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The expression level and intracellular distribution of MED19 had no difference between normal cells/tissues and CRC cells/tissues. (A) The expression and distribution of MED19 protein in <t>NCM460</t> cells and SW480 cells. (B) The expression and distribution of MED19 protein in normal colorectal tissues, adjacent colorectal cancer tissues, and colorectal cancer tumor tissues. (C) KCC07 did not affect the expression and distribution of MED19 in SW480 cells. n = 3, ns indicates not significant, *indicates p < 0.05, **indicates p < 0.01, and scale bar = 100 µm.
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The expression level and intracellular distribution of MED19 had no difference between normal cells/tissues and CRC cells/tissues. (A) The expression and distribution of MED19 protein in <t>NCM460</t> cells and SW480 cells. (B) The expression and distribution of MED19 protein in normal colorectal tissues, adjacent colorectal cancer tissues, and colorectal cancer tumor tissues. (C) KCC07 did not affect the expression and distribution of MED19 in SW480 cells. n = 3, ns indicates not significant, *indicates p < 0.05, **indicates p < 0.01, and scale bar = 100 µm.
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The expression level and intracellular distribution of MED19 had no difference between normal cells/tissues and CRC cells/tissues. (A) The expression and distribution of MED19 protein in NCM460 cells and SW480 cells. (B) The expression and distribution of MED19 protein in normal colorectal tissues, adjacent colorectal cancer tissues, and colorectal cancer tumor tissues. (C) KCC07 did not affect the expression and distribution of MED19 in SW480 cells. n = 3, ns indicates not significant, *indicates p < 0.05, **indicates p < 0.01, and scale bar = 100 µm.

Journal: Cancer Biology & Therapy

Article Title: MBD2 suppresses SFRP1 expression and promotes colorectal cancer development by blocking MED19 binding to its methylated promoter

doi: 10.1080/15384047.2026.2667568

Figure Lengend Snippet: The expression level and intracellular distribution of MED19 had no difference between normal cells/tissues and CRC cells/tissues. (A) The expression and distribution of MED19 protein in NCM460 cells and SW480 cells. (B) The expression and distribution of MED19 protein in normal colorectal tissues, adjacent colorectal cancer tissues, and colorectal cancer tumor tissues. (C) KCC07 did not affect the expression and distribution of MED19 in SW480 cells. n = 3, ns indicates not significant, *indicates p < 0.05, **indicates p < 0.01, and scale bar = 100 µm.

Article Snippet: Normal colon mucosa cell line NCM460 (ATCC, CRL-1642 TM ) and the human colorectal cancer cell lines HCT116 (ATCC, CCL-247 TM ) and SW480 (ATCC, CCL-228 TM ) were purchased from iCell, and all had STR identification reports.

Techniques: Expressing