Structured Review

Illumina Inc miseq reagent kit
CAP206-CH12 lineage is detected throughout infection. (A) Time-points at which longitudinal antibody next-generation <t>sequencing</t> <t>(Illumina-MiSeq)</t> were conducted and CAP206-CH12.2 and CAP206-CH12 mAbs were isolated. ID 50 plasma neutralization titres of C1C, indicative of an MPER response, are shown in grey scale. (B) Percentage of heavy and light chain somatic hypermutation (SHM) obtained from clonally related sequences from each time-point, compared to their germline IGHV1-69 and IGKV3-20 genes. The grey bars at each time point represent the average percentage SHM. Each dot represents a single heavy or light chain clonally related sequence identified by time-point. The total number of sequences per time-point are given on the x-axis. The levels of SHM for the UCA and CAP206-CH12 are shown as green dots on the graph.
Miseq Reagent Kit, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 86/100, based on 40 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/miseq reagent kit/product/Illumina Inc
Average 86 stars, based on 40 article reviews
Price from $9.99 to $1999.99
miseq reagent kit - by Bioz Stars, 2022-11
86/100 stars

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1) Product Images from "Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies"

Article Title: Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies

Journal: PLoS Pathogens

doi: 10.1371/journal.ppat.1010450

CAP206-CH12 lineage is detected throughout infection. (A) Time-points at which longitudinal antibody next-generation sequencing (Illumina-MiSeq) were conducted and CAP206-CH12.2 and CAP206-CH12 mAbs were isolated. ID 50 plasma neutralization titres of C1C, indicative of an MPER response, are shown in grey scale. (B) Percentage of heavy and light chain somatic hypermutation (SHM) obtained from clonally related sequences from each time-point, compared to their germline IGHV1-69 and IGKV3-20 genes. The grey bars at each time point represent the average percentage SHM. Each dot represents a single heavy or light chain clonally related sequence identified by time-point. The total number of sequences per time-point are given on the x-axis. The levels of SHM for the UCA and CAP206-CH12 are shown as green dots on the graph.
Figure Legend Snippet: CAP206-CH12 lineage is detected throughout infection. (A) Time-points at which longitudinal antibody next-generation sequencing (Illumina-MiSeq) were conducted and CAP206-CH12.2 and CAP206-CH12 mAbs were isolated. ID 50 plasma neutralization titres of C1C, indicative of an MPER response, are shown in grey scale. (B) Percentage of heavy and light chain somatic hypermutation (SHM) obtained from clonally related sequences from each time-point, compared to their germline IGHV1-69 and IGKV3-20 genes. The grey bars at each time point represent the average percentage SHM. Each dot represents a single heavy or light chain clonally related sequence identified by time-point. The total number of sequences per time-point are given on the x-axis. The levels of SHM for the UCA and CAP206-CH12 are shown as green dots on the graph.

Techniques Used: Infection, Next-Generation Sequencing, Isolation, Neutralization, Sequencing

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