igg3  (Nordic-Mubio)

 
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    Name:
    Sheep anti Human IgG1 IgG2 IgG3 IgG4 subclass specific
    Description:
    Sheep Serum anti Human IgG1 IgG2 IgG3 IgG4 subclass specific Host Species Note Sheep Human
    Catalog Number:
    ShAHu/IgG1-4 set
    Price:
    [580.33]
    Host:
    Sheep
    Size:
    4 vials
    Category:
    Antibody
    Antibody Type:
    Secondary antibody
    Source:
    polyclonal
    Reactivity:
    Human
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    Structured Review

    Nordic-Mubio igg3
    Treatment with mercuric chloride augments the production of immunoglobulin G2a <t>(IgG2a)</t> antibodies against mouse collagen type II (CII) by mice with collagen-induced arthritis (CIA). Thirty-four (a) and 62 (b) days after secondary immunization with chicken
    Sheep Serum anti Human IgG1 IgG2 IgG3 IgG4 subclass specific Host Species Note Sheep Human
    https://www.bioz.com/result/igg3/product/Nordic-Mubio
    Average 91 stars, based on 2 article reviews
    Price from $9.99 to $1999.99
    igg3 - by Bioz Stars, 2020-07
    91/100 stars

    Images

    1) Product Images from "Exposure to mercuric chloride during the induction phase and after the onset of collagen-induced arthritis enhances immune/autoimmune responses and exacerbates the disease in DBA/1 mice"

    Article Title: Exposure to mercuric chloride during the induction phase and after the onset of collagen-induced arthritis enhances immune/autoimmune responses and exacerbates the disease in DBA/1 mice

    Journal:

    doi: 10.1111/j.1365-2567.2005.02105.x

    Treatment with mercuric chloride augments the production of immunoglobulin G2a (IgG2a) antibodies against mouse collagen type II (CII) by mice with collagen-induced arthritis (CIA). Thirty-four (a) and 62 (b) days after secondary immunization with chicken
    Figure Legend Snippet: Treatment with mercuric chloride augments the production of immunoglobulin G2a (IgG2a) antibodies against mouse collagen type II (CII) by mice with collagen-induced arthritis (CIA). Thirty-four (a) and 62 (b) days after secondary immunization with chicken

    Techniques Used: Mouse Assay

    The production of immunoglobulin G1 (IgG1) and immunoglobulin G2a (IgG2a) anti-nucleolar antibodies (ANolAs) induced by mercury is maintained during the course of collagen-induced arthritis (CIA). Sixty-two days after secondary immunization with chicken
    Figure Legend Snippet: The production of immunoglobulin G1 (IgG1) and immunoglobulin G2a (IgG2a) anti-nucleolar antibodies (ANolAs) induced by mercury is maintained during the course of collagen-induced arthritis (CIA). Sixty-two days after secondary immunization with chicken

    Techniques Used:

    Treatment with mercuric chloride augments the production of immunoglobulin G2a (IgG2a) antibodies against chicken collagen type II (CII) by mice with collagen-induced arthritis (CIA). Thirty-four (a and b) and 62 (c and d) days after secondary immunization
    Figure Legend Snippet: Treatment with mercuric chloride augments the production of immunoglobulin G2a (IgG2a) antibodies against chicken collagen type II (CII) by mice with collagen-induced arthritis (CIA). Thirty-four (a and b) and 62 (c and d) days after secondary immunization

    Techniques Used: Mouse Assay

    2) Product Images from "The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients"

    Article Title: The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

    Journal: Arthritis Research & Therapy

    doi: 10.1186/s13075-017-1392-z

    The number of anti-CarP antibody isotypes and IgG subclasses differs between RA patients and is level dependent. Anti-carbamylated protein ( anti-CarP ) antibody isotypes and immunoglobulin G ( IgG ) subclasses were measured by ELISA in 373 rheumatoid arthritis ( RA ) patients and 196 healthy controls ( HC ). Pie charts show the percentage of RA patients and HC negative or positive for one, two, or three anti-CarP antibody isotypes ( a ) and negative or positive for one, two, three, or four anti-CarP IgG subclasses ( b ). An increase in level of anti-CarP antibody IgG associates with an increase in the number of anti-CarP antibody isotypes ( c ) and IgG subclasses ( d ) in RA patients. Red lines depict means ( e ). Heat maps show the presence of anti-CarP antibody isotypes and IgG subclasses in RA and HC, ranked according to anti-CarP antibody IgG levels. Green and red mark positive and negative sera, respectively. AU arbitrary units
    Figure Legend Snippet: The number of anti-CarP antibody isotypes and IgG subclasses differs between RA patients and is level dependent. Anti-carbamylated protein ( anti-CarP ) antibody isotypes and immunoglobulin G ( IgG ) subclasses were measured by ELISA in 373 rheumatoid arthritis ( RA ) patients and 196 healthy controls ( HC ). Pie charts show the percentage of RA patients and HC negative or positive for one, two, or three anti-CarP antibody isotypes ( a ) and negative or positive for one, two, three, or four anti-CarP IgG subclasses ( b ). An increase in level of anti-CarP antibody IgG associates with an increase in the number of anti-CarP antibody isotypes ( c ) and IgG subclasses ( d ) in RA patients. Red lines depict means ( e ). Heat maps show the presence of anti-CarP antibody isotypes and IgG subclasses in RA and HC, ranked according to anti-CarP antibody IgG levels. Green and red mark positive and negative sera, respectively. AU arbitrary units

    Techniques Used: Enzyme-linked Immunosorbent Assay

    Anti-CarP IgG1 is associated with more severe radiological progression. The extent and rate of joint destruction was analysed in all rheumatoid arthritis ( RA ) patients or separately for anti-citrullinated protein antibody ( ACPA )-negative and ACPA-positive RA and within the ACPA-negative RA patients also separately for rheumatoid factor (RF) negative and positive. The severity of joint damage is depicted as median Sharp-van der Heijde score ( SHS ) on the y axis and the follow-up years on the x axis for anti-carbamylated protein ( anti-CarP ) antibody immunoglobulin ( Ig )G1-positive and -negative patients in all RA patients analysed ( a ) and for ACPA- and RF-negative RA patients ( b ). β and p values are derived from the analysis model as described in the Methods and Results sections
    Figure Legend Snippet: Anti-CarP IgG1 is associated with more severe radiological progression. The extent and rate of joint destruction was analysed in all rheumatoid arthritis ( RA ) patients or separately for anti-citrullinated protein antibody ( ACPA )-negative and ACPA-positive RA and within the ACPA-negative RA patients also separately for rheumatoid factor (RF) negative and positive. The severity of joint damage is depicted as median Sharp-van der Heijde score ( SHS ) on the y axis and the follow-up years on the x axis for anti-carbamylated protein ( anti-CarP ) antibody immunoglobulin ( Ig )G1-positive and -negative patients in all RA patients analysed ( a ) and for ACPA- and RF-negative RA patients ( b ). β and p values are derived from the analysis model as described in the Methods and Results sections

    Techniques Used: Derivative Assay

    Distribution of anti-CarP and ACPA isotypes and IgG subclasses. a Percentage positivity of anti-citrullinated protein antibody ( ACPA ; black bars ) or anti-carbamylated protein ( anti-CarP ) antibody ( grey bars ) immunoglobulin ( Ig )M, IgA, and IgG subclasses in ACPA and anti-CarP antibody IgG double-positive RA patients ( n = 114). b Percentage single- or double-positive for ACPA ( grey ) and anti-CarP antibody ( light grey ) isotypes and IgG subclasses in IgG double-positive RA patients. Circles are not to scale. Number of anti-CarP antibody and ACPA isotypes ( c ) and IgG subclasses ( d ) in anti-CarP antibody and ACPA IgG double-positive RA patients and at least positive for one IgG subclass ( n = 90)
    Figure Legend Snippet: Distribution of anti-CarP and ACPA isotypes and IgG subclasses. a Percentage positivity of anti-citrullinated protein antibody ( ACPA ; black bars ) or anti-carbamylated protein ( anti-CarP ) antibody ( grey bars ) immunoglobulin ( Ig )M, IgA, and IgG subclasses in ACPA and anti-CarP antibody IgG double-positive RA patients ( n = 114). b Percentage single- or double-positive for ACPA ( grey ) and anti-CarP antibody ( light grey ) isotypes and IgG subclasses in IgG double-positive RA patients. Circles are not to scale. Number of anti-CarP antibody and ACPA isotypes ( c ) and IgG subclasses ( d ) in anti-CarP antibody and ACPA IgG double-positive RA patients and at least positive for one IgG subclass ( n = 90)

    Techniques Used:

    Anti-CarP antibody isotypes and IgG subclasses are present in RA sera. ELISAs were performed to detect anti-carbamylated protein ( anti-CarP ) antibody isotypes ( a ) and immunoglobulin G ( IgG ) subclasses ( b ) in sera of 196 healthy controls ( HC ) and 373 rheumatoid arthritis ( RA ) patients. The mean ( red line ) plus two times the standard deviation in HC was established as the cut-off for the anti-CarP antibody isotypes. The 97 th percentile in HC was used as the cut-off for the IgG subclasses. The dotted line represents the cut-off. The specific anti-CarP reactivity is depicted in arbitrary units ( AU ) per millilitre. The number of samples tested and the percentage positivity is shown below the graphs. c Percentage positivity of anti-CarP antibody isotypes and IgG subclasses in all RA patients ( grey bars , n = 373), anti-citrullinated protein antibody ( ACPA ) IgG-positive RA patients ( dark grey bars , n = 217), ACPA IgG-negative RA patients ( black bars , n = 156), and HC ( light grey bars , n = 196)
    Figure Legend Snippet: Anti-CarP antibody isotypes and IgG subclasses are present in RA sera. ELISAs were performed to detect anti-carbamylated protein ( anti-CarP ) antibody isotypes ( a ) and immunoglobulin G ( IgG ) subclasses ( b ) in sera of 196 healthy controls ( HC ) and 373 rheumatoid arthritis ( RA ) patients. The mean ( red line ) plus two times the standard deviation in HC was established as the cut-off for the anti-CarP antibody isotypes. The 97 th percentile in HC was used as the cut-off for the IgG subclasses. The dotted line represents the cut-off. The specific anti-CarP reactivity is depicted in arbitrary units ( AU ) per millilitre. The number of samples tested and the percentage positivity is shown below the graphs. c Percentage positivity of anti-CarP antibody isotypes and IgG subclasses in all RA patients ( grey bars , n = 373), anti-citrullinated protein antibody ( ACPA ) IgG-positive RA patients ( dark grey bars , n = 217), ACPA IgG-negative RA patients ( black bars , n = 156), and HC ( light grey bars , n = 196)

    Techniques Used: Standard Deviation

    3) Product Images from "Mercury and silver induce B cell activation and anti-nucleolar autoantibody production in outbred mouse stocks: are environmental factors more important than the susceptibility genes in connection with autoimmunity?"

    Article Title: Mercury and silver induce B cell activation and anti-nucleolar autoantibody production in outbred mouse stocks: are environmental factors more important than the susceptibility genes in connection with autoimmunity?

    Journal: Clinical and Experimental Immunology

    doi: 10.1111/j.1365-2249.2008.03801.x

    Induction of anti-nucleolar autoantibodies (ANolA) of IgG1 and IgG2a isotypes in outbred Institute of Cancer Research (ICR), Naval Medical Research Institute (NMRI) and Black Swiss mice treated with silver nitrate (AgNO 3 ). Groups of female ICR (solid and open circles), NMRI (solid and open squares) and Black Swiss (solid and open hexagons) outbred mice were injected repeatedly subcutaneously (s.c.) with AgNO 3 (solid symbols) or NaCl (open symbols) for 4 weeks. At the end of each experiment the mice were bled and killed. The sera were tested for the presence of immunoglobulin (Ig)G1 (a) and IgG2a (b) ANolA by using an indirect immunofluorescence (IIF) method. Each symbol represents a single animal. The mean values ± standard error are presented as thin vertical lines. Values in parentheses represent the proportions of silver-treated animals, which produce ANolA.
    Figure Legend Snippet: Induction of anti-nucleolar autoantibodies (ANolA) of IgG1 and IgG2a isotypes in outbred Institute of Cancer Research (ICR), Naval Medical Research Institute (NMRI) and Black Swiss mice treated with silver nitrate (AgNO 3 ). Groups of female ICR (solid and open circles), NMRI (solid and open squares) and Black Swiss (solid and open hexagons) outbred mice were injected repeatedly subcutaneously (s.c.) with AgNO 3 (solid symbols) or NaCl (open symbols) for 4 weeks. At the end of each experiment the mice were bled and killed. The sera were tested for the presence of immunoglobulin (Ig)G1 (a) and IgG2a (b) ANolA by using an indirect immunofluorescence (IIF) method. Each symbol represents a single animal. The mean values ± standard error are presented as thin vertical lines. Values in parentheses represent the proportions of silver-treated animals, which produce ANolA.

    Techniques Used: Mouse Assay, Injection, Immunofluorescence

    Induction of anti-nucleolar autoantibodies (ANolA) of IgG1 and IgG2a isotypes in outbred Institute of Cancer Research (ICR), Naval Medical Research Institute (NMRI) and Black Swiss mice treated with mercuric chloride (HgCl 2 ). Groups of female ICR (solid and open circles), NMRI (solid and open squares) and Black Swiss (solid and open hexagons) outbred mice were injected repeatedly subcutaneously (s.c.) with HgCl 2 (solid symbols) or NaCl (open symbols) for 4 weeks. At the end of each experiment the mice were bled and killed. The sera were tested for the presence of IgG1 (a) and IgG2a (b) ANolA by using an indirect immunofluorescence (IIF) method. Each symbol represents a single animal. The mean values ± standard error are presented as thin vertical lines. Values in parentheses represent the proportions of mercury-treated animals, which produce ANolA.
    Figure Legend Snippet: Induction of anti-nucleolar autoantibodies (ANolA) of IgG1 and IgG2a isotypes in outbred Institute of Cancer Research (ICR), Naval Medical Research Institute (NMRI) and Black Swiss mice treated with mercuric chloride (HgCl 2 ). Groups of female ICR (solid and open circles), NMRI (solid and open squares) and Black Swiss (solid and open hexagons) outbred mice were injected repeatedly subcutaneously (s.c.) with HgCl 2 (solid symbols) or NaCl (open symbols) for 4 weeks. At the end of each experiment the mice were bled and killed. The sera were tested for the presence of IgG1 (a) and IgG2a (b) ANolA by using an indirect immunofluorescence (IIF) method. Each symbol represents a single animal. The mean values ± standard error are presented as thin vertical lines. Values in parentheses represent the proportions of mercury-treated animals, which produce ANolA.

    Techniques Used: Mouse Assay, Injection, Immunofluorescence

    4) Product Images from "Human immune responses to infective stage larval-specific chitinase of filarial parasite, Onchocerca volvulus, Ov-CHI-1."

    Article Title: Human immune responses to infective stage larval-specific chitinase of filarial parasite, Onchocerca volvulus, Ov-CHI-1.

    Journal: Filaria Journal

    doi: 10.1186/1475-2883-2-6

    Analysis of IgG responses to Ov-CHI-1 plotted against microfilarial skin densities for individual individuals from four endemic regions. Figure 8A : Nigeria, Figure 8B Ecuador, Figure 8C Togo, Figure 8D . Cameroon. The line of linear regression is shown on each graph.
    Figure Legend Snippet: Analysis of IgG responses to Ov-CHI-1 plotted against microfilarial skin densities for individual individuals from four endemic regions. Figure 8A : Nigeria, Figure 8B Ecuador, Figure 8C Togo, Figure 8D . Cameroon. The line of linear regression is shown on each graph.

    Techniques Used:

    Analysis of IgG responses of human onchocerciasis to Ov-CHI-1 categorized by gender and comparison of responses in the sera of infected (INF) and putatively immune (PI) individuals from four endemic foci.
    Figure Legend Snippet: Analysis of IgG responses of human onchocerciasis to Ov-CHI-1 categorized by gender and comparison of responses in the sera of infected (INF) and putatively immune (PI) individuals from four endemic foci.

    Techniques Used: Infection

    Analysis of IgG responses to Ov-CHI-1 with respect to skin nodule number for individual subject from four endemic regions. Figure 9A : Cameroon, Figure 9B : Ecuador, Figure 9C : Nigeria.
    Figure Legend Snippet: Analysis of IgG responses to Ov-CHI-1 with respect to skin nodule number for individual subject from four endemic regions. Figure 9A : Cameroon, Figure 9B : Ecuador, Figure 9C : Nigeria.

    Techniques Used:

    IgG subclass analysis by ELISA on Ov-CHI-1 full-length antigen using 77 selected sera (see text). The whole profile of IgG1-IgG4 responses is shown in Figure 2A . Figure 2B shows the relationship between microfilarial skin density and anti-Ov-CHI-1 IgG3 level in these sera. The relationship of IgG1 with IgG3 is shown in Figure 2C .
    Figure Legend Snippet: IgG subclass analysis by ELISA on Ov-CHI-1 full-length antigen using 77 selected sera (see text). The whole profile of IgG1-IgG4 responses is shown in Figure 2A . Figure 2B shows the relationship between microfilarial skin density and anti-Ov-CHI-1 IgG3 level in these sera. The relationship of IgG1 with IgG3 is shown in Figure 2C .

    Techniques Used: Enzyme-linked Immunosorbent Assay

    ELISA analysis of the IgG response to recombinant Ov-CHI-1 5' or 3' antigen in human onchocerciasis. Figure 4A : Comparison of the response in the sera of infected (INF) and putatively immune (PI) individuals. Figure 4B : The relationship of response to 5' antigen and 3' antigen for individual sera. The line of liner regression is shown for data sets in which there is a statistically significant correlation between responses to the two antigens (determined by Spearman's Rank Correlation Coefficient).
    Figure Legend Snippet: ELISA analysis of the IgG response to recombinant Ov-CHI-1 5' or 3' antigen in human onchocerciasis. Figure 4A : Comparison of the response in the sera of infected (INF) and putatively immune (PI) individuals. Figure 4B : The relationship of response to 5' antigen and 3' antigen for individual sera. The line of liner regression is shown for data sets in which there is a statistically significant correlation between responses to the two antigens (determined by Spearman's Rank Correlation Coefficient).

    Techniques Used: Enzyme-linked Immunosorbent Assay, Recombinant, Infection

    Analysis of IgG responses to Ov-CHI-1 categorized by age for individual individuals from four endemic regions. Figure 6A : Nigeria, Figure 6B : Ecuador, Figure 6C : Togo, Figure 6D : Cameroon.
    Figure Legend Snippet: Analysis of IgG responses to Ov-CHI-1 categorized by age for individual individuals from four endemic regions. Figure 6A : Nigeria, Figure 6B : Ecuador, Figure 6C : Togo, Figure 6D : Cameroon.

    Techniques Used:

    ELISA analysis of the IgG response to recombinant Ov-CHI-1 in human onchocerciasis. Figure 1A , Comparison of the response in sera of endemic individuals from 4 endemic foci with uninfected controls from the United Kingdom. Mean values are indicated by a horizontal line. Figure 1B , Comparison of the response in the sera of infected (INF) and putatively immune (PI) individuals from 4 endemic foci and from uninfected UK controls. Box and whisker plots illustrate the group mean values (horizontal bar), data points falling within the 25th to 75th percentile (boxed) and the range (vertical lines). * P =
    Figure Legend Snippet: ELISA analysis of the IgG response to recombinant Ov-CHI-1 in human onchocerciasis. Figure 1A , Comparison of the response in sera of endemic individuals from 4 endemic foci with uninfected controls from the United Kingdom. Mean values are indicated by a horizontal line. Figure 1B , Comparison of the response in the sera of infected (INF) and putatively immune (PI) individuals from 4 endemic foci and from uninfected UK controls. Box and whisker plots illustrate the group mean values (horizontal bar), data points falling within the 25th to 75th percentile (boxed) and the range (vertical lines). * P =

    Techniques Used: Enzyme-linked Immunosorbent Assay, Recombinant, Infection, Whisker Assay

    5) Product Images from "Mechanism of mercury-induced autoimmunity: both T helper 1- and T helper 2-type responses are involved"

    Article Title: Mechanism of mercury-induced autoimmunity: both T helper 1- and T helper 2-type responses are involved

    Journal: Immunology

    doi: 10.1046/j.1365-2567.1999.00671.x

    Mercury-induced renal IgG deposits of various antibody isotypes in both C57BL/6 wild-type and IL-4-deficient mice
    Figure Legend Snippet: Mercury-induced renal IgG deposits of various antibody isotypes in both C57BL/6 wild-type and IL-4-deficient mice

    Techniques Used: Mouse Assay

    Downregulation of IgG2a and IgG3 but not IgG2b antibody production by anti-IFN-γ antibody treatment in mercury-treated C57BL/6 IL-4-deficient mice. C57BL/6 IL-4-deficient mice (three to four mice per group) were treated with saline or mercury and anti-IFN-γ or control antibodies as described in the Materials and Methods. After 4 weeks, the IgG2b and IgG3 antibody-producing cells in the spleens were measured by PFC (a) and serum IgG2a levels were measured by ELISA (b). Data are shown as the means of PFC/spleen±1 SD or absorbance values±1 SD. * P
    Figure Legend Snippet: Downregulation of IgG2a and IgG3 but not IgG2b antibody production by anti-IFN-γ antibody treatment in mercury-treated C57BL/6 IL-4-deficient mice. C57BL/6 IL-4-deficient mice (three to four mice per group) were treated with saline or mercury and anti-IFN-γ or control antibodies as described in the Materials and Methods. After 4 weeks, the IgG2b and IgG3 antibody-producing cells in the spleens were measured by PFC (a) and serum IgG2a levels were measured by ELISA (b). Data are shown as the means of PFC/spleen±1 SD or absorbance values±1 SD. * P

    Techniques Used: Mouse Assay, Enzyme-linked Immunosorbent Assay

    Mercury induced various antibody production in the spleens of C57BL/6 wild-type and IL-4-deficient mice. Groups of mice were repeatedly injected s.c. with either HgCl 2 or saline. At different times after injections, spleens of three to eight mice were tested for IgM, IgG1, IgG2b and IgG3 antibody-secreting cells. Data are shown as the means of PFC/spleen±1 SD. Significant differences between mercury- and saline-injected mice were calculated by Wilcoxon–Mann–Whitney test, except the data of IL-4-deficient mice on weeks 6 and 8, to which a Student’s t -test was applied because of the small number of mice (two per group) used in saline control groups, * P
    Figure Legend Snippet: Mercury induced various antibody production in the spleens of C57BL/6 wild-type and IL-4-deficient mice. Groups of mice were repeatedly injected s.c. with either HgCl 2 or saline. At different times after injections, spleens of three to eight mice were tested for IgM, IgG1, IgG2b and IgG3 antibody-secreting cells. Data are shown as the means of PFC/spleen±1 SD. Significant differences between mercury- and saline-injected mice were calculated by Wilcoxon–Mann–Whitney test, except the data of IL-4-deficient mice on weeks 6 and 8, to which a Student’s t -test was applied because of the small number of mice (two per group) used in saline control groups, * P

    Techniques Used: Mouse Assay, Injection, MANN-WHITNEY

    Serum antibody levels of different isotypes in mercury-treated C57BL/6 IL-4-deficient mice. Groups of mice were repeatedly injected s.c. with either HgCl 2 (solid symbols) or saline (open symbols). At week 4 (w4) and 6 (w6), pooled sera collected from the blood of three to four experimental mice were measured for serum levels of IgM (a), IgG1 (b), IgG2a (c) IgG2b (d) and IgG3(e) antibodies. In the case of IgE antibody, the serum levels of this antibody (f) were measured at different times: solid circle (day 7, mercury-treated), solid triangle (day 14, mercury-treated), solid square (week 4, mercury-treated) and open square (week 4, saline-treated). Since similar levels of IgE antibodies were found in the saline-treated mice at different times, we showed only the serum IgE levels for week 4 in these mice.
    Figure Legend Snippet: Serum antibody levels of different isotypes in mercury-treated C57BL/6 IL-4-deficient mice. Groups of mice were repeatedly injected s.c. with either HgCl 2 (solid symbols) or saline (open symbols). At week 4 (w4) and 6 (w6), pooled sera collected from the blood of three to four experimental mice were measured for serum levels of IgM (a), IgG1 (b), IgG2a (c) IgG2b (d) and IgG3(e) antibodies. In the case of IgE antibody, the serum levels of this antibody (f) were measured at different times: solid circle (day 7, mercury-treated), solid triangle (day 14, mercury-treated), solid square (week 4, mercury-treated) and open square (week 4, saline-treated). Since similar levels of IgE antibodies were found in the saline-treated mice at different times, we showed only the serum IgE levels for week 4 in these mice.

    Techniques Used: Mouse Assay, Injection

    Serum antibody levels of different isotypes in mercury-treated C57BL/6 wild-type mice. Groups of mice were repeatedly injected s.c. with either HgCl 2 (solid symbols) or saline (open symbols). At week 4 (w4) and 6 (w6), pooled sera collected from the blood of three to four experimental mice were measured for serum levels of IgM (a), IgG1 (b), IgG2a (c) IgG2b (d) and IgG3 (e) antibodies. In the case of IgE antibody, the serum levels of this antibody (f) were measured at different times: solid circle (day 7, mercury treated), solid triangle (day 14, mercury treated), solid square (week 4, mercury treated) and open square (week 4, saline treated). As similar levels of IgE antibodies were found in the saline-treated mice at different times, we showed only the serum IgE levels for week 4 in these mice.
    Figure Legend Snippet: Serum antibody levels of different isotypes in mercury-treated C57BL/6 wild-type mice. Groups of mice were repeatedly injected s.c. with either HgCl 2 (solid symbols) or saline (open symbols). At week 4 (w4) and 6 (w6), pooled sera collected from the blood of three to four experimental mice were measured for serum levels of IgM (a), IgG1 (b), IgG2a (c) IgG2b (d) and IgG3 (e) antibodies. In the case of IgE antibody, the serum levels of this antibody (f) were measured at different times: solid circle (day 7, mercury treated), solid triangle (day 14, mercury treated), solid square (week 4, mercury treated) and open square (week 4, saline treated). As similar levels of IgE antibodies were found in the saline-treated mice at different times, we showed only the serum IgE levels for week 4 in these mice.

    Techniques Used: Mouse Assay, Injection

    6) Product Images from "Analysis of mercury-induced immune activation in nonobese diabetic (NOD) mice"

    Article Title: Analysis of mercury-induced immune activation in nonobese diabetic (NOD) mice

    Journal: Clinical and Experimental Immunology

    doi: 10.1046/j.1365-2249.2001.01580.x

    Mercury induces antibody production of various isotypes in young NOD mice. Groups of young female NOD mice (3–12 mice/group) were repeatedly injected s.c. with mercuric chloride (•). Control mice were either injected with sterile saline or left uninjected (○). At different times after injections, the mice were bled and killed. The spleens were tested for IgM, IgG1, IgG2b and IgG3 antibody secreting cells by using a protein A plaque assay and the sera were tested for IgE by using an ELISA method. Data are shown as the means + 1 s.e. Significant differences between the parameters in mercury- and saline-injected mice were calculated by Wilcoxon–Mann–Whitney test. Tukey's test was used to correct the P -values. * P
    Figure Legend Snippet: Mercury induces antibody production of various isotypes in young NOD mice. Groups of young female NOD mice (3–12 mice/group) were repeatedly injected s.c. with mercuric chloride (•). Control mice were either injected with sterile saline or left uninjected (○). At different times after injections, the mice were bled and killed. The spleens were tested for IgM, IgG1, IgG2b and IgG3 antibody secreting cells by using a protein A plaque assay and the sera were tested for IgE by using an ELISA method. Data are shown as the means + 1 s.e. Significant differences between the parameters in mercury- and saline-injected mice were calculated by Wilcoxon–Mann–Whitney test. Tukey's test was used to correct the P -values. * P

    Techniques Used: Mouse Assay, Injection, Plaque Assay, Enzyme-linked Immunosorbent Assay, MANN-WHITNEY

    7) Product Images from "Bacterial lipopolysaccharide both renders resistant mice susceptible to mercury-induced autoimmunity and exacerbates such autoimmunity in susceptible mice"

    Article Title: Bacterial lipopolysaccharide both renders resistant mice susceptible to mercury-induced autoimmunity and exacerbates such autoimmunity in susceptible mice

    Journal:

    doi: 10.1111/j.1365-2249.2005.02849.x

    Immunofluorescent detection of glomerular deposits of IgG1 in the kidneys of DBA/2 mice administered mercuric chloride in combination with lipopolysaccharide (LPS). The kidneys from the same animals presented in were tested for the presence of
    Figure Legend Snippet: Immunofluorescent detection of glomerular deposits of IgG1 in the kidneys of DBA/2 mice administered mercuric chloride in combination with lipopolysaccharide (LPS). The kidneys from the same animals presented in were tested for the presence of

    Techniques Used: Mouse Assay

    Administration of bacterial lipopolysaccharide (LPS) together with mercuric chloride to DBA/2 mice increases their production of IgG1 antibodies to both exogenous and endogenous antigens. The levels of IgG1 antibodies directed against TNP (a), ssDNA (b),
    Figure Legend Snippet: Administration of bacterial lipopolysaccharide (LPS) together with mercuric chloride to DBA/2 mice increases their production of IgG1 antibodies to both exogenous and endogenous antigens. The levels of IgG1 antibodies directed against TNP (a), ssDNA (b),

    Techniques Used: Mouse Assay

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    Article Title: Humoral and cellular immunogenecity of DNA vaccine based on hepatitis B core gene in rhesus monkeys
    Article Snippet: .. 1:500 diluted sheep anti-human IgG1, IgG2, IgG3 and IgG4 (Nordic Immunological Laboratories, Tilburg, the Netherlands) were used as the second antibody, and 1:5000 diluted HRP labeled rabbit anti-sheep IgG (Jackson Immuno-Research Laboratories Inc, PA, USA) was used as the third antibody. .. The procedures were as follows: ① PBMCs were separated from heparinized monkey blood by Ficoll gradient sedimentation method.

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  • 92
    Nordic-Mubio igg1
    Treatment with mercuric chloride augments the production of immunoglobulin G2a <t>(IgG2a)</t> antibodies against mouse collagen type II (CII) by mice with collagen-induced arthritis (CIA). Thirty-four (a) and 62 (b) days after secondary immunization with chicken
    Igg1, supplied by Nordic-Mubio, used in various techniques. Bioz Stars score: 92/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 92 stars, based on 4 article reviews
    Price from $9.99 to $1999.99
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    Nordic-Mubio goat anti rhesus igg
    Effect of administration of rUre plus LT or placebo plus LT on conversion in specific antiurease serum and saliva <t>IgG</t> and <t>IgA</t> at 1 week after the fourth immunization. The H. pylori + or − designation reflects the status at endoscopy 10 months after the first immunization. ODU, OD units.
    Goat Anti Rhesus Igg, supplied by Nordic-Mubio, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/goat anti rhesus igg/product/Nordic-Mubio
    Average 88 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    goat anti rhesus igg - by Bioz Stars, 2020-07
    88/100 stars
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    Image Search Results


    Treatment with mercuric chloride augments the production of immunoglobulin G2a (IgG2a) antibodies against mouse collagen type II (CII) by mice with collagen-induced arthritis (CIA). Thirty-four (a) and 62 (b) days after secondary immunization with chicken

    Journal:

    Article Title: Exposure to mercuric chloride during the induction phase and after the onset of collagen-induced arthritis enhances immune/autoimmune responses and exacerbates the disease in DBA/1 mice

    doi: 10.1111/j.1365-2567.2005.02105.x

    Figure Lengend Snippet: Treatment with mercuric chloride augments the production of immunoglobulin G2a (IgG2a) antibodies against mouse collagen type II (CII) by mice with collagen-induced arthritis (CIA). Thirty-four (a) and 62 (b) days after secondary immunization with chicken

    Article Snippet: Rabbit anti-mouse IgM, IgG1, IgG3 (Organon Teknika, Durham, NC) and IgG2b (Nordic Immunological Laboratories, Tillburg, the Netherlands) were employed as developing agents.

    Techniques: Mouse Assay

    The production of immunoglobulin G1 (IgG1) and immunoglobulin G2a (IgG2a) anti-nucleolar antibodies (ANolAs) induced by mercury is maintained during the course of collagen-induced arthritis (CIA). Sixty-two days after secondary immunization with chicken

    Journal:

    Article Title: Exposure to mercuric chloride during the induction phase and after the onset of collagen-induced arthritis enhances immune/autoimmune responses and exacerbates the disease in DBA/1 mice

    doi: 10.1111/j.1365-2567.2005.02105.x

    Figure Lengend Snippet: The production of immunoglobulin G1 (IgG1) and immunoglobulin G2a (IgG2a) anti-nucleolar antibodies (ANolAs) induced by mercury is maintained during the course of collagen-induced arthritis (CIA). Sixty-two days after secondary immunization with chicken

    Article Snippet: Rabbit anti-mouse IgM, IgG1, IgG3 (Organon Teknika, Durham, NC) and IgG2b (Nordic Immunological Laboratories, Tillburg, the Netherlands) were employed as developing agents.

    Techniques:

    Treatment with mercuric chloride augments the production of immunoglobulin G2a (IgG2a) antibodies against chicken collagen type II (CII) by mice with collagen-induced arthritis (CIA). Thirty-four (a and b) and 62 (c and d) days after secondary immunization

    Journal:

    Article Title: Exposure to mercuric chloride during the induction phase and after the onset of collagen-induced arthritis enhances immune/autoimmune responses and exacerbates the disease in DBA/1 mice

    doi: 10.1111/j.1365-2567.2005.02105.x

    Figure Lengend Snippet: Treatment with mercuric chloride augments the production of immunoglobulin G2a (IgG2a) antibodies against chicken collagen type II (CII) by mice with collagen-induced arthritis (CIA). Thirty-four (a and b) and 62 (c and d) days after secondary immunization

    Article Snippet: Rabbit anti-mouse IgM, IgG1, IgG3 (Organon Teknika, Durham, NC) and IgG2b (Nordic Immunological Laboratories, Tillburg, the Netherlands) were employed as developing agents.

    Techniques: Mouse Assay

    The number of anti-CarP antibody isotypes and IgG subclasses differs between RA patients and is level dependent. Anti-carbamylated protein ( anti-CarP ) antibody isotypes and immunoglobulin G ( IgG ) subclasses were measured by ELISA in 373 rheumatoid arthritis ( RA ) patients and 196 healthy controls ( HC ). Pie charts show the percentage of RA patients and HC negative or positive for one, two, or three anti-CarP antibody isotypes ( a ) and negative or positive for one, two, three, or four anti-CarP IgG subclasses ( b ). An increase in level of anti-CarP antibody IgG associates with an increase in the number of anti-CarP antibody isotypes ( c ) and IgG subclasses ( d ) in RA patients. Red lines depict means ( e ). Heat maps show the presence of anti-CarP antibody isotypes and IgG subclasses in RA and HC, ranked according to anti-CarP antibody IgG levels. Green and red mark positive and negative sera, respectively. AU arbitrary units

    Journal: Arthritis Research & Therapy

    Article Title: The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

    doi: 10.1186/s13075-017-1392-z

    Figure Lengend Snippet: The number of anti-CarP antibody isotypes and IgG subclasses differs between RA patients and is level dependent. Anti-carbamylated protein ( anti-CarP ) antibody isotypes and immunoglobulin G ( IgG ) subclasses were measured by ELISA in 373 rheumatoid arthritis ( RA ) patients and 196 healthy controls ( HC ). Pie charts show the percentage of RA patients and HC negative or positive for one, two, or three anti-CarP antibody isotypes ( a ) and negative or positive for one, two, three, or four anti-CarP IgG subclasses ( b ). An increase in level of anti-CarP antibody IgG associates with an increase in the number of anti-CarP antibody isotypes ( c ) and IgG subclasses ( d ) in RA patients. Red lines depict means ( e ). Heat maps show the presence of anti-CarP antibody isotypes and IgG subclasses in RA and HC, ranked according to anti-CarP antibody IgG levels. Green and red mark positive and negative sera, respectively. AU arbitrary units

    Article Snippet: Bound human IgG2 or IgG3 was detected using MAH-IgG2 (Nordic MUbio, Clone HP6014) or MAH-IgG3 (Nordic MUbio, Clone HP6080) continued with HRP-conjugated GAM-Ig (DAKO, P0447) and rabbit-anti-goat (RAG)-Ig (DAKO, P0449).

    Techniques: Enzyme-linked Immunosorbent Assay

    Anti-CarP IgG1 is associated with more severe radiological progression. The extent and rate of joint destruction was analysed in all rheumatoid arthritis ( RA ) patients or separately for anti-citrullinated protein antibody ( ACPA )-negative and ACPA-positive RA and within the ACPA-negative RA patients also separately for rheumatoid factor (RF) negative and positive. The severity of joint damage is depicted as median Sharp-van der Heijde score ( SHS ) on the y axis and the follow-up years on the x axis for anti-carbamylated protein ( anti-CarP ) antibody immunoglobulin ( Ig )G1-positive and -negative patients in all RA patients analysed ( a ) and for ACPA- and RF-negative RA patients ( b ). β and p values are derived from the analysis model as described in the Methods and Results sections

    Journal: Arthritis Research & Therapy

    Article Title: The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

    doi: 10.1186/s13075-017-1392-z

    Figure Lengend Snippet: Anti-CarP IgG1 is associated with more severe radiological progression. The extent and rate of joint destruction was analysed in all rheumatoid arthritis ( RA ) patients or separately for anti-citrullinated protein antibody ( ACPA )-negative and ACPA-positive RA and within the ACPA-negative RA patients also separately for rheumatoid factor (RF) negative and positive. The severity of joint damage is depicted as median Sharp-van der Heijde score ( SHS ) on the y axis and the follow-up years on the x axis for anti-carbamylated protein ( anti-CarP ) antibody immunoglobulin ( Ig )G1-positive and -negative patients in all RA patients analysed ( a ) and for ACPA- and RF-negative RA patients ( b ). β and p values are derived from the analysis model as described in the Methods and Results sections

    Article Snippet: Bound human IgG2 or IgG3 was detected using MAH-IgG2 (Nordic MUbio, Clone HP6014) or MAH-IgG3 (Nordic MUbio, Clone HP6080) continued with HRP-conjugated GAM-Ig (DAKO, P0447) and rabbit-anti-goat (RAG)-Ig (DAKO, P0449).

    Techniques: Derivative Assay

    Distribution of anti-CarP and ACPA isotypes and IgG subclasses. a Percentage positivity of anti-citrullinated protein antibody ( ACPA ; black bars ) or anti-carbamylated protein ( anti-CarP ) antibody ( grey bars ) immunoglobulin ( Ig )M, IgA, and IgG subclasses in ACPA and anti-CarP antibody IgG double-positive RA patients ( n = 114). b Percentage single- or double-positive for ACPA ( grey ) and anti-CarP antibody ( light grey ) isotypes and IgG subclasses in IgG double-positive RA patients. Circles are not to scale. Number of anti-CarP antibody and ACPA isotypes ( c ) and IgG subclasses ( d ) in anti-CarP antibody and ACPA IgG double-positive RA patients and at least positive for one IgG subclass ( n = 90)

    Journal: Arthritis Research & Therapy

    Article Title: The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

    doi: 10.1186/s13075-017-1392-z

    Figure Lengend Snippet: Distribution of anti-CarP and ACPA isotypes and IgG subclasses. a Percentage positivity of anti-citrullinated protein antibody ( ACPA ; black bars ) or anti-carbamylated protein ( anti-CarP ) antibody ( grey bars ) immunoglobulin ( Ig )M, IgA, and IgG subclasses in ACPA and anti-CarP antibody IgG double-positive RA patients ( n = 114). b Percentage single- or double-positive for ACPA ( grey ) and anti-CarP antibody ( light grey ) isotypes and IgG subclasses in IgG double-positive RA patients. Circles are not to scale. Number of anti-CarP antibody and ACPA isotypes ( c ) and IgG subclasses ( d ) in anti-CarP antibody and ACPA IgG double-positive RA patients and at least positive for one IgG subclass ( n = 90)

    Article Snippet: Bound human IgG2 or IgG3 was detected using MAH-IgG2 (Nordic MUbio, Clone HP6014) or MAH-IgG3 (Nordic MUbio, Clone HP6080) continued with HRP-conjugated GAM-Ig (DAKO, P0447) and rabbit-anti-goat (RAG)-Ig (DAKO, P0449).

    Techniques:

    Anti-CarP antibody isotypes and IgG subclasses are present in RA sera. ELISAs were performed to detect anti-carbamylated protein ( anti-CarP ) antibody isotypes ( a ) and immunoglobulin G ( IgG ) subclasses ( b ) in sera of 196 healthy controls ( HC ) and 373 rheumatoid arthritis ( RA ) patients. The mean ( red line ) plus two times the standard deviation in HC was established as the cut-off for the anti-CarP antibody isotypes. The 97 th percentile in HC was used as the cut-off for the IgG subclasses. The dotted line represents the cut-off. The specific anti-CarP reactivity is depicted in arbitrary units ( AU ) per millilitre. The number of samples tested and the percentage positivity is shown below the graphs. c Percentage positivity of anti-CarP antibody isotypes and IgG subclasses in all RA patients ( grey bars , n = 373), anti-citrullinated protein antibody ( ACPA ) IgG-positive RA patients ( dark grey bars , n = 217), ACPA IgG-negative RA patients ( black bars , n = 156), and HC ( light grey bars , n = 196)

    Journal: Arthritis Research & Therapy

    Article Title: The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

    doi: 10.1186/s13075-017-1392-z

    Figure Lengend Snippet: Anti-CarP antibody isotypes and IgG subclasses are present in RA sera. ELISAs were performed to detect anti-carbamylated protein ( anti-CarP ) antibody isotypes ( a ) and immunoglobulin G ( IgG ) subclasses ( b ) in sera of 196 healthy controls ( HC ) and 373 rheumatoid arthritis ( RA ) patients. The mean ( red line ) plus two times the standard deviation in HC was established as the cut-off for the anti-CarP antibody isotypes. The 97 th percentile in HC was used as the cut-off for the IgG subclasses. The dotted line represents the cut-off. The specific anti-CarP reactivity is depicted in arbitrary units ( AU ) per millilitre. The number of samples tested and the percentage positivity is shown below the graphs. c Percentage positivity of anti-CarP antibody isotypes and IgG subclasses in all RA patients ( grey bars , n = 373), anti-citrullinated protein antibody ( ACPA ) IgG-positive RA patients ( dark grey bars , n = 217), ACPA IgG-negative RA patients ( black bars , n = 156), and HC ( light grey bars , n = 196)

    Article Snippet: Bound human IgG2 or IgG3 was detected using MAH-IgG2 (Nordic MUbio, Clone HP6014) or MAH-IgG3 (Nordic MUbio, Clone HP6080) continued with HRP-conjugated GAM-Ig (DAKO, P0447) and rabbit-anti-goat (RAG)-Ig (DAKO, P0449).

    Techniques: Standard Deviation

    Effect of administration of rUre plus LT or placebo plus LT on conversion in specific antiurease serum and saliva IgG and IgA at 1 week after the fourth immunization. The H. pylori + or − designation reflects the status at endoscopy 10 months after the first immunization. ODU, OD units.

    Journal: Infection and Immunity

    Article Title: Immunization against Natural Helicobacter pylori Infection in Nonhuman Primates

    doi:

    Figure Lengend Snippet: Effect of administration of rUre plus LT or placebo plus LT on conversion in specific antiurease serum and saliva IgG and IgA at 1 week after the fourth immunization. The H. pylori + or − designation reflects the status at endoscopy 10 months after the first immunization. ODU, OD units.

    Article Snippet: The detecting antibodies were goat anti-rhesus IgG or IgA conjugated to horseradish peroxidase (Nordic Immunological Laboratories, The Netherlands).

    Techniques: