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Invitae Inc common hereditary cancers germline panel
Common Hereditary Cancers Germline Panel, supplied by Invitae Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hereditary+cancers/cancers+common+hereditary+panel/pmc13006393-172-0-6
Average 86 stars, based on 1 article reviews
common hereditary cancers germline panel - by Bioz Stars, 2026-09
86/100 stars

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Related Articles

Variant Assay:

Article Title: Multigenerational VHL family characterized by pathogenic germline ELOC variant: Response to belzutifan.
Article Snippet: Objective: We describe a large family of patients with canonical Von Hippel-Lindau (VHL) manifestations, including central nervous system and retinal hemangioblastomas, clear cell renal cell carcinoma (ccRCC), pancreatic neuroendocrine tumors, and pheochromocytomas, all who lacked any detectable alteration within the VHL gene.. Analysis of a ccRCC demonstrated a novel p.E92G variant in the Elongin C gene, ELOC, a known ccRCC tumor suppressor gene.. We aim to confirm that the ELOC variant is responsible for the VHL manifestations in this family.

Article Title:
Article Snippet: The results of the Invitae Common Hereditary Cancers Panel were compared to a validated high-throughput sequencing platform. .. In addition to evaluation of false positives, evaluation of false negatives (i.e., technical negative predictive value or TNPV) was performed by interrogating the wild-type flanking sequence spanning 100 to 800 bp for each variant of interest generated by the Invitae Common Hereditary Cancers Panel. .. Using this approach, over 72% of the entire reportable range was compared between the Invitae Common Hereditary Cancers Panel and the orthogonal method.

Mutagenesis:

Article Title: Neoadjuvant Fc-enhanced anti-CTLA-4 targets Tregs to augment androgen deprivation in high-risk prostate cancer: A randomized phase I trial
Article Snippet: .. Baseline germline mutation testing was performed at trial screening using the Invitae Common Hereditary Cancers Panel (48 genes) or the Invitae Multi-Cancer Panel (70 genes). ..

Article Title: Neoadjuvant Fc-enhanced anti-CTLA-4 targets Tregs to augment androgen deprivation in high-risk prostate cancer: A randomized phase I trial.
Article Snippet: .. Baseline germline mutation testing was performed at trial screening using the Invitae Common Hereditary Cancers Panel (48 genes) or the Invitae Multi-Cancer Panel (70 genes). ..

other:

Article Title: Neoadjuvant Fc-enhanced anti-CTLA-4 targets Tregs to augment androgen deprivation in high-risk prostate cancer: A randomized phase I trial
Article Snippet: Common Hereditary Cancers Germline Panel , Invitae , Cat# 01102.

Sequencing:

Article Title:
Article Snippet: The results of the Invitae Common Hereditary Cancers Panel were compared to a validated high-throughput sequencing platform. .. In addition to evaluation of false positives, evaluation of false negatives (i.e., technical negative predictive value or TNPV) was performed by interrogating the wild-type flanking sequence spanning 100 to 800 bp for each variant of interest generated by the Invitae Common Hereditary Cancers Panel. .. Using this approach, over 72% of the entire reportable range was compared between the Invitae Common Hereditary Cancers Panel and the orthogonal method.

Article Title: Unraveling Smooth Muscle-Rich Renal Cell Carcinoma: Clinical, Oncological, Genetic, and Pathological Insights.
Article Snippet: Objective: To present our institutional experience with Smooth Muscle-Rich Renal Cell Carcinoma (smrRCC), focusing on clinical presentation, surgical management, oncologic outcomes, and genetic features.. Material and methods: A retrospective chart review of patients with smrRCC treated at our institution between January 2008 and April 2025 was performed.. Clinical, surgical, pathological, and genetic data were collected and analyzed.

Generated:

Article Title:
Article Snippet: The results of the Invitae Common Hereditary Cancers Panel were compared to a validated high-throughput sequencing platform. .. In addition to evaluation of false positives, evaluation of false negatives (i.e., technical negative predictive value or TNPV) was performed by interrogating the wild-type flanking sequence spanning 100 to 800 bp for each variant of interest generated by the Invitae Common Hereditary Cancers Panel. .. Using this approach, over 72% of the entire reportable range was compared between the Invitae Common Hereditary Cancers Panel and the orthogonal method.



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