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mp38 cell line stocks  (ATCC)


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    Structured Review

    ATCC mp38 cell line stocks
    (A) Viability of the three UM cell lines following treatment with 932 epigenetic modulators at a concentration of 1 μM (n = 2). Hit cut-offs (dashed lines) were determined as the mean of the negative controls minus three standard deviations. (B) Radar plot showing the average percentage of cell death for the three cell lines treated with 932 compounds. (C) Pie charts of the molecular activities of all screened compounds (left) and the hits identified (right). (D) Dose-response experiments for the identified compounds (10 concentrations, n = 4 per concentration per cell line). (E) LogIC 50 values of the top-hit compounds for each cell line. Error bars represent 95% confidence interval. (F) LogIC 50 of BAP1 mutant cell lines (MP46 and <t>MP38)</t> plotted on the X-axis against the LogIC 50 of the BAP1 WT cell line (MP41) on the Y-axis.
    Mp38 Cell Line Stocks, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 32 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mp38 cell line stocks/product/ATCC
    Average 93 stars, based on 32 article reviews
    mp38 cell line stocks - by Bioz Stars, 2026-02
    93/100 stars

    Images

    1) Product Images from "Identification of targetable epigenetic vulnerabilities in uveal melanoma"

    Article Title: Identification of targetable epigenetic vulnerabilities in uveal melanoma

    Journal: bioRxiv

    doi: 10.1101/2024.10.11.617464

    (A) Viability of the three UM cell lines following treatment with 932 epigenetic modulators at a concentration of 1 μM (n = 2). Hit cut-offs (dashed lines) were determined as the mean of the negative controls minus three standard deviations. (B) Radar plot showing the average percentage of cell death for the three cell lines treated with 932 compounds. (C) Pie charts of the molecular activities of all screened compounds (left) and the hits identified (right). (D) Dose-response experiments for the identified compounds (10 concentrations, n = 4 per concentration per cell line). (E) LogIC 50 values of the top-hit compounds for each cell line. Error bars represent 95% confidence interval. (F) LogIC 50 of BAP1 mutant cell lines (MP46 and MP38) plotted on the X-axis against the LogIC 50 of the BAP1 WT cell line (MP41) on the Y-axis.
    Figure Legend Snippet: (A) Viability of the three UM cell lines following treatment with 932 epigenetic modulators at a concentration of 1 μM (n = 2). Hit cut-offs (dashed lines) were determined as the mean of the negative controls minus three standard deviations. (B) Radar plot showing the average percentage of cell death for the three cell lines treated with 932 compounds. (C) Pie charts of the molecular activities of all screened compounds (left) and the hits identified (right). (D) Dose-response experiments for the identified compounds (10 concentrations, n = 4 per concentration per cell line). (E) LogIC 50 values of the top-hit compounds for each cell line. Error bars represent 95% confidence interval. (F) LogIC 50 of BAP1 mutant cell lines (MP46 and MP38) plotted on the X-axis against the LogIC 50 of the BAP1 WT cell line (MP41) on the Y-axis.

    Techniques Used: Concentration Assay, Mutagenesis

    (A) Concentration-response curves of MP41 and MP38 cells treated with the PARP inhibitor talazoparib. (B) Concentration-response curves of MP41 and MP38 cells treated with HDAC3 and HDAC8 inhibitors. N = 4 for each concentration.
    Figure Legend Snippet: (A) Concentration-response curves of MP41 and MP38 cells treated with the PARP inhibitor talazoparib. (B) Concentration-response curves of MP41 and MP38 cells treated with HDAC3 and HDAC8 inhibitors. N = 4 for each concentration.

    Techniques Used: Concentration Assay



    Similar Products

    mp38 cell line stocks  (ATCC)
    93
    ATCC mp38 cell line stocks
    (A) Viability of the three UM cell lines following treatment with 932 epigenetic modulators at a concentration of 1 μM (n = 2). Hit cut-offs (dashed lines) were determined as the mean of the negative controls minus three standard deviations. (B) Radar plot showing the average percentage of cell death for the three cell lines treated with 932 compounds. (C) Pie charts of the molecular activities of all screened compounds (left) and the hits identified (right). (D) Dose-response experiments for the identified compounds (10 concentrations, n = 4 per concentration per cell line). (E) LogIC 50 values of the top-hit compounds for each cell line. Error bars represent 95% confidence interval. (F) LogIC 50 of BAP1 mutant cell lines (MP46 and <t>MP38)</t> plotted on the X-axis against the LogIC 50 of the BAP1 WT cell line (MP41) on the Y-axis.
    Mp38 Cell Line Stocks, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mp38 cell line stocks/product/ATCC
    Average 93 stars, based on 1 article reviews
    mp38 cell line stocks - by Bioz Stars, 2026-02
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    (A) Viability of the three UM cell lines following treatment with 932 epigenetic modulators at a concentration of 1 μM (n = 2). Hit cut-offs (dashed lines) were determined as the mean of the negative controls minus three standard deviations. (B) Radar plot showing the average percentage of cell death for the three cell lines treated with 932 compounds. (C) Pie charts of the molecular activities of all screened compounds (left) and the hits identified (right). (D) Dose-response experiments for the identified compounds (10 concentrations, n = 4 per concentration per cell line). (E) LogIC 50 values of the top-hit compounds for each cell line. Error bars represent 95% confidence interval. (F) LogIC 50 of BAP1 mutant cell lines (MP46 and MP38) plotted on the X-axis against the LogIC 50 of the BAP1 WT cell line (MP41) on the Y-axis.

    Journal: bioRxiv

    Article Title: Identification of targetable epigenetic vulnerabilities in uveal melanoma

    doi: 10.1101/2024.10.11.617464

    Figure Lengend Snippet: (A) Viability of the three UM cell lines following treatment with 932 epigenetic modulators at a concentration of 1 μM (n = 2). Hit cut-offs (dashed lines) were determined as the mean of the negative controls minus three standard deviations. (B) Radar plot showing the average percentage of cell death for the three cell lines treated with 932 compounds. (C) Pie charts of the molecular activities of all screened compounds (left) and the hits identified (right). (D) Dose-response experiments for the identified compounds (10 concentrations, n = 4 per concentration per cell line). (E) LogIC 50 values of the top-hit compounds for each cell line. Error bars represent 95% confidence interval. (F) LogIC 50 of BAP1 mutant cell lines (MP46 and MP38) plotted on the X-axis against the LogIC 50 of the BAP1 WT cell line (MP41) on the Y-axis.

    Article Snippet: UM (MP41, MP46, and MP38) cell line stocks were obtained from the American Type Tissue Collection (ATCC).

    Techniques: Concentration Assay, Mutagenesis

    (A) Concentration-response curves of MP41 and MP38 cells treated with the PARP inhibitor talazoparib. (B) Concentration-response curves of MP41 and MP38 cells treated with HDAC3 and HDAC8 inhibitors. N = 4 for each concentration.

    Journal: bioRxiv

    Article Title: Identification of targetable epigenetic vulnerabilities in uveal melanoma

    doi: 10.1101/2024.10.11.617464

    Figure Lengend Snippet: (A) Concentration-response curves of MP41 and MP38 cells treated with the PARP inhibitor talazoparib. (B) Concentration-response curves of MP41 and MP38 cells treated with HDAC3 and HDAC8 inhibitors. N = 4 for each concentration.

    Article Snippet: UM (MP41, MP46, and MP38) cell line stocks were obtained from the American Type Tissue Collection (ATCC).

    Techniques: Concentration Assay