genechip system  (Thermo Fisher)


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    Structured Review

    Thermo Fisher genechip system
    Venn diagram of genes that were differentially expressed in BCC of the eyelid (patients 1 and 2). Gene expression analysis was performed using a <t>GeneChip</t> ® microarray system and the GeneSpring software. The numbers of upregulated genes are shown. In the samples from patients 1 and 2, we found that 687 and 713 genes, respectively, showed ≥5.0-fold higher expression that that noted in NHEKs. NHEK, normal human epidermal keratinocytes; BCC, basal cell carcinoma.
    Genechip System, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 97/100, based on 40 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/genechip system/product/Thermo Fisher
    Average 97 stars, based on 40 article reviews
    Price from $9.99 to $1999.99
    genechip system - by Bioz Stars, 2022-11
    97/100 stars

    Images

    1) Product Images from "Gene networks in basal cell carcinoma of the eyelid, analyzed using gene expression profiling"

    Article Title: Gene networks in basal cell carcinoma of the eyelid, analyzed using gene expression profiling

    Journal: Oncology Letters

    doi: 10.3892/ol.2018.9484

    Venn diagram of genes that were differentially expressed in BCC of the eyelid (patients 1 and 2). Gene expression analysis was performed using a GeneChip ® microarray system and the GeneSpring software. The numbers of upregulated genes are shown. In the samples from patients 1 and 2, we found that 687 and 713 genes, respectively, showed ≥5.0-fold higher expression that that noted in NHEKs. NHEK, normal human epidermal keratinocytes; BCC, basal cell carcinoma.
    Figure Legend Snippet: Venn diagram of genes that were differentially expressed in BCC of the eyelid (patients 1 and 2). Gene expression analysis was performed using a GeneChip ® microarray system and the GeneSpring software. The numbers of upregulated genes are shown. In the samples from patients 1 and 2, we found that 687 and 713 genes, respectively, showed ≥5.0-fold higher expression that that noted in NHEKs. NHEK, normal human epidermal keratinocytes; BCC, basal cell carcinoma.

    Techniques Used: Expressing, Microarray, Software

    2) Product Images from "Comparison of biological effects of modulated electro-hyperthermia and conventional heat treatment in human lymphoma U937 cells"

    Article Title: Comparison of biological effects of modulated electro-hyperthermia and conventional heat treatment in human lymphoma U937 cells

    Journal: Cell Death Discovery

    doi: 10.1038/cddiscovery.2016.39

    The GeneChip heat map. The analysis revealed a whole cluster of genes, which are highly up-regulated in the case of mEHT-treated samples, but not in WHT ( a ). The ingenuity pathway analysis clearly demonstrated a specific gene network containing cell death-related genes, such as EGR1, JUN, and CDKN1A. The expression levels of these genes were elevated only in the cells treated with mEHT ( b ). A specific cytoprotective gene network (heat shock proteins, HSPs) was activated in the case of WHT treatment, but not in mEHT-treated samples ( c ). The ingenuity pathway analysis predicted ERK activation and the relationship between JUN and ERK in OTM-treated cells. This activation mechanism is missing in the case of WHT-treated cells ( d ).
    Figure Legend Snippet: The GeneChip heat map. The analysis revealed a whole cluster of genes, which are highly up-regulated in the case of mEHT-treated samples, but not in WHT ( a ). The ingenuity pathway analysis clearly demonstrated a specific gene network containing cell death-related genes, such as EGR1, JUN, and CDKN1A. The expression levels of these genes were elevated only in the cells treated with mEHT ( b ). A specific cytoprotective gene network (heat shock proteins, HSPs) was activated in the case of WHT treatment, but not in mEHT-treated samples ( c ). The ingenuity pathway analysis predicted ERK activation and the relationship between JUN and ERK in OTM-treated cells. This activation mechanism is missing in the case of WHT-treated cells ( d ).

    Techniques Used: Expressing, Activation Assay

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