nicotinic acetylcholine receptor agonist dimethylphenylpiperazinium  (Millipore)

 
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    Millipore nicotinic acetylcholine receptor agonist dimethylphenylpiperazinium
    Neither 20 μM mecamylamine nor 20 μM hexamethonium had an effect on responses to 3 mM S(−)-nicotine in rat OSNs (A,B) and human cultured olfactory cells (C,D). Mecamylamine also had no effect on nicotine responses in fresh human biopsy OSNs (E). <t>DMPP</t> (10 μM) did not stimulate nicotine-sensitive rat OSNs (F).
    Nicotinic Acetylcholine Receptor Agonist Dimethylphenylpiperazinium, supplied by Millipore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nicotinic acetylcholine receptor agonist dimethylphenylpiperazinium/product/Millipore
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    nicotinic acetylcholine receptor agonist dimethylphenylpiperazinium - by Bioz Stars, 2023-02
    86/100 stars

    Images

    1) Product Images from "Cellular Basis for the Olfactory Response to Nicotine"

    Article Title: Cellular Basis for the Olfactory Response to Nicotine

    Journal: ACS Chemical Neuroscience

    doi: 10.1021/cn900042c

    Neither 20 μM mecamylamine nor 20 μM hexamethonium had an effect on responses to 3 mM S(−)-nicotine in rat OSNs (A,B) and human cultured olfactory cells (C,D). Mecamylamine also had no effect on nicotine responses in fresh human biopsy OSNs (E). DMPP (10 μM) did not stimulate nicotine-sensitive rat OSNs (F).
    Figure Legend Snippet: Neither 20 μM mecamylamine nor 20 μM hexamethonium had an effect on responses to 3 mM S(−)-nicotine in rat OSNs (A,B) and human cultured olfactory cells (C,D). Mecamylamine also had no effect on nicotine responses in fresh human biopsy OSNs (E). DMPP (10 μM) did not stimulate nicotine-sensitive rat OSNs (F).

    Techniques Used: Cell Culture

    nicotinic acetylcholine receptor agonist dimethylphenylpiperazinium  (Millipore)

     
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    Structured Review

    Millipore nicotinic acetylcholine receptor agonist dimethylphenylpiperazinium
    Neither 20 μM mecamylamine nor 20 μM hexamethonium had an effect on responses to 3 mM S(−)-nicotine in rat OSNs (A,B) and human cultured olfactory cells (C,D). Mecamylamine also had no effect on nicotine responses in fresh human biopsy OSNs (E). <t>DMPP</t> (10 μM) did not stimulate nicotine-sensitive rat OSNs (F).
    Nicotinic Acetylcholine Receptor Agonist Dimethylphenylpiperazinium, supplied by Millipore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nicotinic acetylcholine receptor agonist dimethylphenylpiperazinium/product/Millipore
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    nicotinic acetylcholine receptor agonist dimethylphenylpiperazinium - by Bioz Stars, 2023-02
    86/100 stars

    Images

    1) Product Images from "Cellular Basis for the Olfactory Response to Nicotine"

    Article Title: Cellular Basis for the Olfactory Response to Nicotine

    Journal: ACS Chemical Neuroscience

    doi: 10.1021/cn900042c

    Neither 20 μM mecamylamine nor 20 μM hexamethonium had an effect on responses to 3 mM S(−)-nicotine in rat OSNs (A,B) and human cultured olfactory cells (C,D). Mecamylamine also had no effect on nicotine responses in fresh human biopsy OSNs (E). DMPP (10 μM) did not stimulate nicotine-sensitive rat OSNs (F).
    Figure Legend Snippet: Neither 20 μM mecamylamine nor 20 μM hexamethonium had an effect on responses to 3 mM S(−)-nicotine in rat OSNs (A,B) and human cultured olfactory cells (C,D). Mecamylamine also had no effect on nicotine responses in fresh human biopsy OSNs (E). DMPP (10 μM) did not stimulate nicotine-sensitive rat OSNs (F).

    Techniques Used: Cell Culture

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    Millipore nicotinic acetylcholine receptor agonist dimethylphenylpiperazinium
    Neither 20 μM mecamylamine nor 20 μM hexamethonium had an effect on responses to 3 mM S(−)-nicotine in rat OSNs (A,B) and human cultured olfactory cells (C,D). Mecamylamine also had no effect on nicotine responses in fresh human biopsy OSNs (E). <t>DMPP</t> (10 μM) did not stimulate nicotine-sensitive rat OSNs (F).
    Nicotinic Acetylcholine Receptor Agonist Dimethylphenylpiperazinium, supplied by Millipore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nicotinic acetylcholine receptor agonist dimethylphenylpiperazinium/product/Millipore
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    nicotinic acetylcholine receptor agonist dimethylphenylpiperazinium - by Bioz Stars, 2023-02
    86/100 stars
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    Neither 20 μM mecamylamine nor 20 μM hexamethonium had an effect on responses to 3 mM S(−)-nicotine in rat OSNs (A,B) and human cultured olfactory cells (C,D). Mecamylamine also had no effect on nicotine responses in fresh human biopsy OSNs (E). DMPP (10 μM) did not stimulate nicotine-sensitive rat OSNs (F).

    Journal: ACS Chemical Neuroscience

    Article Title: Cellular Basis for the Olfactory Response to Nicotine

    doi: 10.1021/cn900042c

    Figure Lengend Snippet: Neither 20 μM mecamylamine nor 20 μM hexamethonium had an effect on responses to 3 mM S(−)-nicotine in rat OSNs (A,B) and human cultured olfactory cells (C,D). Mecamylamine also had no effect on nicotine responses in fresh human biopsy OSNs (E). DMPP (10 μM) did not stimulate nicotine-sensitive rat OSNs (F).

    Article Snippet: Other compounds used in this study were as follows: S (−)-nicotine (Philip Morris, Richmond, VA, >99% by GC), R (+)-nicotine (Toronto Research Chemical Inc., North York, Canada, 97% by TLC, NMR and optical rotation), noncompetitive nicotinic acetylcholine receptor antagonist mecamylamine hydrochloride (20 μM), competitive nicotinic acetylcholine receptor antagonist hexamethonium chloride (20 μM), nicotinic acetylcholine receptor agonist dimethylphenylpiperazinium (DMPP, 10 μM), adenylate cyclase inhibitor MDL-12,330A hydrochloride (20 μM), phospholipase C antagonists U-73122 (20 μM) and neomycin (1 mM), sarcoplasmic reticulum Ca 2+ -ATPase inhibitor thapsigargin (200 nM, Calbiochem, San Diego, CA), adenylate cyclase activator forskolin, phosphodiesterase inhibitor isobutylmethylxanthine (IBMX), leupeptin, l -cysteine, papain, and DNase I (Roche Diagnostics, Indianapolis, IN).

    Techniques: Cell Culture