mp 41 (Thermo Fisher)
Thermo Fisher is a verified supplier
Thermo Fisher manufactures this product
Structured Review
Mp 41, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mp 41/product/Thermo Fisher
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
Images
1) Product Images from "The deacylase SIRT5 supports melanoma viability by regulating chromatin dynamics"
Article Title: The deacylase SIRT5 supports melanoma viability by regulating chromatin dynamics
Journal: bioRxiv
doi: 10.1101/2020.09.07.286526
Figure Legend Snippet: A. Immunoblot analysis demonstrating induction of caspase 3 cleavage 72 and 96 hrs. post-transduction with shRNAs targeting SIRT5 (KD1 or KD2) in A2058 and SK-MEL-2 cell lines. B . Viability of MP-41, A2058 or YUMM5.2 cells infected with control (C) or one of five SIRT5 shRNAs (KD1-KD5) against human SIRT5 (top and middle panels) or mouse Sirt5 (bottom panel). Average results (n=6/timepoint) are graphed. Error bars represent standard deviation. Right panels: immunoblot analysis demonstrating loss of SIRT5 and induction of caspase 3 cleavage following SIRT5 KD. C. Flow cytometric analysis of A2058 cells stained with Annexin V and propidium iodide (PI), as indicated, showing an increased fraction of Annexin V-positive cells 96 hrs. after SIRT5 KD. D. Average of n=3 technical replicates is plotted. Error bars represent (SD). Significance calculated using unpaired Student’s t-test. Increased Annexin V + staining is observed in both the PI-positive and PI-negative populations.
Techniques Used: Western Blot, Transduction, Infection, Standard Deviation, Staining