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Trinity Biotech mab ift immune complexes
Administration of <t>mAb-</t> <t>iFt</t> immune complexes reverses the anti-inflammatory properties of LVS in mouse PECs ex vivo . C57BL/6 mice were immunized i.n. with PBS, i Ft (2x10 7 CFUs), or mAb- iFt , boosted on day 21 and challenged on day 35 with 10,000 CFUs of Ft LVS. After 48 hours post—LVS challenge, the PECs of immunized mice were harvested and cultured in the presence or absence of Ft . LVS at 1:10 and 1:100 MOI for 24 hrs. The cytokine production was measured as previously described. Results are representative of three independent experiments. (*) P-value
Mab Ift Immune Complexes, supplied by Trinity Biotech, used in various techniques. Bioz Stars score: 88/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mab ift immune complexes/product/Trinity Biotech
Average 88 stars, based on 2 article reviews
Price from $9.99 to $1999.99
mab ift immune complexes - by Bioz Stars, 2020-07
88/100 stars

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Images

1) Product Images from "Targeting of a Fixed Bacterial Immunogen to Fc Receptors Reverses the Anti-Inflammatory Properties of the Gram-Negative Bacterium, Francisella tularensis, during the Early Stages of Infection"

Article Title: Targeting of a Fixed Bacterial Immunogen to Fc Receptors Reverses the Anti-Inflammatory Properties of the Gram-Negative Bacterium, Francisella tularensis, during the Early Stages of Infection

Journal: PLoS ONE

doi: 10.1371/journal.pone.0129981

Administration of mAb- iFt immune complexes reverses the anti-inflammatory properties of LVS in mouse PECs ex vivo . C57BL/6 mice were immunized i.n. with PBS, i Ft (2x10 7 CFUs), or mAb- iFt , boosted on day 21 and challenged on day 35 with 10,000 CFUs of Ft LVS. After 48 hours post—LVS challenge, the PECs of immunized mice were harvested and cultured in the presence or absence of Ft . LVS at 1:10 and 1:100 MOI for 24 hrs. The cytokine production was measured as previously described. Results are representative of three independent experiments. (*) P-value
Figure Legend Snippet: Administration of mAb- iFt immune complexes reverses the anti-inflammatory properties of LVS in mouse PECs ex vivo . C57BL/6 mice were immunized i.n. with PBS, i Ft (2x10 7 CFUs), or mAb- iFt , boosted on day 21 and challenged on day 35 with 10,000 CFUs of Ft LVS. After 48 hours post—LVS challenge, the PECs of immunized mice were harvested and cultured in the presence or absence of Ft . LVS at 1:10 and 1:100 MOI for 24 hrs. The cytokine production was measured as previously described. Results are representative of three independent experiments. (*) P-value

Techniques Used: Ex Vivo, Mouse Assay, Cell Culture

2) Product Images from "In Vivo Mechanisms Involved in Enhanced Protection Utilizing an Fc Receptor-Targeted Mucosal Vaccine Platform in a Bacterial Vaccine and Challenge Model"

Article Title: In Vivo Mechanisms Involved in Enhanced Protection Utilizing an Fc Receptor-Targeted Mucosal Vaccine Platform in a Bacterial Vaccine and Challenge Model

Journal: Infection and Immunity

doi: 10.1128/IAI.02289-14

Increased frequency of activated CD11c + dendritic cells in the lungs of mice immunized with MAb-iFT immune complexes and challenged with F. tularensis LVS. C57BL/6 mice were immunized i.n. with PBS, iFT (1 × 10 9 CFU), F(ab′) 2 -iFT, or MAb-iFT,
Figure Legend Snippet: Increased frequency of activated CD11c + dendritic cells in the lungs of mice immunized with MAb-iFT immune complexes and challenged with F. tularensis LVS. C57BL/6 mice were immunized i.n. with PBS, iFT (1 × 10 9 CFU), F(ab′) 2 -iFT, or MAb-iFT,

Techniques Used: Mouse Assay

Immunization of mice with MAb-iFT immune complexes increases the number of activated CD11c + lung dendritic cells following F. tularensis LVS challenge. C57BL/6 mice were immunized and challenged as for . On days 2 and 5 after F. tularensis LVS infection,
Figure Legend Snippet: Immunization of mice with MAb-iFT immune complexes increases the number of activated CD11c + lung dendritic cells following F. tularensis LVS challenge. C57BL/6 mice were immunized and challenged as for . On days 2 and 5 after F. tularensis LVS infection,

Techniques Used: Mouse Assay, Infection

Increased generation of IFN-γ-producing effector CD4 + T cells in mice immunized with MAb-iFT ICs compared to that in mice immunized with iFT alone. C57BL/6 were immunized and challenged as described for . On day 2 after F. tularensis LVS
Figure Legend Snippet: Increased generation of IFN-γ-producing effector CD4 + T cells in mice immunized with MAb-iFT ICs compared to that in mice immunized with iFT alone. C57BL/6 were immunized and challenged as described for . On day 2 after F. tularensis LVS

Techniques Used: Mouse Assay

Generation of effector memory CD4 + T cells following targeting of iFT to FcR, during F. tularensis LVS challenge, is IL-12 dependent. C57BL/6 (A) or IL-12-deficient (B) mice were immunized and challenged as described for . C57BL/6 mice were also
Figure Legend Snippet: Generation of effector memory CD4 + T cells following targeting of iFT to FcR, during F. tularensis LVS challenge, is IL-12 dependent. C57BL/6 (A) or IL-12-deficient (B) mice were immunized and challenged as described for . C57BL/6 mice were also

Techniques Used: Mouse Assay

Enhanced generation of effector memory CD4 + T cells in the spleens and lungs of mice immunized with MAb-iFT ICs, following F. tularensis LVS challenge. C57BL/6 mice were immunized with PBS, iFT, MAb-iFT, or F(ab′) 2 -iFT and challenged as described
Figure Legend Snippet: Enhanced generation of effector memory CD4 + T cells in the spleens and lungs of mice immunized with MAb-iFT ICs, following F. tularensis LVS challenge. C57BL/6 mice were immunized with PBS, iFT, MAb-iFT, or F(ab′) 2 -iFT and challenged as described

Techniques Used: Mouse Assay

Immunization of mice with MAb-iFT immune complexes enhances the number of CD11c + cells in the lungs of immunized mice following F. tularensis LVS challenge. C57BL/6 mice were immunized i.n. with PBS, iFT (1 × 10 9 CFU), F(ab′) 2 -iFT, or
Figure Legend Snippet: Immunization of mice with MAb-iFT immune complexes enhances the number of CD11c + cells in the lungs of immunized mice following F. tularensis LVS challenge. C57BL/6 mice were immunized i.n. with PBS, iFT (1 × 10 9 CFU), F(ab′) 2 -iFT, or

Techniques Used: Mouse Assay

Immunization of mice with MAb-iFT immune complexes increases the absolute numbers of effector memory CD4 + T cells during F. tularensis LVS infection, in an IL-12-dependent fashion. Immunization and challenge studies were conducted in C57BL/6 mice (A)
Figure Legend Snippet: Immunization of mice with MAb-iFT immune complexes increases the absolute numbers of effector memory CD4 + T cells during F. tularensis LVS infection, in an IL-12-dependent fashion. Immunization and challenge studies were conducted in C57BL/6 mice (A)

Techniques Used: Mouse Assay, Infection

Targeting of iFT to FcR provides protection against F. tularensis LVS challenge in an IL-12-dependent fashion. C57BL/6 (A) or IL-12-deficient (B) mice were immunized i.n. with PBS, iFT (1 × 10 9 CFU), or MAb-iFT, boosted on day 21, and challenged
Figure Legend Snippet: Targeting of iFT to FcR provides protection against F. tularensis LVS challenge in an IL-12-dependent fashion. C57BL/6 (A) or IL-12-deficient (B) mice were immunized i.n. with PBS, iFT (1 × 10 9 CFU), or MAb-iFT, boosted on day 21, and challenged

Techniques Used: Mouse Assay