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dio1 b 7 mab  (Santa Cruz Biotechnology)


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    Santa Cruz Biotechnology dio1 b 7 mab
    Expression of markers of T 3 action in the liver of ChEL-KI mice. ( A ) Expression of malic enzyme 1 (ME1). Lower panel: SDS-polyacrylamide gel electrophoresis of liver homogenates from 3-month-old ChEL-KI mice, cog / cog animals, and wild-type (WT) mice, followed by immunoblotting with anti-ME1 antibodies and anti-β-actin antibodies as indicated. Upper panel: Graph shows the densitometric quantitation of hepatic ME1 protein expression normalized to β-actin. ( B ) Expression of type-1 deiodinase <t>(D1).</t> Lower panel: SDS-polyacrylamide gel electrophoresis of liver homogenates from ChEL-KI mice, cog / cog animals, and WT controls, followed by immunoblotting with anti-D1 antibodies and anti-β-actin antibodies as indicated. Upper panel: Graph shows the densitometric quantitation of hepatic D1 protein expression normalized to β-actin. Each dot represents an individual animal, with circles representing females and squares representing males; n = 8–11 animals per group; mean ± SD; ns, not significant ( p > 0.05), p ; **** p < 0.0001 (one-way ANOVA with Tukey’s post hoc test).
    Dio1 B 7 Mab, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dio1 b 7 mab/product/Santa Cruz Biotechnology
    Average 92 stars, based on 10 article reviews
    dio1 b 7 mab - by Bioz Stars, 2026-06
    92/100 stars

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    1) Product Images from "A Genetically-Engineered Thyroid Gland Built for Selective Triiodothyronine Secretion"

    Article Title: A Genetically-Engineered Thyroid Gland Built for Selective Triiodothyronine Secretion

    Journal: International Journal of Molecular Sciences

    doi: 10.3390/ijms26157166

    Expression of markers of T 3 action in the liver of ChEL-KI mice. ( A ) Expression of malic enzyme 1 (ME1). Lower panel: SDS-polyacrylamide gel electrophoresis of liver homogenates from 3-month-old ChEL-KI mice, cog / cog animals, and wild-type (WT) mice, followed by immunoblotting with anti-ME1 antibodies and anti-β-actin antibodies as indicated. Upper panel: Graph shows the densitometric quantitation of hepatic ME1 protein expression normalized to β-actin. ( B ) Expression of type-1 deiodinase (D1). Lower panel: SDS-polyacrylamide gel electrophoresis of liver homogenates from ChEL-KI mice, cog / cog animals, and WT controls, followed by immunoblotting with anti-D1 antibodies and anti-β-actin antibodies as indicated. Upper panel: Graph shows the densitometric quantitation of hepatic D1 protein expression normalized to β-actin. Each dot represents an individual animal, with circles representing females and squares representing males; n = 8–11 animals per group; mean ± SD; ns, not significant ( p > 0.05), p ; **** p < 0.0001 (one-way ANOVA with Tukey’s post hoc test).
    Figure Legend Snippet: Expression of markers of T 3 action in the liver of ChEL-KI mice. ( A ) Expression of malic enzyme 1 (ME1). Lower panel: SDS-polyacrylamide gel electrophoresis of liver homogenates from 3-month-old ChEL-KI mice, cog / cog animals, and wild-type (WT) mice, followed by immunoblotting with anti-ME1 antibodies and anti-β-actin antibodies as indicated. Upper panel: Graph shows the densitometric quantitation of hepatic ME1 protein expression normalized to β-actin. ( B ) Expression of type-1 deiodinase (D1). Lower panel: SDS-polyacrylamide gel electrophoresis of liver homogenates from ChEL-KI mice, cog / cog animals, and WT controls, followed by immunoblotting with anti-D1 antibodies and anti-β-actin antibodies as indicated. Upper panel: Graph shows the densitometric quantitation of hepatic D1 protein expression normalized to β-actin. Each dot represents an individual animal, with circles representing females and squares representing males; n = 8–11 animals per group; mean ± SD; ns, not significant ( p > 0.05), p ; **** p < 0.0001 (one-way ANOVA with Tukey’s post hoc test).

    Techniques Used: Expressing, Polyacrylamide Gel Electrophoresis, Western Blot, Quantitation Assay



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    Santa Cruz Biotechnology dio1 b 7 mab
    Expression of markers of T 3 action in the liver of ChEL-KI mice. ( A ) Expression of malic enzyme 1 (ME1). Lower panel: SDS-polyacrylamide gel electrophoresis of liver homogenates from 3-month-old ChEL-KI mice, cog / cog animals, and wild-type (WT) mice, followed by immunoblotting with anti-ME1 antibodies and anti-β-actin antibodies as indicated. Upper panel: Graph shows the densitometric quantitation of hepatic ME1 protein expression normalized to β-actin. ( B ) Expression of type-1 deiodinase <t>(D1).</t> Lower panel: SDS-polyacrylamide gel electrophoresis of liver homogenates from ChEL-KI mice, cog / cog animals, and WT controls, followed by immunoblotting with anti-D1 antibodies and anti-β-actin antibodies as indicated. Upper panel: Graph shows the densitometric quantitation of hepatic D1 protein expression normalized to β-actin. Each dot represents an individual animal, with circles representing females and squares representing males; n = 8–11 animals per group; mean ± SD; ns, not significant ( p > 0.05), p ; **** p < 0.0001 (one-way ANOVA with Tukey’s post hoc test).
    Dio1 B 7 Mab, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dio1 b 7 mab/product/Santa Cruz Biotechnology
    Average 92 stars, based on 1 article reviews
    dio1 b 7 mab - by Bioz Stars, 2026-06
    92/100 stars
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    Expression of markers of T 3 action in the liver of ChEL-KI mice. ( A ) Expression of malic enzyme 1 (ME1). Lower panel: SDS-polyacrylamide gel electrophoresis of liver homogenates from 3-month-old ChEL-KI mice, cog / cog animals, and wild-type (WT) mice, followed by immunoblotting with anti-ME1 antibodies and anti-β-actin antibodies as indicated. Upper panel: Graph shows the densitometric quantitation of hepatic ME1 protein expression normalized to β-actin. ( B ) Expression of type-1 deiodinase (D1). Lower panel: SDS-polyacrylamide gel electrophoresis of liver homogenates from ChEL-KI mice, cog / cog animals, and WT controls, followed by immunoblotting with anti-D1 antibodies and anti-β-actin antibodies as indicated. Upper panel: Graph shows the densitometric quantitation of hepatic D1 protein expression normalized to β-actin. Each dot represents an individual animal, with circles representing females and squares representing males; n = 8–11 animals per group; mean ± SD; ns, not significant ( p > 0.05), p ; **** p < 0.0001 (one-way ANOVA with Tukey’s post hoc test).

    Journal: International Journal of Molecular Sciences

    Article Title: A Genetically-Engineered Thyroid Gland Built for Selective Triiodothyronine Secretion

    doi: 10.3390/ijms26157166

    Figure Lengend Snippet: Expression of markers of T 3 action in the liver of ChEL-KI mice. ( A ) Expression of malic enzyme 1 (ME1). Lower panel: SDS-polyacrylamide gel electrophoresis of liver homogenates from 3-month-old ChEL-KI mice, cog / cog animals, and wild-type (WT) mice, followed by immunoblotting with anti-ME1 antibodies and anti-β-actin antibodies as indicated. Upper panel: Graph shows the densitometric quantitation of hepatic ME1 protein expression normalized to β-actin. ( B ) Expression of type-1 deiodinase (D1). Lower panel: SDS-polyacrylamide gel electrophoresis of liver homogenates from ChEL-KI mice, cog / cog animals, and WT controls, followed by immunoblotting with anti-D1 antibodies and anti-β-actin antibodies as indicated. Upper panel: Graph shows the densitometric quantitation of hepatic D1 protein expression normalized to β-actin. Each dot represents an individual animal, with circles representing females and squares representing males; n = 8–11 animals per group; mean ± SD; ns, not significant ( p > 0.05), p ; **** p < 0.0001 (one-way ANOVA with Tukey’s post hoc test).

    Article Snippet: DYKDDDDK Tag rabbit mAb (D6W5B, Cell Signaling Technology, Danvers, MA, USA), rabbit monoclonal [EPR9730] to thyroglobulin Ab (Abcam, Cambridge, UK), T 3 mouse mAb (3A6, Invitrogen, Waltham, MA, USA), DIO1 (B-7) mAb (sc-515198, Santa Cruz Biotechnologies, Dallas, TX, USA), ME1 (C-6) mAb (sc-365891, Santa Cruz Biotechnologies, Dallas, TX, USA), Ki67 mAb (ab16667, Abcam, Cambridge, UK), KDEL (10C) mAb (ADI-SPA-827-D Enzo Life Sciences, Long Island, NY, USA), anti-Flag M2 mAb (F1804, MilliporeSigma, Burlington, MA, USA), β-Actin (C4) mAb (sc-47778, Santa Cruz Biotechnologies, Dallas, TX, USA), and HSP 90α/β (F-8) mAb (sc-13119, Santa Cruz Biotechnologies, Dallas, TX, USA) were used.

    Techniques: Expressing, Polyacrylamide Gel Electrophoresis, Western Blot, Quantitation Assay