Structured Review

Fisher Bioreagents h2 o2
H2 O2, supplied by Fisher Bioreagents, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/h2 o2/product/Fisher Bioreagents
Average 86 stars, based on 1 article reviews
Price from $9.99 to $1999.99
h2 o2 - by Bioz Stars, 2021-03
86/100 stars

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Inhibition:

Article Title: Calcium influx-dependent differential actions of superoxide and hydrogen peroxide on microvessel permeability
Article Snippet: Heterogeneous Ca2+ responses at individual endothelial cell levels were illustrated by Ca2+ imaging in both H2 O2 and HX/XO perfused vessels, a pattern consistent with observations in inflammatory mediator-stimulated microvessels ( , ). .. The results that inhibition of Ca2+ influx by LaCl3 prevented HX/XO and H2 O2 -induced L p increases indicate a critical role of Ca2+ influx in both superoxide and H2 O2-induced permeability increases. ..

Permeability:

Article Title: Calcium influx-dependent differential actions of superoxide and hydrogen peroxide on microvessel permeability
Article Snippet: Heterogeneous Ca2+ responses at individual endothelial cell levels were illustrated by Ca2+ imaging in both H2 O2 and HX/XO perfused vessels, a pattern consistent with observations in inflammatory mediator-stimulated microvessels ( , ). .. The results that inhibition of Ca2+ influx by LaCl3 prevented HX/XO and H2 O2 -induced L p increases indicate a critical role of Ca2+ influx in both superoxide and H2 O2-induced permeability increases. ..

Article Title: Calcium influx-dependent differential actions of superoxide and hydrogen peroxide on microvessel permeability
Article Snippet: In addition, H2 O2 is a recognized potent dilator of resistance vessels and may play an important role in the regulation of blood flow under certain pathological conditions ( , ). .. Our results indicated that the long-term effect of H2 O2 on endothelial cells and microvessel permeability, even at subcytotoxic concentrations, should not be overlooked. .. The physiological concentrations of H2 O2 responsible for normal intracellular cell signaling were reported less than 1 μM, usually 7- to 10-fold below the extracellular concentration, whereas local pathological concentrations of H2 O2 can be significantly higher ( ).

Article Title: Calcium influx-dependent differential actions of superoxide and hydrogen peroxide on microvessel permeability
Article Snippet: SOD completely abolished the enzymatic reaction of CL, as well as HX/XO-induced increases in endothelial [Ca2+ ]i and microvessel L p , which indicated that in the absence of superoxide, the amount of H2 O2 produced by HX/XO reaction plus that catalyzed by SOD from HX/XO-generated superoxide does not have the same effect on L p and [Ca2+ ]i when superoxide was present. .. Additionally, the direct perfusion of H2 O2 at 100 or 500 μM showing no immediate increase in either permeability or endothelial [Ca2+ ]i supports that superoxide generated by HX/XO or released by fMLP-stimulated neutrophils, and not the H2 O2 produced by HX/XO reaction or spontaneously catalyzed from superoxide, is responsible for the immediate and transient increases in microvessel permeability. ..

Article Title: Calcium influx-dependent differential actions of superoxide and hydrogen peroxide on microvessel permeability
Article Snippet: Theses results indicated that the H2 O2 -induced increases in microvessel permeability depend on Ca2+ influx via LaCl3-sensitive pathways. .. Our study provided the first evidence that superoxide and H2 O2 have differential actions on endothelial [Ca2+ ]i and microvessel permeability and that increased Ca2+ influx contributes to both ROS-induced permeability increases in intact microvessels. .. The distinct time courses of superoxide and H2 O2 -induced increases in endothelial [Ca2+ ]i and permeability indicate that these two ROS may trigger signaling pathways or evoke cellular damage via different cellular mechanisms.

Article Title: Calcium influx-dependent differential actions of superoxide and hydrogen peroxide on microvessel permeability
Article Snippet: Our measurements of H2 O2 -induced increases in endothelial [Ca2+ ]i demonstrated a time course correlated to that of the L p changes. .. In contrast with superoxide-induced transient increases in endothelial [Ca2+ ]i and microvessel permeability, the H2 O2 -induced increases in [Ca2+ ]i and microvessel permeability can only be partially reversed after the perfusion of H2 O2 at 100 μM for 1 h and are not reversible after 1 h of H2 O2 perfusion at 500 μM. .. This indicates that long-term exposure to H2 O2 caused irreversible damage in the vascular wall.

Generated:

Article Title: Calcium influx-dependent differential actions of superoxide and hydrogen peroxide on microvessel permeability
Article Snippet: SOD completely abolished the enzymatic reaction of CL, as well as HX/XO-induced increases in endothelial [Ca2+ ]i and microvessel L p , which indicated that in the absence of superoxide, the amount of H2 O2 produced by HX/XO reaction plus that catalyzed by SOD from HX/XO-generated superoxide does not have the same effect on L p and [Ca2+ ]i when superoxide was present. .. Additionally, the direct perfusion of H2 O2 at 100 or 500 μM showing no immediate increase in either permeability or endothelial [Ca2+ ]i supports that superoxide generated by HX/XO or released by fMLP-stimulated neutrophils, and not the H2 O2 produced by HX/XO reaction or spontaneously catalyzed from superoxide, is responsible for the immediate and transient increases in microvessel permeability. ..

Produced:

Article Title: Calcium influx-dependent differential actions of superoxide and hydrogen peroxide on microvessel permeability
Article Snippet: SOD completely abolished the enzymatic reaction of CL, as well as HX/XO-induced increases in endothelial [Ca2+ ]i and microvessel L p , which indicated that in the absence of superoxide, the amount of H2 O2 produced by HX/XO reaction plus that catalyzed by SOD from HX/XO-generated superoxide does not have the same effect on L p and [Ca2+ ]i when superoxide was present. .. Additionally, the direct perfusion of H2 O2 at 100 or 500 μM showing no immediate increase in either permeability or endothelial [Ca2+ ]i supports that superoxide generated by HX/XO or released by fMLP-stimulated neutrophils, and not the H2 O2 produced by HX/XO reaction or spontaneously catalyzed from superoxide, is responsible for the immediate and transient increases in microvessel permeability. ..

other:

Article Title: Calcium influx-dependent differential actions of superoxide and hydrogen peroxide on microvessel permeability
Article Snippet: Each vessel was then perfused with either 100 μM ( n = 5) or 500 μM ( n = 4) of H2 O2 for 60 min in the presence of LaCl3 .

Article Title: Calcium influx-dependent differential actions of superoxide and hydrogen peroxide on microvessel permeability
Article Snippet: The effect of LaCl3 (50 μM) on H2 O2 -induced increases in endothelial [Ca2+ ]i was examined in nine microvessels.

Article Title: Calcium influx-dependent differential actions of superoxide and hydrogen peroxide on microvessel permeability
Article Snippet: After baseline measurements, six of the vessels were perfused with 100 μM H2 O2 and the other six vessels were perfused with 500 μM of H2 O2 .

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    Fisher Bioreagents h2 o2 solution
    H2 O2 Solution, supplied by Fisher Bioreagents, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/h2 o2 solution/product/Fisher Bioreagents
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    h2 o2 solution - by Bioz Stars, 2021-03
    86/100 stars
      Buy from Supplier

    86
    Fisher Bioreagents h2 o2
    H2 O2, supplied by Fisher Bioreagents, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/h2 o2/product/Fisher Bioreagents
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    h2 o2 - by Bioz Stars, 2021-03
    86/100 stars
      Buy from Supplier

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