patulin  (Millipore)


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  • 93
    Name:
    Patulin
    Description:

    Catalog Number:
    p1639
    Price:
    None
    Applications:
    Patulin is a mycotoxin produced by a variety of molds, such as, Aspergillus and Penicillium. It is commonly found in apples. It is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na+-K+ dependent ATPase and to induce intra- and intermolecular protein crosslinking. It is used to study patulin contamination of bottled wine, DNA-damaging activity of patulin in Escherichia coli, and molecular cloning and functional characterization of two CYP619 cytochrome P450s involved in biosynthesis of patulin in Aspergillus clavatus.
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    Structured Review

    Millipore patulin
    Patulin

    https://www.bioz.com/result/patulin/product/Millipore
    Average 93 stars, based on 7 article reviews
    Price from $9.99 to $1999.99
    patulin - by Bioz Stars, 2020-09
    93/100 stars

    Images

    Related Articles

    High Performance Liquid Chromatography:

    Article Title: A study on the physicochemical parameters for Penicillium expansum growth and patulin production: effect of temperature, pH, and water activity
    Article Snippet: .. Patulin extraction and HPLC analysis After the appropriate incubation period (7 days for the pH assays and 14 days for the temperature and a W assays), the agar medium was scraped off the Petri dishes overlaid with sterile cellophane, cut into strips, mixed with 50 mL of ethyl acetate (Sigma‐Aldrich, Saint‐Quentin Fallavier, France) and macerated with agitation (250 rpm) at room temperature on an orbital shaker (Ningbo Hinotek Technology, Zhejiang, China). ..

    Incubation:

    Article Title: A study on the physicochemical parameters for Penicillium expansum growth and patulin production: effect of temperature, pH, and water activity
    Article Snippet: .. Patulin extraction and HPLC analysis After the appropriate incubation period (7 days for the pH assays and 14 days for the temperature and a W assays), the agar medium was scraped off the Petri dishes overlaid with sterile cellophane, cut into strips, mixed with 50 mL of ethyl acetate (Sigma‐Aldrich, Saint‐Quentin Fallavier, France) and macerated with agitation (250 rpm) at room temperature on an orbital shaker (Ningbo Hinotek Technology, Zhejiang, China). ..

    other:

    Article Title: Patulin Degradation by the Biocontrol Yeast Sporobolomyces sp. Is an Inducible Process
    Article Snippet: Patulin Commercial standards of PAT were purchased from Sigma-Aldrich (Milan, Italy) and from A.G. Scientific, Inc. (San Diego, CA, USA).

    Article Title: Patulin Induced Oxidative Stress Mediated Apoptotic Damage in Mice, and its Modulation by Green Tea Leaves
    Article Snippet: Patulin (PAT, 4-hydroxy-4H-furo(3,2-C)pyran-2(6H)-one, purity > 98.0%) were obtained from Sigma (Bangalore, India), 5,5-dithiobis (2-nitrobenzoic acid) (DTNB) and HiSep LSM LS001 were procured from Hi-Media (Bangalore, India).

    Injection:

    Article Title: Sex-related variations in bone microstructure of rabbits intramuscularly exposed to patulin
    Article Snippet: .. In the groups E♂ (n = 3) and E♀ (n = 4), adult rabbits were intramuscularly injected with patulin (Sigma Aldrich, Munich, Germany) at dose 10 μg/kg bw dissolved in saline two times per week for 28 days. ..

    Construct:

    Article Title: A study on the physicochemical parameters for Penicillium expansum growth and patulin production: effect of temperature, pH, and water activity
    Article Snippet: .. A calibration curve was constructed with patulin standard (Sigma‐Aldrich) at concentrations ranging from 0.05 to 10 μg/mL. ..

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    Millipore fluvastatin
    Combined treatment with <t>fluvastatin</t> and zoledronate reverses astrocytic and retinal vascular defects in hGfap/Ccm3 cKO mice. ( A–D ) Representative images of coronal brain sections from wild-type control ( A and C ) and hGfap/Ccm3 cKO ( B and D ) neonates
    Fluvastatin, supplied by Millipore, used in various techniques. Bioz Stars score: 94/100, based on 20 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Millipore potassium phosphate monobasic
    Combined treatment with <t>fluvastatin</t> and zoledronate reverses astrocytic and retinal vascular defects in hGfap/Ccm3 cKO mice. ( A–D ) Representative images of coronal brain sections from wild-type control ( A and C ) and hGfap/Ccm3 cKO ( B and D ) neonates
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    99
    Millipore sepharose cl 4b
    Combined treatment with <t>fluvastatin</t> and zoledronate reverses astrocytic and retinal vascular defects in hGfap/Ccm3 cKO mice. ( A–D ) Representative images of coronal brain sections from wild-type control ( A and C ) and hGfap/Ccm3 cKO ( B and D ) neonates
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    Image Search Results


    Combined treatment with fluvastatin and zoledronate reverses astrocytic and retinal vascular defects in hGfap/Ccm3 cKO mice. ( A–D ) Representative images of coronal brain sections from wild-type control ( A and C ) and hGfap/Ccm3 cKO ( B and D ) neonates

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Combined HMG-COA reductase and prenylation inhibition in treatment of CCM

    doi: 10.1073/pnas.1702942114

    Figure Lengend Snippet: Combined treatment with fluvastatin and zoledronate reverses astrocytic and retinal vascular defects in hGfap/Ccm3 cKO mice. ( A–D ) Representative images of coronal brain sections from wild-type control ( A and C ) and hGfap/Ccm3 cKO ( B and D ) neonates

    Article Snippet: Drugs and inhibitors used were: cerivastatin (SML0005; Sigma), lovastatin (1530; Tocris), fluvastatin (344075; Calbiochem/EMD Chemicals), simvastatin (567021; Calbiochem/EMD Chemicals), mevastatin (26538076; Sigma), atorvastatin (PZ0001; Sigma), pravastatin (P4498; Sigma), pitavastatin (s1759; Selleckchem), fasudil (F-4660; LC Laboratories), zoledronate (L0223; Sigma), clodronate (D4434; Sigma); thiram (45689; Sigma), pyrithione zinc (H6377; Sigma), BAY11-7082 (196870; EMD Millipore), patulin (P1639; Sigma), mitoxantrone dihydrochloride (M6545; Sigma), zaragozic acid (17452; Cayman Chemical Company), GGTI-298 (G5169; Sigma), GGTI-286 (SML1186; Sigma), FTI-277 (F9803; Sigma), RKI-1447, GGTI-2417, and FTI-2153 (S.M.S.).

    Techniques: Mouse Assay

    The fluvastatin and zoledronate combination has no effect on KLF2/4 expression in Cdh5(PAC)CreERT2/Ccm3 cKO mice. ( A – F ) In situ hybridization with Klf2 ( A – C ) or Klf4 ( D – F ) on cerebellar sections of control ( A and D ) or Cdh5(PAC)CreERT2/Ccm3

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Combined HMG-COA reductase and prenylation inhibition in treatment of CCM

    doi: 10.1073/pnas.1702942114

    Figure Lengend Snippet: The fluvastatin and zoledronate combination has no effect on KLF2/4 expression in Cdh5(PAC)CreERT2/Ccm3 cKO mice. ( A – F ) In situ hybridization with Klf2 ( A – C ) or Klf4 ( D – F ) on cerebellar sections of control ( A and D ) or Cdh5(PAC)CreERT2/Ccm3

    Article Snippet: Drugs and inhibitors used were: cerivastatin (SML0005; Sigma), lovastatin (1530; Tocris), fluvastatin (344075; Calbiochem/EMD Chemicals), simvastatin (567021; Calbiochem/EMD Chemicals), mevastatin (26538076; Sigma), atorvastatin (PZ0001; Sigma), pravastatin (P4498; Sigma), pitavastatin (s1759; Selleckchem), fasudil (F-4660; LC Laboratories), zoledronate (L0223; Sigma), clodronate (D4434; Sigma); thiram (45689; Sigma), pyrithione zinc (H6377; Sigma), BAY11-7082 (196870; EMD Millipore), patulin (P1639; Sigma), mitoxantrone dihydrochloride (M6545; Sigma), zaragozic acid (17452; Cayman Chemical Company), GGTI-298 (G5169; Sigma), GGTI-286 (SML1186; Sigma), FTI-277 (F9803; Sigma), RKI-1447, GGTI-2417, and FTI-2153 (S.M.S.).

    Techniques: Expressing, Mouse Assay, In Situ Hybridization

    Dose–response curves for clodronate and for the N -biphosphonate zoledronate in combination with lovastatin, fluvastatin, or pitavastatin. ( A ) Dose–response curves for the nonnitrogenous bisphosphonate clodronic acid (clodronate) at serial

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Combined HMG-COA reductase and prenylation inhibition in treatment of CCM

    doi: 10.1073/pnas.1702942114

    Figure Lengend Snippet: Dose–response curves for clodronate and for the N -biphosphonate zoledronate in combination with lovastatin, fluvastatin, or pitavastatin. ( A ) Dose–response curves for the nonnitrogenous bisphosphonate clodronic acid (clodronate) at serial

    Article Snippet: Drugs and inhibitors used were: cerivastatin (SML0005; Sigma), lovastatin (1530; Tocris), fluvastatin (344075; Calbiochem/EMD Chemicals), simvastatin (567021; Calbiochem/EMD Chemicals), mevastatin (26538076; Sigma), atorvastatin (PZ0001; Sigma), pravastatin (P4498; Sigma), pitavastatin (s1759; Selleckchem), fasudil (F-4660; LC Laboratories), zoledronate (L0223; Sigma), clodronate (D4434; Sigma); thiram (45689; Sigma), pyrithione zinc (H6377; Sigma), BAY11-7082 (196870; EMD Millipore), patulin (P1639; Sigma), mitoxantrone dihydrochloride (M6545; Sigma), zaragozic acid (17452; Cayman Chemical Company), GGTI-298 (G5169; Sigma), GGTI-286 (SML1186; Sigma), FTI-277 (F9803; Sigma), RKI-1447, GGTI-2417, and FTI-2153 (S.M.S.).

    Techniques:

    Combined treatment with fluvastatin and zoledronate reduces several cellular phenotypes of Ccm3 −/− primary astrocytes. ( A and B ) Collective migration of wild-type and Ccm3 −/− astrocytes on grooved substrata. ( A ) Expansion

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Combined HMG-COA reductase and prenylation inhibition in treatment of CCM

    doi: 10.1073/pnas.1702942114

    Figure Lengend Snippet: Combined treatment with fluvastatin and zoledronate reduces several cellular phenotypes of Ccm3 −/− primary astrocytes. ( A and B ) Collective migration of wild-type and Ccm3 −/− astrocytes on grooved substrata. ( A ) Expansion

    Article Snippet: Drugs and inhibitors used were: cerivastatin (SML0005; Sigma), lovastatin (1530; Tocris), fluvastatin (344075; Calbiochem/EMD Chemicals), simvastatin (567021; Calbiochem/EMD Chemicals), mevastatin (26538076; Sigma), atorvastatin (PZ0001; Sigma), pravastatin (P4498; Sigma), pitavastatin (s1759; Selleckchem), fasudil (F-4660; LC Laboratories), zoledronate (L0223; Sigma), clodronate (D4434; Sigma); thiram (45689; Sigma), pyrithione zinc (H6377; Sigma), BAY11-7082 (196870; EMD Millipore), patulin (P1639; Sigma), mitoxantrone dihydrochloride (M6545; Sigma), zaragozic acid (17452; Cayman Chemical Company), GGTI-298 (G5169; Sigma), GGTI-286 (SML1186; Sigma), FTI-277 (F9803; Sigma), RKI-1447, GGTI-2417, and FTI-2153 (S.M.S.).

    Techniques: Migration

    Fluvastatin and zoledronate treatment reverses the effects of CCM3 knockdown in Drosophila . ( A – L′ ) Knockdown of ccm3 , the single ortholog of Ccm3 in Drosophila . ( A , B , E , and F ) Expression of ccm3-IR with Repo-Gal4 results in increased

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Combined HMG-COA reductase and prenylation inhibition in treatment of CCM

    doi: 10.1073/pnas.1702942114

    Figure Lengend Snippet: Fluvastatin and zoledronate treatment reverses the effects of CCM3 knockdown in Drosophila . ( A – L′ ) Knockdown of ccm3 , the single ortholog of Ccm3 in Drosophila . ( A , B , E , and F ) Expression of ccm3-IR with Repo-Gal4 results in increased

    Article Snippet: Drugs and inhibitors used were: cerivastatin (SML0005; Sigma), lovastatin (1530; Tocris), fluvastatin (344075; Calbiochem/EMD Chemicals), simvastatin (567021; Calbiochem/EMD Chemicals), mevastatin (26538076; Sigma), atorvastatin (PZ0001; Sigma), pravastatin (P4498; Sigma), pitavastatin (s1759; Selleckchem), fasudil (F-4660; LC Laboratories), zoledronate (L0223; Sigma), clodronate (D4434; Sigma); thiram (45689; Sigma), pyrithione zinc (H6377; Sigma), BAY11-7082 (196870; EMD Millipore), patulin (P1639; Sigma), mitoxantrone dihydrochloride (M6545; Sigma), zaragozic acid (17452; Cayman Chemical Company), GGTI-298 (G5169; Sigma), GGTI-286 (SML1186; Sigma), FTI-277 (F9803; Sigma), RKI-1447, GGTI-2417, and FTI-2153 (S.M.S.).

    Techniques: Expressing

    Effects of various mevalonate pathway inhibitors on the action of fluvastatin. ( A – X ). Dose–response curves for various inhibitors of the mevalonate pathway. ( A – C ) Zaragozic acid (squalene synthase inhibitor). ( D – L ) GGTIs:

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Combined HMG-COA reductase and prenylation inhibition in treatment of CCM

    doi: 10.1073/pnas.1702942114

    Figure Lengend Snippet: Effects of various mevalonate pathway inhibitors on the action of fluvastatin. ( A – X ). Dose–response curves for various inhibitors of the mevalonate pathway. ( A – C ) Zaragozic acid (squalene synthase inhibitor). ( D – L ) GGTIs:

    Article Snippet: Drugs and inhibitors used were: cerivastatin (SML0005; Sigma), lovastatin (1530; Tocris), fluvastatin (344075; Calbiochem/EMD Chemicals), simvastatin (567021; Calbiochem/EMD Chemicals), mevastatin (26538076; Sigma), atorvastatin (PZ0001; Sigma), pravastatin (P4498; Sigma), pitavastatin (s1759; Selleckchem), fasudil (F-4660; LC Laboratories), zoledronate (L0223; Sigma), clodronate (D4434; Sigma); thiram (45689; Sigma), pyrithione zinc (H6377; Sigma), BAY11-7082 (196870; EMD Millipore), patulin (P1639; Sigma), mitoxantrone dihydrochloride (M6545; Sigma), zaragozic acid (17452; Cayman Chemical Company), GGTI-298 (G5169; Sigma), GGTI-286 (SML1186; Sigma), FTI-277 (F9803; Sigma), RKI-1447, GGTI-2417, and FTI-2153 (S.M.S.).

    Techniques:

    The fluvastatin and zoledronate combination reverses aberrant proliferation of Ccm3 −/− astrocytes. ( A ) Flowchart of the primary screening, hit-pick, and dose–response experiments. ( B ) Percent (%) effect of statins on proliferation

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Combined HMG-COA reductase and prenylation inhibition in treatment of CCM

    doi: 10.1073/pnas.1702942114

    Figure Lengend Snippet: The fluvastatin and zoledronate combination reverses aberrant proliferation of Ccm3 −/− astrocytes. ( A ) Flowchart of the primary screening, hit-pick, and dose–response experiments. ( B ) Percent (%) effect of statins on proliferation

    Article Snippet: Drugs and inhibitors used were: cerivastatin (SML0005; Sigma), lovastatin (1530; Tocris), fluvastatin (344075; Calbiochem/EMD Chemicals), simvastatin (567021; Calbiochem/EMD Chemicals), mevastatin (26538076; Sigma), atorvastatin (PZ0001; Sigma), pravastatin (P4498; Sigma), pitavastatin (s1759; Selleckchem), fasudil (F-4660; LC Laboratories), zoledronate (L0223; Sigma), clodronate (D4434; Sigma); thiram (45689; Sigma), pyrithione zinc (H6377; Sigma), BAY11-7082 (196870; EMD Millipore), patulin (P1639; Sigma), mitoxantrone dihydrochloride (M6545; Sigma), zaragozic acid (17452; Cayman Chemical Company), GGTI-298 (G5169; Sigma), GGTI-286 (SML1186; Sigma), FTI-277 (F9803; Sigma), RKI-1447, GGTI-2417, and FTI-2153 (S.M.S.).

    Techniques:

    Combined treatment with fluvastatin and zoledronate reverses outcomes of chronic astrocytic CCM3 loss in vivo. ( A – F′ ) The drugs reverse astrocyte hyperproliferation in hGfap/Ccm3 cKO brain. Representative images of coronal sections from

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Combined HMG-COA reductase and prenylation inhibition in treatment of CCM

    doi: 10.1073/pnas.1702942114

    Figure Lengend Snippet: Combined treatment with fluvastatin and zoledronate reverses outcomes of chronic astrocytic CCM3 loss in vivo. ( A – F′ ) The drugs reverse astrocyte hyperproliferation in hGfap/Ccm3 cKO brain. Representative images of coronal sections from

    Article Snippet: Drugs and inhibitors used were: cerivastatin (SML0005; Sigma), lovastatin (1530; Tocris), fluvastatin (344075; Calbiochem/EMD Chemicals), simvastatin (567021; Calbiochem/EMD Chemicals), mevastatin (26538076; Sigma), atorvastatin (PZ0001; Sigma), pravastatin (P4498; Sigma), pitavastatin (s1759; Selleckchem), fasudil (F-4660; LC Laboratories), zoledronate (L0223; Sigma), clodronate (D4434; Sigma); thiram (45689; Sigma), pyrithione zinc (H6377; Sigma), BAY11-7082 (196870; EMD Millipore), patulin (P1639; Sigma), mitoxantrone dihydrochloride (M6545; Sigma), zaragozic acid (17452; Cayman Chemical Company), GGTI-298 (G5169; Sigma), GGTI-286 (SML1186; Sigma), FTI-277 (F9803; Sigma), RKI-1447, GGTI-2417, and FTI-2153 (S.M.S.).

    Techniques: In Vivo

    Combined treatment with fluvastatin and zoledronate reverses outcomes of acute endothelial CCM3 loss in vivo. ( A – U ) The drugs decrease lesion burden ( A – F′ and G–T ) and reverse retinal vascular defects ( A′′

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Combined HMG-COA reductase and prenylation inhibition in treatment of CCM

    doi: 10.1073/pnas.1702942114

    Figure Lengend Snippet: Combined treatment with fluvastatin and zoledronate reverses outcomes of acute endothelial CCM3 loss in vivo. ( A – U ) The drugs decrease lesion burden ( A – F′ and G–T ) and reverse retinal vascular defects ( A′′

    Article Snippet: Drugs and inhibitors used were: cerivastatin (SML0005; Sigma), lovastatin (1530; Tocris), fluvastatin (344075; Calbiochem/EMD Chemicals), simvastatin (567021; Calbiochem/EMD Chemicals), mevastatin (26538076; Sigma), atorvastatin (PZ0001; Sigma), pravastatin (P4498; Sigma), pitavastatin (s1759; Selleckchem), fasudil (F-4660; LC Laboratories), zoledronate (L0223; Sigma), clodronate (D4434; Sigma); thiram (45689; Sigma), pyrithione zinc (H6377; Sigma), BAY11-7082 (196870; EMD Millipore), patulin (P1639; Sigma), mitoxantrone dihydrochloride (M6545; Sigma), zaragozic acid (17452; Cayman Chemical Company), GGTI-298 (G5169; Sigma), GGTI-286 (SML1186; Sigma), FTI-277 (F9803; Sigma), RKI-1447, GGTI-2417, and FTI-2153 (S.M.S.).

    Techniques: In Vivo

    Combined treatment with fluvastatin and zoledronate suppresses the increased migration of Ccm3 −/− astrocytes. ( A – L ) Classical scratch assay. Representative images of astrocytic cell monolayers from wild-type (wt) ( A and B ) and

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Combined HMG-COA reductase and prenylation inhibition in treatment of CCM

    doi: 10.1073/pnas.1702942114

    Figure Lengend Snippet: Combined treatment with fluvastatin and zoledronate suppresses the increased migration of Ccm3 −/− astrocytes. ( A – L ) Classical scratch assay. Representative images of astrocytic cell monolayers from wild-type (wt) ( A and B ) and

    Article Snippet: Drugs and inhibitors used were: cerivastatin (SML0005; Sigma), lovastatin (1530; Tocris), fluvastatin (344075; Calbiochem/EMD Chemicals), simvastatin (567021; Calbiochem/EMD Chemicals), mevastatin (26538076; Sigma), atorvastatin (PZ0001; Sigma), pravastatin (P4498; Sigma), pitavastatin (s1759; Selleckchem), fasudil (F-4660; LC Laboratories), zoledronate (L0223; Sigma), clodronate (D4434; Sigma); thiram (45689; Sigma), pyrithione zinc (H6377; Sigma), BAY11-7082 (196870; EMD Millipore), patulin (P1639; Sigma), mitoxantrone dihydrochloride (M6545; Sigma), zaragozic acid (17452; Cayman Chemical Company), GGTI-298 (G5169; Sigma), GGTI-286 (SML1186; Sigma), FTI-277 (F9803; Sigma), RKI-1447, GGTI-2417, and FTI-2153 (S.M.S.).

    Techniques: Migration, Wound Healing Assay

    Mechanistic effects of fluvastatin and zoledronate in primary astrocytes. ( A ) In Ccm3 −/− astrocytes, RhoA preferentially accumulates in the membrane fraction indicating increased activation; combined treatment results in RhoA enrichment

    Journal: Proceedings of the National Academy of Sciences of the United States of America

    Article Title: Combined HMG-COA reductase and prenylation inhibition in treatment of CCM

    doi: 10.1073/pnas.1702942114

    Figure Lengend Snippet: Mechanistic effects of fluvastatin and zoledronate in primary astrocytes. ( A ) In Ccm3 −/− astrocytes, RhoA preferentially accumulates in the membrane fraction indicating increased activation; combined treatment results in RhoA enrichment

    Article Snippet: Drugs and inhibitors used were: cerivastatin (SML0005; Sigma), lovastatin (1530; Tocris), fluvastatin (344075; Calbiochem/EMD Chemicals), simvastatin (567021; Calbiochem/EMD Chemicals), mevastatin (26538076; Sigma), atorvastatin (PZ0001; Sigma), pravastatin (P4498; Sigma), pitavastatin (s1759; Selleckchem), fasudil (F-4660; LC Laboratories), zoledronate (L0223; Sigma), clodronate (D4434; Sigma); thiram (45689; Sigma), pyrithione zinc (H6377; Sigma), BAY11-7082 (196870; EMD Millipore), patulin (P1639; Sigma), mitoxantrone dihydrochloride (M6545; Sigma), zaragozic acid (17452; Cayman Chemical Company), GGTI-298 (G5169; Sigma), GGTI-286 (SML1186; Sigma), FTI-277 (F9803; Sigma), RKI-1447, GGTI-2417, and FTI-2153 (S.M.S.).

    Techniques: Activation Assay