Journal: Korean Journal of Urology
Article Title: Structural modifications of the prostate in hypoxia, oxidative stress, and chronic ischemia
doi: 10.4111/kju.2015.56.3.187
Figure Lengend Snippet: Human prostate SMCs (A), ECs (B), and SCs (C) exhibited explicit reactions to hypoxia and oxidative stress. Lipid peroxidation was more prevalent in SMCs, whereas ECs appeared more susceptible to protein oxidation. Hypoxia caused lipid peroxidation in SMCs and protein oxidation in ECs. Oxidative stress led to protein oxidation and lipid peroxidation in SMCs, ECs, and SCs. Protein oxidation and lipid peroxidation suggest damage to protein- and lipid-containing structures of the cells, respectively. SMC, smooth muscle cell; EC, epithelial cell; SC, stromal cell; AOPP, advanced oxidation protein product; MDA, malondialdehyde. * Represent significance versus control.
Article Snippet: Primary human prostatic smooth muscle cells (SMCs), epithelial cells (ECs), and stromal cells (SCs) were obtained from Lonza (Allendale, NJ, USA).
Techniques: Control