Journal: Marine Drugs

Article Title: Cytotoxic Furanoditerpenes from the Sponge Spongia tubulifera Collected in the Mexican Caribbean

doi: 10.3390/md17070416

Figure Lengend Snippet: Cytotoxic Activity Data (IC 50 in µM) of 1 , 4 , and 6 a .

Article Snippet: MTT ((3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide)) assays were performed on human lung carcinoma A549 ATCC® CCL-185TM, human skin melanoma A2058 ATCC® CRL-11147TM, hepatocyte carcinoma HepG2 ATCC® HB-8065TM, breast adenocarcinoma MCF7 ATCC® HTB-22TM, and pancreas carcinoma MiaPaca-2 ATCC® CRL-1420TM with doxorubicin as a positive control [ ].

Techniques: Activity Assay

Journal: Marine Drugs

Article Title: Amphidinol 22, a New Cytotoxic and Antifungal Amphidinol from the Dinoflagellate Amphidinium carterae

doi: 10.3390/md17070385

Figure Lengend Snippet: Percentage of growth inhibition of raw A. carterae extracts on cancer cells, bacteria and fungi.

Article Snippet: MTT assays were performed on human lung carcinoma A549 ATCC ® CCL-185™, human skin melanoma A2058 ATCC ® CRL-11147™, hepatocyte carcinoma HepG2 ATCC ® HB-8065™, breast adenocarcinoma MCF7 ATCC ® HTB-22™ and pancreas carcinoma MiaPaca-2 ATCC ® CRL-1420™ cell lines to assay the potential anticancer activity of amphidinol 22.

Techniques: Inhibition

Journal: Marine Drugs

Article Title: Amphidinol 22, a New Cytotoxic and Antifungal Amphidinol from the Dinoflagellate Amphidinium carterae

doi: 10.3390/md17070385

Figure Lengend Snippet: Percentage cell viability inhibition of A549 (lung), A2058 (skin), HepG2 (liver), MCF7 (breast) and Miapaca-2 (pancreas) cancer cell lines after incubation for 72 h with 0.098, 0.195, 0.391, 0.781, 1.563, 3.125, 6.250, 12.5, 25, 50 µM of amphidinol 22 (** for p < 0.01 and *** for p < 0.001, Student’s t -test). Experiments were performed in triplicate.

Article Snippet: MTT assays were performed on human lung carcinoma A549 ATCC ® CCL-185™, human skin melanoma A2058 ATCC ® CRL-11147™, hepatocyte carcinoma HepG2 ATCC ® HB-8065™, breast adenocarcinoma MCF7 ATCC ® HTB-22™ and pancreas carcinoma MiaPaca-2 ATCC ® CRL-1420™ cell lines to assay the potential anticancer activity of amphidinol 22.

Techniques: Inhibition, Incubation