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Herg K Channel Blocker, supplied by Millipore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Herg K Channel Blockers, supplied by Millipore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Millipore herg k channel blockers
Characterization of cardiomyocytes-derived from human pluripotent stem cells (hPSC-CMs). (A) Schematic diagram of hPSC differentiation into cardiomyocytes. (B) The morphology of differentiated hPSC-CMs derived from two hPSC cell lines (hESCs: H9 and hiPSCs: CMC-11; 10 × magnification). (C) The RT-qPCR was performed to measure the expression of cardiac sarcomeric markers, cTnT, and MYH6 genes, in hPSC-CMs. The data represent the mean (±SD) of at least two independent experiments performed in triplicate. Statistical analyses were determined using paired student's t -tests, and P < 0.05 was considered as significant (*). (D) Expression of TNNT2 and ACTN2 in hPSC-CMs (hESC-CMs [upper panel] and hiPSC-CMs [lower panel]) at day 15 of differentiation were determined by flow cytometry and immunofluorescence analyses. Scale bar, 100 μm. (E) Beating cardiomyocytes were prepared for action potential (AP) recording using the patch-clamp technique in hESC-CMs and field potential (FP) recording using a multielectrode array (MEA) system in hiPSC-CMs. The hPSC-CMs were treated with 100 <t>nM</t> <t>isoprenaline</t> (β 2 -adrenergic receptor agonist), 0.3 μM and 1 μM nifedipine (L-type Ca 2+ channel blocker), and 10 nM dofetilide and 30 nM E4031 (hERG K + channel blockers).
Herg K Channel Blockers, supplied by Millipore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/herg k channel blockers/product/Millipore
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
herg k channel blockers - by Bioz Stars, 2024-09
86/100 stars

Images

1) Product Images from "Antiviral activity and safety of remdesivir against SARS-CoV-2 infection in human pluripotent stem cell-derived cardiomyocytes"

Article Title: Antiviral activity and safety of remdesivir against SARS-CoV-2 infection in human pluripotent stem cell-derived cardiomyocytes

Journal: Antiviral Research

doi: 10.1016/j.antiviral.2020.104955

Characterization of cardiomyocytes-derived from human pluripotent stem cells (hPSC-CMs). (A) Schematic diagram of hPSC differentiation into cardiomyocytes. (B) The morphology of differentiated hPSC-CMs derived from two hPSC cell lines (hESCs: H9 and hiPSCs: CMC-11; 10 × magnification). (C) The RT-qPCR was performed to measure the expression of cardiac sarcomeric markers, cTnT, and MYH6 genes, in hPSC-CMs. The data represent the mean (±SD) of at least two independent experiments performed in triplicate. Statistical analyses were determined using paired student's t -tests, and P < 0.05 was considered as significant (*). (D) Expression of TNNT2 and ACTN2 in hPSC-CMs (hESC-CMs [upper panel] and hiPSC-CMs [lower panel]) at day 15 of differentiation were determined by flow cytometry and immunofluorescence analyses. Scale bar, 100 μm. (E) Beating cardiomyocytes were prepared for action potential (AP) recording using the patch-clamp technique in hESC-CMs and field potential (FP) recording using a multielectrode array (MEA) system in hiPSC-CMs. The hPSC-CMs were treated with 100 nM isoprenaline (β 2 -adrenergic receptor agonist), 0.3 μM and 1 μM nifedipine (L-type Ca 2+ channel blocker), and 10 nM dofetilide and 30 nM E4031 (hERG K + channel blockers).
Figure Legend Snippet: Characterization of cardiomyocytes-derived from human pluripotent stem cells (hPSC-CMs). (A) Schematic diagram of hPSC differentiation into cardiomyocytes. (B) The morphology of differentiated hPSC-CMs derived from two hPSC cell lines (hESCs: H9 and hiPSCs: CMC-11; 10 × magnification). (C) The RT-qPCR was performed to measure the expression of cardiac sarcomeric markers, cTnT, and MYH6 genes, in hPSC-CMs. The data represent the mean (±SD) of at least two independent experiments performed in triplicate. Statistical analyses were determined using paired student's t -tests, and P < 0.05 was considered as significant (*). (D) Expression of TNNT2 and ACTN2 in hPSC-CMs (hESC-CMs [upper panel] and hiPSC-CMs [lower panel]) at day 15 of differentiation were determined by flow cytometry and immunofluorescence analyses. Scale bar, 100 μm. (E) Beating cardiomyocytes were prepared for action potential (AP) recording using the patch-clamp technique in hESC-CMs and field potential (FP) recording using a multielectrode array (MEA) system in hiPSC-CMs. The hPSC-CMs were treated with 100 nM isoprenaline (β 2 -adrenergic receptor agonist), 0.3 μM and 1 μM nifedipine (L-type Ca 2+ channel blocker), and 10 nM dofetilide and 30 nM E4031 (hERG K + channel blockers).

Techniques Used: Derivative Assay, Quantitative RT-PCR, Expressing, Flow Cytometry, Immunofluorescence, Patch Clamp

herg k channel blockers  (Thermo Fisher)


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    Thermo Fisher herg k channel blockers
    Herg K Channel Blockers, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    herg k channel blockers  (Thermo Fisher)


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    Thermo Fisher herg k channel blockers
    Herg K Channel Blockers, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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