Structured Review

STERIS h2 o2
H2 O2, supplied by STERIS, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/h2 o2/product/STERIS
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
h2 o2 - by Bioz Stars, 2021-03
86/100 stars

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Activity Assay:

Article Title: Mechanism of Sporicidal Activity for the Synergistic Combination of Peracetic Acid and Hydrogen Peroxide
Article Snippet: Thus, the susceptibilities of the three strains to P/H match those to PAA more closely than those to H2 O2 , implying that the mechanism of activity is more similar to that of PAA than to that of H2 O2 . .. Given the similar susceptibility profiles of the three strains for PAA and P/H and the fact that H2 O2 potentiated the activity of PAA more than PAA did that of H2 O2 , a possible explanation for the enhanced activity of the P/H combination is the generation of PAA from excess H2 O2 and residual acetate, as suggested previously ( ). ..

Article Title: Mechanism of Sporicidal Activity for the Synergistic Combination of Peracetic Acid and Hydrogen Peroxide
Article Snippet: .. Assuming that the synergistic activity of PAA and H2 O2 is dependent upon a weakening of the spore coat defensive barrier, we may also expect hypochlorite to show a similar synergistic activity in combination with H2 O2 , since, like PAA, hypochlorite is most active against spores which lack a complete spore coat ( ). .. Indeed, Marquis et al. ( ) showed some synergy between hypochlorite and H2 O2 ; however, they did not state the pH of the solutions tested, and because hypochlorite is considerably more active at lower pHs, one must consider that the effect of H2 O2 lowering the pH of the system may have been responsible for the enhanced activity of these two biocides in combination.

Article Title: Mechanism of Sporicidal Activity for the Synergistic Combination of Peracetic Acid and Hydrogen Peroxide
Article Snippet: The addition of lower ( < 0.04% [wt/vol]) concentrations of PAA had a relatively minor effect on the sporicidal activity of H2 O2 , as the concentration exponent (η) of H2 O2 hardly changed relative to that for systems containing H2 O2 alone ( ). .. Conversely, the addition of even the lowest concentration of H2 O2 tested (0.1% [wt/vol]) to PAA considerably reduced the η value for PAA , indicating that H2 O2 had a far more profound effect on the activity of PAA than PAA did on the activity of H2 O2 . .. Addressing the possibility of a shifting equilibrium of PAA and H2 O2 .

other:

Article Title: Mechanism of Sporicidal Activity for the Synergistic Combination of Peracetic Acid and Hydrogen Peroxide
Article Snippet: To assay for H2 O2 , the aliquots were combined with potassium iodide (10%) in the presence of sodium molybdate (3%), forming triiodide through oxidation by H2 O2 .

Article Title: Mechanism of Sporicidal Activity for the Synergistic Combination of Peracetic Acid and Hydrogen Peroxide
Article Snippet: It has been suggested that a likely reason for “synergy” between these two microbicides is the generation of PAA from H2 O2 and residual acetic acid, which is invariably present in PAA solutions in order to improve its stability ( ).

Article Title: Mechanism of Sporicidal Activity for the Synergistic Combination of Peracetic Acid and Hydrogen Peroxide
Article Snippet: We therefore speculate that H2 O2 rapidly interacts with reactive sites within the spore coat without necessarily removing significant amounts of protein, thus allowing PAA to pass through to react with other targets within the spore.

Concentration Assay:

Article Title: Mechanism of Sporicidal Activity for the Synergistic Combination of Peracetic Acid and Hydrogen Peroxide
Article Snippet: It is therefore possible that in combination with PAA, H2 O2 acts to strip proteins from the spore coat, effectively removing one of the principal barriers to PAA killing ( ) and decreasing the time required for PAA to exert a sporicidal effect. .. However, we showed that spores became sensitized to PAA after only very brief exposures to a low concentration of H2 O2 . ..

Article Title: Mechanism of Sporicidal Activity for the Synergistic Combination of Peracetic Acid and Hydrogen Peroxide
Article Snippet: The addition of lower ( < 0.04% [wt/vol]) concentrations of PAA had a relatively minor effect on the sporicidal activity of H2 O2 , as the concentration exponent (η) of H2 O2 hardly changed relative to that for systems containing H2 O2 alone ( ). .. Conversely, the addition of even the lowest concentration of H2 O2 tested (0.1% [wt/vol]) to PAA considerably reduced the η value for PAA , indicating that H2 O2 had a far more profound effect on the activity of PAA than PAA did on the activity of H2 O2 . .. Addressing the possibility of a shifting equilibrium of PAA and H2 O2 .

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    STERIS h2 o2
    H2 O2, supplied by STERIS, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/h2 o2/product/STERIS
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    h2 o2 - by Bioz Stars, 2021-03
    86/100 stars
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