −1 , 1 mM and 2.2 g L −1 , respectively; pH was adjusted to 6.0 by adding NaOH and HCl; a 36 W low-pressure mercury lamp was used to provide light irradiation.

    Techniques Used: Irradiation

    11) Product Images from "PFOS, PFNA, and PFOA Sub-Lethal Exposure to Embryonic Zebrafish Have Different Toxicity Profiles in Terms of Morphometrics, Behavior and Gene Expression"

    Article Title: PFOS, PFNA, and PFOA Sub-Lethal Exposure to Embryonic Zebrafish Have Different Toxicity Profiles in Terms of Morphometrics, Behavior and Gene Expression

    Journal: Aquatic toxicology (Amsterdam, Netherlands)

    doi: 10.1016/j.aquatox.2016.03.026

    Exposure timeline of embryonic zebrafish to PFOS, PFOA or PFNA. All exposures occurred between 3 and 120 hpf. Exposure time period is indicated by dashed line.
    Figure Legend Snippet: Exposure timeline of embryonic zebrafish to PFOS, PFOA or PFNA. All exposures occurred between 3 and 120 hpf. Exposure time period is indicated by dashed line.

    Techniques Used:

    Molecular structures of PFOS, PFOA, and PFNA. PFOS has an eight-carbon chain backbone with a sulfonate end group, PFOA has an eight-carbon chain backbone with a carboxyl end group, and PFNA has a nine-carbon chain backbone with a carboxyl end group.
    Figure Legend Snippet: Molecular structures of PFOS, PFOA, and PFNA. PFOS has an eight-carbon chain backbone with a sulfonate end group, PFOA has an eight-carbon chain backbone with a carboxyl end group, and PFNA has a nine-carbon chain backbone with a carboxyl end group.

    Techniques Used:

    Related Articles

    Polymerase Chain Reaction:

    Article Title: Gene Expression Profiling in Wild-Type and PPARα-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPARα-Independent Effects
    Article Snippet: .. PCR dose groups consisted of 4 animals per group and were treated for seven-days with either 10 mg/kg/day PFOS, 3 mg/kg/day PFOA (ammonium salt, catalog no. 77262, Sigma-Aldrich) in 0.5% Tween 20, or 50 mg/kg/day Wy-14,643 (catalog no. C7081, Sigma-Aldrich) in 0.5% methylcellulose, along with vehicle controls. ..

    Mouse Assay:

    Article Title: Hepatic and renal Bcrp transporter expression in mice treated with perfluorooctanoic acid
    Article Snippet: .. Mice (n=6) were dosed daily with vehicle (deionized water, 10 ml/kg), 1, or 3 mg/kg/day of perfluorooctanoic acid ammonium salt (77262, Sigma-Aldrich, St. Louis, MO) for seven days by oral gavage. .. PFOA doses and dosing regimen were previously used to investigate the regulation of hepatic nuclear receptor pathways in mice ( ).

    Similar Products

  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94
    Millipore perfluorooctanoic acid pfoa
    Perfluorooctanoic Acid Pfoa, supplied by Millipore, used in various techniques. Bioz Stars score: 94/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/perfluorooctanoic acid pfoa/product/Millipore
    Average 94 stars, based on 10 article reviews
    Price from $9.99 to $1999.99
    perfluorooctanoic acid pfoa - by Bioz Stars, 2020-09
    94/100 stars
      Buy from Supplier

    Image Search Results