Journal: EJNMMI Radiopharmacy and Chemistry
Article Title: Validation of a radiosynthesis method and a novel quality control system for [ 68 Ga]Ga-MAA: is TLC enough to assess radiopharmaceutical quality?
doi: 10.1186/s41181-024-00302-x
Figure Lengend Snippet: Synthesis production scheme of [ 68 Ga]Ga-MAA: 1. 68Ge/68 Ga generator elution and [ 68 Ga]GaCl 3 eluate purification. 2. Mixing the [ 68 Ga]GaCl 3 eluate with the MAA. 3. Heat the reaction solution at (25°–40°–75°–95 °C). 3. Filtration of [ 68 Ga]Ga-MAA. 4. Collection of [ 68 Ga]Ga-MAA for the final formulation
Article Snippet: The elution of a pharmaceutical grade, GMP certified and compliant with European Pharmacopoeia 68Ge/68 Ga generator (GalliaPharma®, Eckert and Ziegler) was carried out using the GRP module 3 V automated synthesis system (Scintomics GmbH, Fürstenfeldbruck, Germany) from Scintomics GmbH.
Techniques: Purification, Filtration, Formulation